To counter the confusion between infection and disease, here's a thread on vaccines in the time of covid: 1) Vaccines are designed to prevent disease (symptoms). They are authorized and used based on their ability to prevent people from getting sick.
2) For some pathogens, including the COVID virus, people can become infected and pass the germ to others before they have symptoms/disease, or without ever having symptoms. 3) Ideally, we want vaccines to prevent disease and the infection itself so it can’t be passed to others.
Mar 21, 2020 • 5 tweets • 4 min read
A number of media reports this week on potential treatments for #COVIDー19. @WHO is tracking these developments and will update our treatment guidelines if any evidence emerges. Right now, what is needed are high quality #RCTs@JeremyFarrar @ICMRDELHI@Chikwe_I@jarottingen@MRCza
The @WHO#Solidarity trial will test chloroquine or HCQ, lopinavir/ritonavir with and without interferon beta, remdesivir versus Standard of care in many countries round the world, in order to generate robust evidence on mortality and hospitalization of #COVIDー19 patients