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Yulong Li Lab Profile picture
Yulong Li Lab
@yulonglilab
Nov 9, 2022 • 6 tweets • 2 min read
1/6 PGE2 is one of the principal bioactive prostaglandins, critical signaling lipids implicated in body homeostais and pathegenic inflammatory response, yet its in vivo dynamics are largely unknown. #GRABsensors #Prostaglandins 2/6 Now we newly developed a fantastic GRAB-PGE2 sensor for monitoring PGE2 dynamics with high spatiotemporal resolution in vivo!
Mar 28, 2022 • 5 tweets • 2 min read
1/4 A toolkit of new GRAB fluorescent neuropeptide sensors from Li Lab! These sensors can detect neuropeptides at nanomolar concentration with a robust increase in fluorescence. #GRABSensors #Neuropeptide 2/4 GRAB-CRF1.0 reveals in vivo CRF dynamics in the cortex and hypothalamus induced by stressful experiences using fiber photometry and 2-photon imaging in mice.