The current anti-Indian sentiment in America is nothing new. It’s a tired, recycled view. And as history shows, always a losing argument.

Anti-Irish
1840s–1850s
Portrayed as drunkards and troublemakers and racially inferior.
“No Irish Need Apply.”

Anti-Chinese
1870s–1880s
Viewed as job-stealers and blamed for economic woes, called a “Yellow Peril”
“Not a Chinaman’s chance.”

Anti-Jewish
Late 19th to mid-20th century
Stereotyped as greedy, controlling finance
"Gentiles only."

Anti-Italian
1900s–1920s Dismissed as anarchists, criminals, or racially “unfit”
“Wops, go home!”

Anti-German
1917–1918
Suspected of espionage and branded as enemies
“Don’t speak the Hun’s tongue!”

Anti-Mexican
1930s–1950, 2020s
Blamed for economic competition and social unrest
“Go back to Mexico”

Anti-Japanese
1940s
Deemed disloyal
"A Jap's a Jap"

Anti-Southeast Asian (Vietnamese, Cambodian, etc.)
1970s–1980s
Derided as dirty and burdens on society
"No more boat people!"

Anti-Arab
2001–2002
Cast as potential terrorists or extremists
"Go back to the Middle East where you belong.”

Anti-Indian
2024-2025
Portrayed as third world invaders, job stealers
[check twitter] Incredible example, from 1891

https://x.com/sethbannon/status/1969825988575170736

Perfect policy to incentivize American companies to open up offices overseas.

And that's exactly what the research shows they do 🧵

https://twitter.com/atrupar/status/1969154936496664887

2/ The study is by Wharton’s Britta Glennon. Published in Management Science and via the NBER. She links H‑1B records to the BEA census of U.S. multinationals to see how headcount shifts when visas get tight.

1/ From pacemakers to defibrillators to protease inhibitors to vaccines to clinical MRIs, the public has gotten enormous benefit from federally funded research at Harvard. Just a sampling… 2/ Cardiac pacemakers (1950s–60) came from federally funded research at Harvard: first external, then implantable devices, saving millions by maintaining steady heart rhythms.

1/ Is DOGE the most incompetent agency in American history? Let’s look at the evidence... 2/ DOGE, created by Trump and led by Elon Musk, aimed to slash “waste, fraud, & abuse.” Instead, it slashed public health programs, nuked safety oversight, and botched basic math. The receipts...

Plant-based cheeses just don't cut it: the cheeseburgers are gummy; the grilled cheeses stick to the teeth; the pizzas don’t have instagram-worthy cheese pulls.

Enter @Nobellfoods, who have engineered plants to efficiently and sustainably solve this. 🧵

fiftyyears.substack.com/p/nobell-foods Cow milk is a complex mixture of proteins and metabolites, many of which can only be created by mammals. The key ingredient that gives cheese its tasty, melty, and stretchy properties is a biomolecule that makes up about 80% of the protein in cow’s milk -- casein.

Election predictions thread.

Tldr: sanity restored after an ugly few weeks.

Biden wins, sweeping Clinton states + WI, MI, PA, AZ, NC (maybe FL + GA).

Trump declares victory on election night, using twisted logic like being up big in PA BEFORE mail in votes are counted.

1/ Trump will immediately claim vote counting needs to stop on election night (something that's literally never happened before but it's 2020, so...)

Trump team & GOP sue to stop counting (legitimate) mail in ballots in all swing states.

2/

In labs right now are researchers working on innovations that can cure disease, end malnutrition, fix the climate crisis, connect the world.

But scientific innovations don’t solve problems on their own. By default they end up published in a journal and that’s it. No impact. 1/ Ensuring scientific innovation actually reaches its full impact potential matters.

We’re talking brothers', sisters', mothers', fathers' lives saved.

Millions of children given a better life.

Clean air and clear skies.

Almost a billion people lifted out of poverty. 2/

Study in the Lancet finds that #COVID19 viral shedding can be UP TO 37 DAYS, with an average of 20 DAYS.

*Patients may still be contagious during that time*

VERY BIG DEAL because current guidelines recommend only a 14 day (2 week) isolation time. 1/n

thelancet.com/journals/lance… This means patients may remain contagious well after they're no longer symptomatic.

And it means current guidelines (14 day isolation) may lead to additional propagation post quarantine. 2/n

American Hospital Association "Best Guess Epidemiology" for #codiv19 over next 2 months:

96,000,000 infections
4,800,000 hospitalizations
1,900,000 ICU admissions
480,000 deaths

vs flu in 2019:

35,500,000 infections
490,600 hospitalizations
49,000 ICU admissions
34,200 deaths Source on American Hospital Association numbers:

businessinsider.com/presentation-u…

Source on flu stats:

cdc.gov/flu/about/burd…

There are 5 big changes since the old cleantech bust days:

1) broader definition of clean / climate tech
2) technical developments that make more things possible
3) employee preference changes
4) consumer preference changes
5) investor preference changes

Why now is different 👇 1st we've realized there are many good ways of attacking the climate crisis w/ tech. What was in the old days biofuels & renewable hardware is now: food tech, clean chemicals, transportation, renewable hardware & software, industrial decarbonization, etc 

Broader definition!

👇

🙌 @MemphisMeats has closed a $161M Series B! The future of food is bright indeed!

With this round they'll build the first U.S. production plant for cultivated meat. THIS IS HAPPENING and sooner than most thought.

Some thoughts on where we've been and where we go from here 👇 Memphis Meats is bringing needed innovation to an industry where the core technology hasn't changed much since we started domesticating animals over 4,000 years ago in Mesopotamia.

Not many industries are using the same technology as 4,000 years go!

👇

We want to create a revolving door VC firm.

We want founders to join our team, spend a few years helping support other founders, leave to start their next thing (we'll even put up the initial $$), and then we want them years later (succeed or fail) to come back.

Why? 👇 This is the only way to keep founder empathy high.

Everyone on the @fiftyyears team is a former founder, so we naturally have high empathy for the founder journey. But the more time we spend on the investing side, the more disconnected we'll be from the founder experience.

👇

Can finally share!

Portfolio company @astranis_space signed a very large contract to cover Alaska in internet from space. Exciting not only because the deal is worth tens of millions of $ but because internet access is a systemic good & 39% of Alaskans are underserved.

THREAD👇 Internet connectivity is the definition of impact infrastructure. Connecting more people boosts economic growth, reduces inequality, increases social cohesion, democratizes education, leads to better government & social services, & improves public health.

Let's examine each:

2/