Discover and read the best of Twitter Threads about #immune

Most recents (24)

(start string) Nineteen yrs ago, a truck-bomb with 1-tn TNT changed my life. In the #UN office where I worked in #Iraq, it killed my spouse #Sergio and 21 friends. ‘Til today, no prosecutor or court ever gave us answers: why? B/c the #UN is #immune from prosecution
Ironically,#Sergio was #UN #HumanRights top man.Bomb survivors would like to know why immunity was never waived to bring justice. We are not alone:many withstand #abuse from international organizations’ #abuseofimmunity. Read my story in thread:
Following the impact of #Netflix ‘s movie #SergioNetflix, wanted to share a little about who #SergioVieiradeMello really was but above all, narrate what really happened after 2003 #Baghdad attack.We were a family when the bomb went off
Read 20 tweets
Thread 🧵👇:
After so many years of work and as a post Epstein-Barr virus infection #MECFS sufferer it makes me really happy that they have put our article on the cover of the August issue of Pathogens journal 👉:mdpi.com/2076-0817/11/8
(1/)
Until recently nobody talked about post-viral syndromes (actually they should be called chronic infectious syndromes) and they left all of us patients isolated both at a health and social level. Unfortunately it took another virus like #SARSCoV2 to show us how viruses are ...(2/)
...capable of developing chronic diseases like #LongCovid . It is curious that for bacterial infections we use antibiotics but for viral infections we leave it to our immune system to manage to control it. This must change. (3/)
Read 15 tweets
#2 B-COMPLEX/MULTI VITAMIN. Buy a liposomal or other form that increases bio-availability. Take 1 capsule w/Breakfast and Lunch. If you have stomach upset, try sublingual (under tongue) EZ Melt B-Complex in AM & Multi w/iron for Dinner. amazon.com/Liposomal-Meth…
#3 OMEGA 3s. Fish Oil, Krill Oil, Algae Oil are all good sources of Omega 3. Be careful the EPA/DHA ratio. EPA helps with inflammation/DHA helps with cognition. You need both! Opt for a 1:1 or 2:1 ratio of DHA to EPA (2:1 ratio eg. 800 DHA/400EPA) amazon.com/3Care-Concentr…
Read 93 tweets
This is the most straightforward explanation for chronic symptoms in at least a subset of #LongCovid patients. Partly b/c if the #virus is still present its activity can directly contribute to other phenomena also being documented in LongCovid
2/ Persistence of #SARS-CoV-2 in tissue could lead to shedding of spike protein into blood, which can catalyze the ongoing formation of microclots and hyperactivated platelets
3/ Persistence of SARS-CoV-2 can lead to ongoing downregulation of interferon and/or T cell signaling by the virus, creating an optimal atmosphere for activation of EBV or other #pathogens normally controlled by such immunity
Read 10 tweets
🧵12 scientific Twitter accounts you should go follow for the latest updates on #GutMicrobiome-host interaction research: 🦠👩‍🔬🧪⬇️

#aging #immune #nutrition #probiotics #brain #SciComm
1/12. @bykriscampbell - Kristina Campbell, MSc, is a #SciComm extraordinaire. Her tweets give excellent summaries of cutting edge #GutMicrobiome-host publications primarily #FMT #probiotics and #Disease
2/12. @john_damianosMD - Dr. John Damianos tweets about all things #Microbes and #Medicine. We're talking #Probiotics, #IBD, and more, from the prospective of a clinician.
Read 18 tweets
It almost looks as though jabs don't work.

It almost looks as though a weakened innate #immune response may be occurring in those jabbed.

As countries begin to backpedal, #Canada presses on w/ #booster uptake & #passports.

Canada:
1 jab: 83.75%
2 jabs: 77.94%
3 jabs: 37.31%
Adverse event reports (vaccine #injuries) up to & including Jan 21 2022: 35,211

Of these, 7,526 categorized as serious. (21%).

An event is serious if it:
-results in death
-is life-threatening
-requires hospitalization
-results in disability, congenital anomaly/birth defect
Deaths WITH #Covid19 up to & including Jan 28, 2022:

Age 0-19: 27
Age 20-29: 97
Age 30-39: 239
Age 40-49: 533

Reported/accepted "vaccine" adverse events (injuries) up to & including Jan 21, 2022 (35,211 total):

Age 5-17: 1,335
Age 18-29: 4,461
Age 30-39: 5,809
Age 40-49: 6,715
Read 3 tweets
I want to put this study on everyone's radar b/c I think it's a genuinely cool opportunity for people/patients to get high-quality data on their #SARS-C0V-2 #immune status over time👇 (I have no financial ties to the company).
2/ To be more clear about what the study involves, the @serimmune team will assess each subjects’ individual immune response to SARS-CoV-2 from both natural #infection and #vaccination for up to 5 years.
3/ If you register for the study, Serimmune will send you a sample collection kit that allows you to collect your blood at home. Then you simply mail the sample to their lab using the pre-paid envelope provided.
Read 6 tweets
1/14 🆕 🚨Accelerated article on #breastcancer just out in @nature! #bcsm

