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Craig Wilen Profile picture
Craig Wilen
@WilenLab
Physician-scientist. Dad. Husband. Associate Professor @yaleibio @yale_labmed. We study host-viral interactions and immune evasion esp of #covid #norovirus
Jan 14, 2021 • 9 tweets • 5 min read
Excited to share our new paper led by @chennifer_jen looking at the role of NSAIDs in #COVID19. NSAIDs dampen the cytokine and antibody response to SARS-CoV-2 infection @ASMicrobiology @JVirology @Yale_LabMed @StephanieEisen @YaleIBIO 1/n jvi.asm.org/content/early/… Early in the pandemic it was suggested NSAIDs could be dangerous in COVID patients by increasing ACE2 expression and thus SARS-CoV-2 replication. Infection does increase expression of the NSAID target PTGS2 (COX-2) 2/n