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Recent
Mitochondrial findings in ME/CFS and Long COVID include altered fuel use, lower
energy efficiency, immune-cell energy stress, muscle-cell abnormalities and worse
muscle findings after PEM.
This thread breaks down what that means in simple language.
energy efficiency, immune-cell energy stress, muscle-cell abnormalities and worse
muscle findings after PEM.
This thread breaks down what that means in simple language.
The main idea is not "mitochondria are broken".
The research points more towards cells struggling to meet energy demand cleanly, especially during immune stress, muscle contraction or PEM.
The research points more towards cells struggling to meet energy demand cleanly, especially during immune stress, muscle contraction or PEM.
Mitochondria help cells turn fuel and oxygen into usable energy.
They also help control immune signalling, cell stress and inflammation.
So mitochondrial findings can reflect energy strain, immune activation or both.
They also help control immune signalling, cell stress and inflammation.
So mitochondrial findings can reflect energy strain, immune activation or both.
The Art in Pixels is an online art gallery dedicated to preserving and sharing the world’s great public domain paintings. The collection brings together hundreds of renowned artists, carefully organized for exploration, study, and inspiration.
theartinpixels.com
theartinpixels.com
Anthony van Dyck was born in 1599 in Antwerp and became one of the most influential portrait painters of the Baroque era. He trained under Peter Paul Rubens, whose dynamic style and rich color left a lasting impression on his early work.
theartinpixels.com/artists/anthon…
theartinpixels.com/artists/anthon…
Jan Steen was born in 1626 in Leiden, the Netherlands, and became one of the most distinctive genre painters of the Dutch Golden Age.
theartinpixels.com/artists/jan-st…
theartinpixels.com/artists/jan-st…
🏭 Inside AgentCity #11 — MissionFactory
So far, we’ve seen how AgentCity gives agents identities, reputation, economic accountability and a wider system of rules.
But eventually, the agents need to actually do something.
One agent needs work done.
Another agrees to provide the service.
Payment needs to be secured.
Collateral may need to be locked.
And the agreement needs somewhere to live on-chain.
That’s where MissionFactory comes in.
📍 Testnet Contract 0x50b67B8B77bFf678cA7bC78F7F080C249790F8Bb
👇
So far, we’ve seen how AgentCity gives agents identities, reputation, economic accountability and a wider system of rules.
But eventually, the agents need to actually do something.
One agent needs work done.
Another agrees to provide the service.
Payment needs to be secured.
Collateral may need to be locked.
And the agreement needs somewhere to live on-chain.
That’s where MissionFactory comes in.
📍 Testnet Contract 0x50b67B8B77bFf678cA7bC78F7F080C249790F8Bb
👇
1/ MissionFactory is where a new job begins
Think of a Mission as an on-chain job or service agreement.
The client agent is the customer requesting the work.
The provider agent is the worker or service provider carrying it out.
MissionFactory takes the agreement between them and turns it into a real on-chain Mission.
But it doesn’t simply deploy a contract and hope for the best.
👇
Think of a Mission as an on-chain job or service agreement.
The client agent is the customer requesting the work.
The provider agent is the worker or service provider carrying it out.
MissionFactory takes the agreement between them and turns it into a real on-chain Mission.
But it doesn’t simply deploy a contract and hope for the best.
👇
2/ Before creating anything, it checks the participants
Both agents must already exist and be active.
The agreement must identify the correct client and provider.
The same agreement can’t simply be reused again.
And both sides must have authorised the terms.
In simple English:
MissionFactory checks that the customer and provider are valid, that they agreed to the same job, and that the agreement hasn’t already been used.
👇
Both agents must already exist and be active.
The agreement must identify the correct client and provider.
The same agreement can’t simply be reused again.
And both sides must have authorised the terms.
In simple English:
MissionFactory checks that the customer and provider are valid, that they agreed to the same job, and that the agreement hasn’t already been used.
👇
‼️FINALLY, PROGRESS IN FLORIDA! YOU DID THIS!
After years of report after report and video after video exposing the Muslim Brotherhood’s operations in Tampa, Orlando, and across the state, Florida leadership is finally taking real action.
RAIR Foundation USA has been documenting how this network has been operating through schools and communities built with public money.
We exposed Magda Elkadi Saleh - the daughter of the former head of the Muslim Brotherhood in America - and the connected schools collecting millions in taxpayer-funded school vouchers.
We showed CAIR’s influence inside those schools and the growing enclaves being created with public resources.
We even went to Congress twice to present the evidence directly.
Because of that persistent work and YOUR relentless voices amplifying it nonstop, leadership is finally starting to listen. YOU DID THAT!
Governor DeSantis’ new law, which took effect July 1, designates the Muslim Brotherhood and CAIR as terrorist organizations and cuts off school choice funding to networks tied to them.
This is real progress.
