Neuroethicists have theorized that closed-loop brain devices that sense+modulate could alter personality & sense of self. Our team is the 1st to ask patients with such implants. Their stories don’t support this concern, but reveal novel ones.🧵 1/8

🔓: tandfonline.com/doi/full/10.10… We studied patients receiving responsive neurostimulation for refractory epilepsy. This is the first "closed-loop" brain modulation system in routine clinical practice. Patients were recruited before surgery, observed at clinic visits and interviewed over 1y post-op. 2/8

Been digging into #aducanumab data, thinking about how to advise my patients & their caregivers when they ask me, keeping in mind shared decision-making and that these are individual decisions. Would be grateful for feedback/corrections: 1/7 “Some colleagues I respect say they won’t prescribe this drug. I haven’t made that decision, but as of now I don’t recommend it to anyone. I do want you to make the choice that is right for you, so if you still want to try after we talk then we can discuss how to do that.” 2/7