Discover and read the best of Twitter Threads about #immune

Most recents (16)

Vi racconto la storia di un giorno in #pandemia. Perché anche un tweet può diventare #virale.
Una ragazzina che si dichiara contraria ai #vaccini. Sicura mi dice: “Si informi”. Nasce da lì la voglia di dirle: “Ma tu che hai evitato tutte le #malattie dell’infanzia, cosa sai? Image
Che ne sai dei bambini del passato, del #morbillo, della #pertosse, fino alla #poliomielite?
Li hai visti i bambini zoppicanti, in carrozzina, nei polmoni d’acciaio? O quelli butterati dal #vaiolo? Li hai mai visti i #lebbrosi? I volti deturpati, le mani che perdono pezzi? Image
Scrivo un tweet e lui fa lo #spillover e dai miei pensieri rimbalza in quelli di tanti altri. Ogni tweet è un potenziale #virus, ma a volte non trova popolazione infettabile. A volte avviene che pochi si infettino e muore lì, come #ebola in un villaggio nella giungla di internet Image
Read 12 tweets
1/ The problem with Myalgic Encephalomyeltis/Chronic Fatigue Syndrome #MECFS is that it seems so ridiculous that exercise could actually make patients worse

How can exercise be so bad for #pwME but so good for almost every other serious illness?

THREAD
2/ New study by @4WorkWell @sunsopeningband et al shows that #MECFS patients have metabolic defects that cannot be explained by exercise phobias, deconditioning or 'illness beliefs'

#pwME have reduced oxygen consumption during exercise tests
buff.ly/2CXH6Hj
3/ #pwME have an impaired ability to increase their oxygen consumption during exercise

This is entirely different to every other disease we know including cardiovascular disease, lung disease, end-stage renal disease, hypertension & cystic fibrosis

…nslational-medicine.biomedcentral.com/articles/10.11…
Read 11 tweets
#CuratedTruth

"#Homoeopathy is a branch of universal #medicine based on the ‘principle of the like’ (Similia Similibus Curentur = Like treats Like) and in #minimum doses." .. I
It means that a #substance in a massive dose generates #pathological #symptomatology; has the possibility to #cure it, if applied in the #minimum doses obtained by #dilution and intense #agitation, in other words, #homoeopathic #succussion. .. II
#Homoeopathy is derived from a #Hippocratic #concept developed by the #German #physician, Samuel Hahnemann (1755–1843), with serially #diluted #medicines (1:9, 1:99, 1:999 and others) in water-ethanol vehicle alternating #dilution with #succussion. .. III
Read 28 tweets
Cool new study which found that a range of #pathogens (some capable of long-term persistence in tissue + #blood) upregulate expression of the cell surface protein CD47 in the host cells they infect as an #immune evasion strategy
2/ I fact, upregulation of CD47 is a very smart survival strategy by such pathogens, b/c it interferes w/ the host innate immune response that is normally supposed to identify, target and kill them!
3/ Specifically the team found that upregulation of CD47 by the pathogens under study slowed uptake of dead/#infected cells by the #immune system, including the downstream activity of #antigen presenting cells that are needed to recognize pathogens in the first place
Read 10 tweets
Daily Bookmarks to GAVNet 6/04/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/04/dai…

Graduate Student Solves Decades-Old Conway Knot Problem | Quanta Magazine

quantamagazine.org/graduate-stude…

#topology #Knot
What We Lose When We Assume People Are Bad : NPR

npr.org/2020/05/15/857…

#people #bad #SFI
Read 12 tweets
Daily Bookmarks to GAVNet 6/03/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/03/dai…

