Cristen Willer, PhD Profile picture
Science/genetics/health. Mom of 5 + a black lab. Canadian/British/American
May 31, 2022 22 tweets 7 min read
Did you know that Albert Einstein and Lucille Ball died of the same condition?

They both died of a ruptured abdominal aortic aneurysm.

We (@umichCVC, UPenn, @Stanford, @uniofleicester, @otago & more) have just published some new research into this deadly disease. A 🧵 The research preprint, with statistical analyses led by @TanmoyRoychow13 with Derek Klarin @MGLevin, collaborating with talented physician-scientists led by @damrauer with Phil Tsao, @Matt_J_Bown, Greg Jones, the Icelandic team @hilmaholm, et al.
medrxiv.org/content/10.110…
Mar 23, 2022 7 tweets 3 min read
If you see saddlepoint approximation used in genomics, @weizhouw introduced the concept to fellow @umich grad student @ellenmschmidt ~2012/2013 when we developed GREGOR - a method for assessing significance of enrichment of overlap between a genomic feature and GWAS hits This allowed us to avoid deep permutation to estimate really small (significant) p-values
Sep 25, 2020 7 tweets 3 min read
Science has a history of treating Black Americans and other minority ancestry groups badly. We, as genetics scientists, are working hard to make it right & ensure research also benefits ancestry minorities. a thread #BlackLivesMatter #blackinstem #IndigenousLivesMatter To do that, we are asking and inviting minority ancestry groups to join genetics research studies (that also include majority ancestry groups fyi). We are dedicated to (and good at) protecting confidentiality and ensuring anonymity. 2/6