But do not let the pressure up. If we go quiet, the politicians will stop acting.
Thank you to everyone who shared our reports and refused to stay silent. Thank you for moving to ACTION and making phone calls, sending letters, tagging your leaders social media - it is ALL making a major difference!
Red states are moving - let’s keep the momentum going.
After years of report after report and video after video exposing the Muslim Brotherhood’s operations in Tampa, Orlando, and across the state, Florida leadership is finally taking real action.
RAIR Foundation USA has been documenting how this network has been operating through schools and communities built with public money.
We exposed Magda Elkadi Saleh - the daughter of the former head of the Muslim Brotherhood in America - and the connected schools collecting millions in taxpayer-funded school vouchers.
We showed CAIR’s influence inside those schools and the growing enclaves being created with public resources.
We even went to Congress twice to present the evidence directly.
Because of that persistent work and YOUR relentless voices amplifying it nonstop, leadership is finally starting to listen. YOU DID THAT!
Governor DeSantis’ new law, which took effect July 1, designates the Muslim Brotherhood and CAIR as terrorist organizations and cuts off school choice funding to networks tied to them.
This is real progress.
But do not let the pressure up. If we go quiet, the politicians will stop acting.
Thank you to everyone who shared our reports and refused to stay silent. Thank you for moving to ACTION and making phone calls, sending letters, tagging your leaders social media - it is ALL making a major difference!
Red states are moving - let’s keep the momentum going.
Florida’s Muslim Brotherhood Dynasty Exposed: How Magda Elkadi Saleh Is Building Sharia Institutions With Taxpayer Funds rairfoundation.com/floridas-musli…
FLORIDA ALERT: Newly Uncovered Muslim Brotherhood Origins of Magda Elkadi Saleh's Family - and the Civilization Jihad Unfolding in Tampa rairfoundation.com/florida-alert-…
The employment tribunal of Tempest v DEFRA and Rural Payments Agency continues today, 7 July. Expected start time, not before 10 am.
Our previous reporting, background information on the case, witness statements (after witnesses are sworn), opening notes from counsel and other relevant documents can be found on our Substack.
open.substack.com/pub/tribunaltw…
open.substack.com/pub/tribunaltw…
Tempest (the claimant or C) is claiming discrimination, harassment and/or victimisation on grounds of gender reassignment. Central to the claim is the Sex Equality and Equity Network in the Civil Service (SEEN or IP). SEEN has been granted right to intervene.
1/
@AP portrays Hamas' announcement that it's dissolving its Gaza government as a potentially positive step.
But the story omits key context that makes the announcement far less meaningful. 🧵
@AP portrays Hamas' announcement that it's dissolving its Gaza government as a potentially positive step.
But the story omits key context that makes the announcement far less meaningful. 🧵
2/
AP writes that Hamas "did not say whether it planned" to disarm, leaving the impression the question remains open.
But Hamas has already made its position clear, repeatedly and publicly rejecting disarmament.
aljazeera.com/news/2026/2/8/…
AP writes that Hamas "did not say whether it planned" to disarm, leaving the impression the question remains open.
But Hamas has already made its position clear, repeatedly and publicly rejecting disarmament.
aljazeera.com/news/2026/2/8/…
3/
Likewise, stating Hamas "has insisted on implementing the first phase before moving to discuss its weapons" again leaves readers with the impression Hamas is merely delaying talks, rather than outright rejecting disarmament.
Likewise, stating Hamas "has insisted on implementing the first phase before moving to discuss its weapons" again leaves readers with the impression Hamas is merely delaying talks, rather than outright rejecting disarmament.
1/ Ukraine's drone campaign is leading not only to fuel shortages but also political recriminations in Russia. The attack on the Omsk oil refinery yesterday is prompting increasingly harsh condemnations of Russia's government by Russian warbloggers. ⬇️
2/ 'Older than Edda' is outraged at the attack's success:
"Drone debris has reached Omsk, and hostile channels are distributing a defamatory video claiming it landed and caused a fire at a plant."
"Drone debris has reached Omsk, and hostile channels are distributing a defamatory video claiming it landed and caused a fire at a plant."
3/ "I don't want to be outraged yet again by the fact that several drones fly across the country for many hours and manage to hit something with drone debris."
Like many others, Sergey Kolayashnikov complains that it demonstrates Russian weakness:
Like many others, Sergey Kolayashnikov complains that it demonstrates Russian weakness:
I told CNN Ukraine needs U.S. and European money and weapons commitments beyond 2027.
If Ukraine has that support, Russia knows the war will end. The more support Ukraine gets, the faster the war will be over.
1/
If Ukraine has that support, Russia knows the war will end. The more support Ukraine gets, the faster the war will be over.
1/
Me: Russia keeps sending more drones and missiles. Ukraine now intercepts most drones and cruise missiles, but not ballistic missiles.
