ID physician, GH Director and Associate Professor @CUDeptMedicine @CUAnschutz | @UnivalleCol alumnus | Editor-in-Chief @TAInfDis | Editor @PLOSGPH | 🇨🇴🇺🇸
Aug 28, 2022 • 4 tweets • 2 min read
1/ What are the proinflammatory cytokine levels during sepsis? Are they a lot?
Special kudos to the matchless and brilliant @AmalGharamti for leading this work
sciencedirect.com/science/articl…2/ The pooled estimated mean TNFα concentration in sepsis patients was 58.4 pg/ml, and 5.5 pg/ml in healthy persons.
A TNF-α cutoff level ≥14.7 pg/mL separated sepsis patients from healthy persons with a sensitivity of 82.6%, and a specificity of 91.7%
May 31, 2019 • 9 tweets • 4 min read
1/ Why tuberculosis has a preferential apical localization?
Is it the host? Is it the pathogen?
To answer this question, let’s review some cool stuff #MedTwitter#IDTwitter#IDMedEd#IDDailyPearl
Follow the thread 2/ Arnold Rich stated: “There is no more puzzling circumstance in the pathogenesis of pulmonary tuberculosis […] than the peculiar fact that in the adult the disease begins almost invariably in the upper portion of the upper lobe“ ncbi.nlm.nih.gov/pubmed/6839825