We asked:
1️⃣ What drives response to #chemotherapy in #breast #cancer
2️⃣ Can we use #machinelearning to predict response to chemotherapy❓

Link: nature.com/articles/s4158…

A 🧵👇👇👇 @OncoAlert
2/14 We are unable to #predict #response to treatment in clinic…

✅Good response ➡️treatment very effective ➡️better survival
❌Poorer response ➡️treatment less effective ➡️worse survival

Being able to forecast response would be a landmark advance!
3/14 We ran a study in women with #breastcancer @CUH_NHS+@CRUK_CI:
1️⃣who had a #cancer biopsy (which we analysed)
2️⃣received 18 weeks of chemo+/-targeted therapy
3️⃣had surgery (and we measured how much cancer remained)

We associated PRE-therapy profiles↔️POST-therapy response👇
Read 14 tweets
"I am convinced that immunizing young #children [] will lead to a tsunami of #autoimmune diseases." - Dr Geert Vanden Bossche, virologist

Don't think for 1 sec. that the #pharmaceutical industry is unaware of the implications as outlined by V. Bossche.

#Immunity-As-A-Service
"We cannot, we should not, under NO condition, vaccinate any child." - Dr Geert Vanden Bossche, #virologist

COVID-19 Vaccine Risks in #children - Geert Vanden Bossche speaks

Full presentation:

April 10, 2019: "Why Are #Autoimmune Diseases on the Rise?"

"It’s not so much our cleanliness but our increasingly #industrial lifestyle that is blocking the intake of these important #microorganisms."

elemental.medium.com/autoimmunity-i…
Read 7 tweets
1/ Excited to share how T cell therapies kill #leukemia!! multi-omics + new #computational #singlecell tools for longitudinal analysis 👉unexpected answer! cell.com/cell-reports/f…

*👏* @elhamazizi! 🙏 @dpeer Cathy Wu @MDAndersonNews @CPRITTexas @ColumbiaBME @sloan_kettering
2/ We studied donor lymphocyte infusion (DLI) - an #Immunotherapy for relapsed #leukemia after #BMT & the #og of #celltherapy. Previously, we showed DLI reversed T cell exhaustion - but didn't know why/how/which T cells were responsible...
ashpublications.org/blood/article/…
3/ To address these ?'s, we modeled intraleukemic T cell dynamics by integrating longitudinal, multimodal data from ~100K T cells (!) during response (R) or resistance (NR: nonresponder) to DLI.
Read 18 tweets
I'm excited to share with you our recent @biorxivpreprint where we demonstrate that @vaxart mucosal Ad5 #SARSCoV2 vaccines not only protected against disease but also reduced transmission after post-#vaccination #SARSCoV2 infection in a hamster model. biorxiv.org/content/10.110… A🧵/
If you follow me, you are well aware of my obsession w/ #mucosalimmunity.😂Protection generated at mucosal surfaces is at the crux of one of the biggest questions we need to answer during this unique phase of the #pandemic - How do we decrease #SARSCoV2 #transmission to others.
Considering most of the world is unimmunized (including most kids <12), the possibility that a vaccinated individual with a post-vaccination infection (aka #breakthrough) can spread #SARSCoV2 is a public health risk. We need #transmissionblocking strategies.
Read 19 tweets
In our recent review on #LongCovid/PASC we bring up the possibility that dysbiosis or imbalance of host #microbiome communities (in ecosytems such as the gut, lungs, or oral cavity) might contribute to at least some LongCovid symptoms: frontiersin.org/articles/10.33…
2/ More specifically immune dysregulation driven by #SARS-CoV-2 might allow pathobionts (bacteria capable of both commensal + virulent acitivty) in the gut, mouth, or other body sites to collectively shift towards a state of imbalance + pro-inflammatory gene/metabolite expression
3/ Conversely, b/c composition + activity of the microbiome can influence host susceptibility and ongoing control of #viral pathogens, exisiting microbiome dysbiosis in a range of body sites may serve as a form of predisposition to LongCovid
Read 11 tweets
Brand New Data #keto #immune

#keto diet improves adaptive immunity through immunometabolic reprogramming without up regulating innate immunity

