MD, PhD, Professor of Medicine and Co-Director, Comprehensive Breast
Cancer Center, University of Pittsburgh Cancer Institute. Pirates/Steelers/Pens fan
(1/8) Assume for a minute that what is going on is that the virus is hijacking autophagy pathways in cells to live and to thrive. We can discuss the support for this hypothesis at length but look at the @NEJM yesterday.
(2/8) The genes expressed in COVID-19 lung are in a large part related to autophagy (nejm.org/doi/pdf/10.105…), and increased neovascularization is a sign of autophagy.
