Gus Hamilton Profile picture
Infection, bugs, and how to survive them. Academic infection doctor and researcher.
Feb 12 8 tweets 2 min read
Wow, that Cochrane review on nurse vs doctors is actually REMARKABLY bad. So, it's obviously an interesting question, and I was totally suprised to see there have been 19 RCTs comparing mortality between nurses and doctors (!). And the reported CI is tight RR 1.03 (0.87 to 1.21)+ So that seemed totally odd. I would have seen those trials. So I have a look. Wow. They are TOTALLY disparate. NICU care. ART in Uganda. Lung cancer follow up. Diabetes clinic. INTRAVITREAL EYE INECTION! Do we think that these are comparable and meta-analysable in any way?! + Image
Aug 16, 2020 17 tweets 11 min read
Proud to present our follow up data on our COVID-19 DISCOVER cohort here in @ResearchNBT @NorthBristolNHS @BristolARU . Important implications for #LongCovid, follow up, and policy makers (@BTSrespiratory).

medrxiv.org/content/10.110… Image We prospectively recruited and followed up in-person patients with COVID-19 in Bristol, UK. Demographics and CONSORT diagram below. Nearly all agreed to attend. In clinic, we performed lung function, QoL scores, symptoms cores, and a CXR. ImageImage
Jul 5, 2020 11 tweets 5 min read
Have you had an antibody test? Were you convinced you had COVID-19 - but it was negative? Our new study might help. In this study (again - at @NorthBristolNHS - we look at the performance of one of the commercial, PHE approved Abbott Architect tests 1/n

medrxiv.org/content/10.110… PHE approved this assay based on internal validation (bit.ly/31KoB3t). They used 96 PCR positive patient samples and 760 negative samples, and found the test was really unlikely to have false positives ("highly specific") - only 2/760 true neg samples were positive 2/n