Seena Fazel Profile picture
Prof of Forensic Psychiatry, Oxford University; researching adverse outcomes in mental illness, prisoner health, risk assessment for suicide and violence/crime.
Sep 28, 2023 12 tweets 4 min read
Focusing on one statistic, particularly PPV (positive predictive value=proportion classified as high risk at a cut off that have the outcome), should have no place in a reasoned/balanced discussion of suicide risk assessment. A range of performance measures is now standard. 🧵👇 In recommended PROBAST guidelines to assess bias risk, model calibration and discrimination ‘must’ be assessed. Cut-offs can follow - allow for testing of measures of classification, e.g. sensitivity, specificity, PPV and negative predictive value (NPV). pubmed.ncbi.nlm.nih.gov/30596875/
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Sep 20, 2023 17 tweets 8 min read
Our new paper!! Development and validation of a new prediction model for suicide risk in people who have self-harmed.
Very different to previous prediction tools - and directly addresses concerns by some experts and NICE.
#OA: 1/ mentalhealth.bmj.com/content/26/1/e…
Image 16M people self-harm/year - and suicide risk is 20x increased in the next yr (or 1 in 50-100 people). Current guidelines recommend intensive psychol treatments for all - not realistic for most health systems. Hence the need for possible risk stratification. See recent reviews👇.
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Jan 23, 2023 16 tweets 7 min read
New paper!! Examines a neglected population in the area of health and justice - people given community snetneces. What is contribution of psychiatric disorders to any and violent reoffending? Large population study (n=82k), sibling controls. Short 🧵👇thelancet.com/journals/lanpu… Despite community *sentences* being widely used, reoffending rates are not low. Recidivism rates in UK >25% over 1 yr. In many countries, >20% over 1-2 yrs. Figure 👇from 2019 review (and note higher rates in Norway than Ireland/Holland): journals.plos.org/plosone/articl… 2/
Nov 2, 2022 14 tweets 5 min read
New paper! Antipsychotics are widely prescribed in people with personality disorders. Using Danish population registers, we examined links between these medications and self-harm, suicide, and being charged with violent crimes? Short 🧵 @EBMentalHealth #OA Image Primary analysis was to use a within-individual design to test associations between those dispensed antipsychotics and adverse outcomes. This design examines outcome rates when someone is dispensed (i.e. prescribed and collected) meds compared to when they are not dispensed meds
May 19, 2022 8 tweets 3 min read
What effects do prisons have on repeat offending? Our new paper examines this across 44 Swedish prisons. V brief thread. Paper #OA: journals.plos.org/plosone/articl… 1/ Image We compared reoffending rates in people who were in different prisons at the same security level (between-individual), adjusting for measured confounds, and also examined repeat offending in the same person released from different prisons (within-individual). Two approaches. 2/ Image
Mar 11, 2021 8 tweets 4 min read
Our new paper examines associations between specific antipsychotics and a wide range of crime outcomes, incl. arrests and convictions for violent and drug-related offences. Analyses data on all prescriptions 2006-13 in Sweden. Some novel findings. #OA: cambridge.org/core/journals/… 1/ First, the overall pattern emerges that antipsychotics are associated with clear reductions in all crime outcomes. Shown in between-individual models (crime rates in people dispensed meds vs those not dispensed meds) - among the persons who were prescribed antipsychotics 2/