An interpretable mortality prediction model for COVID-19 patients | Nature Machine Intelligence

nature.com/articles/s4225…
#model #intelligence #machine #prediction #mortality
“Immune to Evidence”: How Dangerous Coronavirus Conspiracies Spread — ProPublica

propublica.org/article/immune…

#conspiracy #evidence #immune #spread
The public do not understand logarithmic graphs used to portray COVID-19 | LSE Covid-19

blogs.lse.ac.uk/covid19/2020/0…

#public #Graphics
Read 12 tweets
#JudyMikovits on #COVID19
"This is Project X"
XMRVs triggered by Sars-Cov2 & #5G both attacking red blood cells creating a severe immune overload response that the body can't handle.
It’s not sars cov 2 alone, there are other viruses involved incl' XMRVs
2/
It’s sars-cov2+XMRVs
The mouse cancer causing viruses which can affect every cell of the body through phosphate transporters XPR1
If you’ve got both of those then you’re dead
The trigger is if you get shot with sars cov 2 or ...
3/ ...radiation like #5G when 60MHZ separates the iron from the hemoglobin or glyphosate.
There are other things from the #environment that can cripple the #immune system. Your immune system has a latency period and we have shortened the latency period.
PROJECT X.
EngineeredCombo
Read 5 tweets
Thoughts on upcoming #COVID19 #serology tests:
This is actually quite a challenge! (#Diagnostics often involve a lot of complexities). There is a lot of pressure to roll these tests out, but they need to perform well, or we do more harm than good. #MicroRounds (A thread)
WHY we need these soon:
1. Contact tracing.
2. Can be used to test if a vaccine is working during a clinical trial (70 of them ongoing right now, I believe)
3. Inform public policy makers about rate of asymptomatic cases + previous infections/exposures =informed decision making
How is developing a #PCR different than developing a #serology test?
1. #PCR tests detect viral RNA/DNA (in this case RNA) and can be pretty straight-forward in terms of development
2. #Serology relies on knowing about the #SARSCoV2 structure and how the human body responds.
Read 13 tweets
So, yesterday I shared with you a presentation I made on #immune function & exercise, and then on detraining & fitness during #lockdown. How much, how fast, how to prevent etc? Here’s the link again to watch it n full, and a short thread to summarise: (1/)
(2/) To begin, there are a few times in exercise physiology (& other domains, I’m sure) where you hear about a “J-Curve” model.
Exercise & immune function is a classic J-Curve: Too little = bad, too much = bad, but in between = lower infection risk. Fitness is a health benefit
(3/) Then you have the “Open Window hypothesis”, which is to the J-curve what Bonnie was to Clyde. Idea is that there’s a window after intense and/or prolonged exercise where you’re more vulnerable to infection. Diagram shows changes from hard (marathon) & easy (walk) exercise
Read 22 tweets
This study found that Epstein Barr #Virus (EBV) IgM antibody seropositive #COVID-19 patients had a 3.09-fold increased risk of fever compared to EBV seronegative patients. Inflammatory markers like C-reactive protein were also higher in the EBV+ patients: researchsquare.com/article/rs-215…
2/ The study is a small, but good example of the how already-acquired persistent #pathogens can influence how a person responds to a new #infection: the existing pathogen(s) might cause additional symptoms or influence how the #immune system can respond to the new infection
3/ For example this study found that persistent Cytomegalovirus (CMV) infection caused ~10% of all T cells in CMV+ individuals to be directed against that virus. Could harboring CMV then change how the adaptive immune system responds to COVID-19?: ncbi.nlm.nih.gov/pmc/articles/P…
Read 10 tweets
MAR 24 #COVIDー19 #MDTHREAD 1: tinyurl.com/se479vy
TODAY's #US Numbers as of 10:58 AM
CASES 50,212 DEATHS 606..
#Recovered 333 (see Importance below)
By Rick Noack, Lateshia Beachum, Kim Bellware,
Marisa Iati, Siobhán O'Grady, Adam Taylor and
John Wagner
10:51 a.m. PDT
MAR24 #COVID19 #MDTHREAD 2: Here from my AM MD Threadlet.. SOMETHING POSITIVE about it all..
The Importance of our #RECOVERED
tinyurl.com/ty32gxb .. with #Immunologic data from @NAChristakis .. LINK in my TWEET 1.
Please read esp #Medicals who will understand. @maddow @CNN
MAR 24 #COVID19 #MDTHREAD 3: Here is link to Yesterdays's MAR 23 ...36 TWEET THREAD..