Basically: stronger immune system with less inflammation 🔥 embopress.org/doi/epdf/10.15…
2/ #Ketogenic diet could also prove to be a valuable measure in the
threatening situation of the current #COVID-19 pandemic” ya, no kidding... in more ways than one
3/ “These new immunological aspects of KD might contribute to the modern concept of metabolic therapy of cancer (Seyfried et al, 2017, 2020). KD not only targets the Warburg effect, but could also
strengthen anti-tumor immunity (Ferrere et al, 2021).” .@Sam_Apple1
#sugar #cancer
Read 3 tweets
Preprint reports elevated serum inflammatory cytokine profile in #LongCovid subjects. Worth noting that an ongoing immune response towards persistent viral reservoirs of #SARS-CoV-2 and/or antigen could explain the findings: medrxiv.org/content/10.110…
2/ So the findings underscore the need to do studies that obtain tissue (via surgery or biopsy if possible) to search for #SARS-CoV-2/antigen in #LongCovid patients. Similar to what this team did (and found viral RNA/antigen in multiple tissue types!): gut.bmj.com/content/early/…
3/ Studying both the LongCovid immune response AND possible #viral reservoirs is very important for LongCovid patients to get the best treatment. If you assume the #immune response alone is the problem, standard of care could become immunosuppressive drugs
Read 4 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
As we learn more about #COVIDvaccine #immune response in people w/ #immunedisorders, remember that not all #immunodeficiencies are created equal. You might see in the news claims about #vaccines not working in the #immunocompromised, but that's not always true. A 🧵
One of the earliest articles showed 15% of #transplant patients were Ab positive after dose 1. This increased to 54% after dose 2, but varied by medications being taken. bit.ly/3x00nyA and bit.ly/3cmfria
In #cancer patients, Ab response varied by type of cancer. Two studies showed 92-95% w/ solid tumors were Ab pos after the 2nd dose. One showed only 60% w/ hematological cancers were positive. bit.ly/34LseXc (both) bit.ly/3chrU6s (solid tumor only)
Read 7 tweets
Ultimate victims of media induced fear & politically correct #posturing will be our #children. "hygiene hypothesis: "when exposure to parasites, bacteria, & #viruses is limited early in life, children face a greater chance of [] allergies, asthma, & other #autoimmune diseases..." Image
Dec 10, 2020, Nature: "'#Children are very much adapted to respond — & very well equipped to respond — to new #viruses,' [] even when they are infected w/ #SARSCoV2, children are most likely to experience #mild or #asymptomatic illness." Image
"These children’s #immune systems see the #virus & mounts this really quick & effective immune response that shuts it down, before it has a chance to replicate to the point that it comes up positive on the swab diagnostic test",

Natural #Immunity is not a conspiracy theory.
Read 12 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
In the latest issue! Be sure to explore this exciting research about #SARSCoV2 variants and their #escape from #immune response
bit.ly/3e2QxoP

For all @CellPressNews #coronavirus research and commentary, visit cell.com/2019-nCOV
#COVID19
🔽🔽🔽
Mutations in the #SARSCoV2 spike #protein result in tighter binding to the #ACE2 receptor and allow escape from monoclonal #antibody neutralization. Online now! @UniofOxford
bit.ly/3nzukSI
The 501Y.V2 #variant of #SARSCoV2 exhibits resistance to neutralization from monoclonal #antibodies and sera from convalescent as well as #immunized individuals
bit.ly/3xxMrNe
Read 5 tweets
1/ A: Celebrate the mild #flu season & take what we have learned this year to inform future behavior. Harmful germs are not going away. 🦠 Illness from bacteria & viruses that make us sick do not “strengthen” the #immune system & contribute to significant complications & death. Image
2/ The lack of infectious illnesses will not #weaken your #immunesystem. Public health measures to combat #COVID19 including social distancing, masks, & extra hand washing greatly reduced the incidence of some bad microbes that cause common infectious illnesses such as the flu.
3/ More than 15,000 US deaths attributed to the #flu were averted this year. Other common viruses, like rhinoviruses, did not decrease as consistently. #Bacteria & #viruses that cause illness will continue to exist. go.nature.com/2OxkiUv
Read 9 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
#Cassandra: #SARS1 bound "Spikes" to Human #ACE2 receptors ONLY. Those are rare in healthy people.

In #SARS2 & #MUTANTS (#COVID19) they now bind ALSO to #Furin receptors, as in #HIV/#AIDS & #Ebola, which makes it 1000 x as #Infectuous:

— RT World News rt.com/news/481837-co…
#Cassandra: January 2020 article:

Uncanny similarity of 4 unique #Inserts in the 2019-nCoV (SARS-CoV-2) spike protein to #HIV1 (AIDS) #Gp120 and #Gag:

->biorxiv.org/content/10.110…
#Cassandra: Article March 2020.

#SARS_CoV_2 (COVID19) is NOT Natural !

#Czech molecular biologist, Dr. Soňa Peková explains in layman terms that #COVID19 virus originates from a lab, and the Americans try to refute it (Updated):

dimsumdaily.hk/czech-molecula… via @dimsum Daily
Read 10 tweets
Once Upon a Time: an RNA vaccine! How does the #vaccine work, and what happens if the #coronavirus tries to attack a vaccinated person? @helsinkiuni @HelsinkiOne @LifeSciHelsinki PDF: bit.ly/coronavacc #COVID19 #COVID19Vaccine #SARSCoV2 ImageImage
For a bit more #immunology: Once Upon a Time - #immunity! How does our marvellous adaptive #immune system work? @helsinkiuni @HelsinkiOne @LifeSciHelsinki PDF: bit.ly/comic_immunity ImageImage
Small (but important) correction to Immunity Episode One! The T cells in this story actually are Tim, Tanya and Tucker (not Tobias and Tiffany). They all look so similar that I always get confused! Image
Read 4 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!