Glycoscientist @theNCFG Harvard Medical School-BIDMC
🧪 Chemical Biologist
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Jul 1, 2020 • 5 tweets • 3 min read
Proud to share our latest publication which shows how to synthesize a library of #glycopeptides at microgram scale in a parallel and cost effective manner published in @CellChemBiol cell.com/cell-chemical-…
Collaboration between @theNCFG@NPohl_Group & @BoyceLab #glycotime
The method is based on SPOT synthesis technique (classically used to produce non-glycosylated peptides), which we modified to help with special conditions required for glycoamino acids (which are more fragile). We also developed a biopsy sampling technique to monitor reactions.