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Marc Scherlinger Profile picture
Marc Scherlinger
@m_scherlinger
MD. PhD, 🇫🇷 young rheumatologist / clinical & translational science researcher. Focus : immunology, systemic lupus, autoimmunity, Treg cells & platelets
Jan 27, 2023 • 7 tweets • 4 min read
Thrilled to share our latest article in @NaturePortfolio Reviews Immunology exploring the role of platelets in #immune mediated inflammatory diseases such as #SLE. Open access link 🔓 rdcu.be/c4ijW.
A thread In autoimmune & inflammatory diseases, platelets get activated in response to circulating autoAbs (directly or through FcGR2A binding), soluble factors such as DAMPs or infectious agents (ie through platelet TLR7). Platelet activation often follows disease activity -> biomarker