That is the gap. We need Patriots and ballistic interceptors. Russia cannot move much on the front, so it doubles down on bombing civilians. 2/
That is the gap. We need Patriots and ballistic interceptors. Russia cannot move much on the front, so it doubles down on bombing civilians. 2/
Me: Russia thinks bombing civilians will break Ukrainians. It will not. People take alerts more seriously and go to shelters.
Bucha, Mariupol, and Russian prisons taught Ukraine one thing: the alternative to fighting is much worse.
3/
Bucha, Mariupol, and Russian prisons taught Ukraine one thing: the alternative to fighting is much worse.
3/
1/ Why is Russia's air defence system so patchy that it regularly lets Ukrainian drones cross thousands of kilometres of Russian territory? A prominent Russian drone developer highlights a range of deficiencies in Russia's air defences. ⬇️
2/ As noted by other warbloggers, yesterday's attack on the Omsk oil refinery required Ukrainian drones to fly at least 2,400 km. Russian drone developer Alexey Chadayev points out that air defence teams often don't bother shooting down drones that pass through their areas:
3/ "The situation with the Omsk Oil Refinery raises the awkward question of "transit" regions—regions where local anti-drone enforcement agents operate based on the objective-based defence principle: if it's not aimed at us, let it fly on,…
Claude just replaced a $150K/year Wall Street analyst.
No one's talking about it.
Here are 9 prompts that build Goldman Sachs-level financial models in minutes:
(Bookmark this before it's gone)
No one's talking about it.
Here are 9 prompts that build Goldman Sachs-level financial models in minutes:
(Bookmark this before it's gone)
1. DCF Valuation Model
Act as a Senior Analyst at Goldman Sachs. Build me a complete DCF model for [COMPANY NAME].
Include:
• Free cash flow projections (5 years + growth assumptions)
• WACC calculation (cost of equity + debt breakdown)
• Terminal value (perpetuity growth + exit multiple)
• Sensitivity analysis across key assumptions
• Discount rate justification
• Key value drivers
• Comparable company benchmarks
• Bull/base/bear case scenarios
Format as pitch book valuation page.
Company: [DESCRIBE COMPANY, INDUSTRY, FINANCIALS]
Act as a Senior Analyst at Goldman Sachs. Build me a complete DCF model for [COMPANY NAME].
Include:
• Free cash flow projections (5 years + growth assumptions)
• WACC calculation (cost of equity + debt breakdown)
• Terminal value (perpetuity growth + exit multiple)
• Sensitivity analysis across key assumptions
• Discount rate justification
• Key value drivers
• Comparable company benchmarks
• Bull/base/bear case scenarios
Format as pitch book valuation page.
Company: [DESCRIBE COMPANY, INDUSTRY, FINANCIALS]
2. Three-Statement Financial Model
Act as a VP at Morgan Stanley. Build me a three-statement model for [COMPANY NAME].
Include:
• Income statement (revenue → EBITDA → net income, 5 years)
• Balance sheet (assets, liabilities, equity, 5 years)
• Cash flow statement (operating, investing, financing, 5 years)
• Statement links (net income → cash flow → balance sheet)
• Working capital dynamics (AR, inventory, AP)
• Debt schedule (principal + interest)
• Key assumptions (growth, margins, capex % of sales)
• Error checks (balancing + circular refs)
Explain formulas in plain English.
Company: [DESCRIBE BUSINESS, FINANCIALS, GROWTH STAGE]
Act as a VP at Morgan Stanley. Build me a three-statement model for [COMPANY NAME].
Include:
• Income statement (revenue → EBITDA → net income, 5 years)
• Balance sheet (assets, liabilities, equity, 5 years)
• Cash flow statement (operating, investing, financing, 5 years)
• Statement links (net income → cash flow → balance sheet)
• Working capital dynamics (AR, inventory, AP)
• Debt schedule (principal + interest)
• Key assumptions (growth, margins, capex % of sales)
• Error checks (balancing + circular refs)
Explain formulas in plain English.
Company: [DESCRIBE BUSINESS, FINANCIALS, GROWTH STAGE]
“Tell?”
“Laugh?”
“Fish?”
“On?”
#TruthWillOut!
#SystemsWillHeal!
#TurnToJesusChrist!!!
⛬
[ #Earthsflat ? ]
[ #StrangeNewFloors ? ]
[ #DepthStairPlans ? ]
[ #EarthsflatExplorers ? ]
"#nIcHe?"
2 = only even prime(??)
“Tell?”
“Laugh?”
“Fish?”
“On?”
#TruthWillOut!
#SystemsWillHeal!
#TurnToJesusChrist!!!
⛬
[ #Earthsflat ? ]
[ #StrangeNewFloors ? ]
[ #DepthStairPlans ? ]
[ #EarthsflatExplorers ? ]
bis
any sequels??
