Following yesterday's @ESEndocrinology postgraduate course on gestational endocrinology:
I wanted to share one of the questions and a quick update on a the strategy to limit antithyroid drug exposure in pregnancy (that is still fairly unknown). What would you have answered??

I am quarantined in London, so #Tweetorial time💂‍♂️⏰

Should we treat subclinical hypothyroidism during pregnancy?

A tweetorial on physiology, overdiagnosis, risk stratification and treatment harms.

Do you treat subclinical hypothyroidism during pregnancy?❌✅ Subclinical hypothyroidism [⬆️TSH, ↔️FT4] occurs in ~3.5% of pregnancies.

- Short differential (fig)
- No/Mild symptomatology overlaps with pregnancy, doesn't distinguish
- Consistent associations of modestly increased risk of miscarriage, preterm birth and low birth weight.

A tweetorial on hyperthyroidism during pregnancy.

Following yesterday's @ObsMedEd webinar on thyroid disease in pregnancy:

#MedTwitter #FirstTweetorial
Feedback and discussion more than welcome!

[Picture: neonatal Graves' disease] nejm.org/doi/full/10.10… Hyperthyroidism occurs in 1%-2.2% of pregnancies, depending on the reference range you use.

Probably 95% of hyperthyroidism in pregnancy is physiological due to thyroid stimulation by hCG.

liebertpub.com/doi/abs/10.108…
academic.oup.com/clinchem/artic…
Figure from rdcu.be/uKOO