tinyurl.com/s2x2ffx
AND ICYMI: Last WED. March 18 #US NUMBERS...
Read 32 tweets
GREAT THREAD Sciencey but as an MD I appreciate that. Discusses studies already done that show, yes THOSE WHO #Recover from #SARSCov2 are #immune and have cleared virus from themselves. They can go back to work or better yet CARRY MESSAGES TO THE SICK tinyurl.com/refbs6p
GOT THAT @UnitedWay @ADL? I rec an Identity PINK (or other) Armband w ‘R’ or Angel, so Families and Hospitals will know they are safe with those not sick or sick. @SenAmyKlobuchar do you know DefCounsel #Goldman perhaps he would carry message to your husband. @RepAdamSchiff
SEE WE have a burgeoning Army of #RECOVERED .. Hopefully some will agree to be Compassionate and Help Others Not just selfishly go back to work or play. #GovCuomo the #NewRochelle and #ChristChurch clusters were early SB Many #Recovered. Read thread there is a test to prove it.
Read 6 tweets
(1/n) Delighted to share our work using #scRNAseq to explore the intersection between regeneration, development and #immune recognition in #cancer #metastasis online @NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague
nature.com/articles/s4159…
@NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague (2/n) human primary #lungcancer is characterized by the emergence of regenerative cell types, typically seen in response to lung injury, but showing striking lineage promiscuity (identity confused!)
@NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague (3/n) #metastasis exhibits a continuum of more primitive stem to epithelial progenitor states – driven in large part by key embryonic and lung-specifying transcription factors, SOX2 and SOX9.
Read 11 tweets
18 myths & misconceptions of Post-Exertional Malaise #PEM in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome #MECFS

#PEM (aka PENE, "flare" or “crash”) is seriously debilitating symptom caused by exercise

#SickNotWeak #SickNotTired #pwME #chronicillness #medtwitter #MedEd
1. #PEM is just tiredness

No

#pwME experience <pathological> fatigue after #exercise which can be long-lasting and includes debilitating fatigue, flu-like symptoms, cognitive impairment, #sleep disturbance

@PNASNews #MECFS #MyalgicE #MedEd #medtwitter
pnas.org/content/114/6/…
2. #PEM is not a real

No

“there exists no medical condition.. where exertion.. causes #immune/ inflammatory-related symptoms like sore throat, tender lymph nodes, or flu-like feelings, yet 60%.. of.. [#pwME].. reported these symptoms”

@PLOSONE #MECFS
dx.plos.org/10.1371/journa…
Read 20 tweets
I got to explain #GayPanic and #UselessLesbian to my pysch today 😂

These are terms I just learned (over the last few months myself) that described succinctly, what the heck is going on with my brain.

To unpack these terms, I'm going to start you with Sappho.
-
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“Sweet mother, I cannot weave –
slender Aphrodite has overcome me
with longing for a girl.” –Sappho

To everyone, we've almost all been in this feeling. (i cannot speak for Ace)
Someone we see or meet, and their presence just #dazzles us into #malfunction (however brief)

-
- it's a pretty common #human #feeling. (again, cannot speak for Ace, and that's ok, y'all are lovely :) )

now here's where #GayPanic sets in... we feel the feels...omg. wow.
and our brains go into... IS THIS DANGER????

I'm sorry to say, our panic does start there.
-
Read 17 tweets
1 - right, this is my 1st attempt at a long thread. I feel I’ve discovered something interesting & a penny has dropped! Some things #DeepState are doing doesn’t make sense on its own but when you put them together, it begins to fit. Happy reading!
2 - okay, here’s a thought... what’s #foodsafety ‘use by’ dates got to do with #chemtrails #GeoEngineering? Chemtrails would fall on everyone including the evil. I believe they only react with certain other chemicals; those in drugs popular with us non-elite...
3 - #ibuprofen (ans to physical pain) & depression drugs (and to psychological pain). Most of us covered! The aim of chemtrails it to react & weaken our #immune system while #vaccines reduce our #fertility as well as weaken us. @BillGates even admitted in a @bbc interview...
Read 10 tweets

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