The problem with most supplements is the deuterium they deliver.
Stephanie Seneff, MIT researcher:
"People are loading up on supplements that are actually hurting them — they're not supplying the low deuterium resource that would have happened if it had been biological."
Most supplements are made in chemistry labs.
The molecules are chemically identical to their natural counterparts.
But they lack one critical property: deuterium depletion.
Deuterium is a heavy form of hydrogen that damages ATPase pumps in the mitochondria.
Melatonin is the clearest example.
Your gut produces 400x more melatonin than your pineal gland — most of it inside mitochondria.
Seneff: Melatonin is not primarily a sleep hormone. It is a deuterium depletion system.
Here's the mechanism:
Gut microbes produce hydrogen gas that is 80% deuterium depleted.
That gas feeds a chain of conversions — producing methyl and acetyl groups that are severely low in deuterium.
Those methyl and acetyl groups get attached to serotonin, converting it into melatonin.
Each melatonin molecule now carries depleted hydrogen — ready to be delivered to the mitochondria.
Inside gut cells (enterocytes), an enzyme called CYP2C19 strips the methyl group off melatonin.
Each time it does, it releases four molecules of deuterium-depleted water directly into the mitochondria — protecting the ATPase pumps that generate your cellular energy.
Four depleted water molecules. Per cycle. To the ATPase pumps that need them most.
When melatonin is made synthetically — which is virtually all commercial melatonin — the methyl and acetyl groups come from bulk chemicals made in a lab.
Random high deuterium content. The biological depletion step never happened.
Your body cannot tell the difference.
Sleep improves. Antioxidant effects occur.
But the deuterium depletion cycle doesn't run. The mitochondria don't get what they actually need.
The short-term benefit masks the long-term harm.
The TMAO (Trimethylamine N-oxide) evidence:
TMAO is a marker for deuterium toxicity — deuterium-loaded methyl groups accumulating systemically.
People who ate eggs — no TMAO increase.
People who took synthetic choline supplements — elevated TMAO.
The mechanism: enzymes that metabolize methyl groups can detect deuterium — and refuse to process it.
The trimethylamine survives in the gut. Gets oxidized in the liver. Becomes TMAO in the blood.
The same problem applies to:
N-acetylcysteine (NAC) — the acetyl group is low deuterium from gut microbes, unpredictable when synthetic.
Choline bitartrate — Seneff: "If you're taking choline bitartrate, you need to stop."
Methionine — methionine-deficient rats lived longer in one study.
Seneff's interpretation: methionine restriction extended lifespan not because methionine itself is harmful — but because the rats stopped receiving deuterium-loaded synthetic methionine.
Their gut microbes produced it naturally — low deuterium.
The rats getting synthetic methionine wrecked their mitochondria with deuterium-enriched methyl groups.
The deficient rats didn't.
Methylated B vitamins — likely synthetic, likely the same problem.
The studies testing these supplements never account for the fact that they're synthetic.
They have no idea that's even a variable worth measuring.
What to do instead:
- Get methionine from meat, fish and eggs — not synthetic amino acid supplements.
- Get choline from eggs and animal foods — not choline bitartrate.
- Get tryptophan from food — chicken, turkey, beef, pork, fish, eggs, hard cheeses (parmesan, cheddar). Your gut microbes convert it through the biological pathway naturally, producing depleted melatonin the way biology intended.
One study: tryptophan loading increases serum melatonin 4-fold — even in rats without a pineal gland, confirming the melatonin was gut-sourced not pineal-sourced.
- Animal fats — butter, tallow — are among the lowest deuterium foods available. Derived from acetate produced by gut microbes from deuterium-depleted hydrogen gas. The same pathway that makes biological methyl groups low in deuterium.
- Eat certified organic. Glyphosate disrupts the gut microbiome — which disrupts the entire deuterium management system upstream.
- Fermented foods support acetate production and the whole chain. Whenever the food is fermented, the microbes are making nutrients that are low in deuterium.
- Keep your gut microbiome healthy. It is your primary deuterium management system.
Seneff is 78 years old. Still writing papers. Mentally sharp. Doesn't take any supplements.
"I don't take any supplements. None of these organic molecules. None."
The supplement industry sells you the molecule.
They don't sell you the mechanism biology built into the production process.
P.S. Want to understand how food choices affect your deuterium load & mitochondrial energy production?
Day 4 of my free 5-day email course covers why what you eat — and where it comes from — matters more than most people realize.
Full mechanism detailed in: Seneff, Nigh & Kyriakopoulos: Regulation of Melatonin Metabolism by Gut Microbes and the Role of Deuterium (preprint, 2025)
1/ Just built a Ruby CLI tool with Claude. Fetches ~93 Wikipedia pages, splits them into sections, classifies each via LLM, scores and ranks them, builds a cool, useful table. ~1500 lines of code. Seven sessions. I wrote virtually none of it myself. 🧵
2/ It's for WikiProject Intellectual Diversity—monitors policy talk pages and noticeboards for discussions relevant to the project's goals. Hundreds of active threads at any time, most irrelevant. The scanner finds the ones that aren't.
3/ My role: project owner/manager. Claude's role: programmer. Yup—that's it.
I made design decisions: what to build, how to score things, what to ask the LLM, which pages to monitor. Claude translated those into working Ruby. Almost everything worked first try.
BPC-157 REVERSED Parkinson’s paralysis in mice. In 24 hours.
You think Parkinson’s is an old person’s disease. You’re wrong.
It starts in the gut decades before the tremor. By the time your hands shake, the neurons are gone.
Every day it’s already:
→ Killing the neurons that control movement
→ Breaking the gut lining feeding your brain
→ Building the disease coming for you
You didn’t escape it. You just haven’t felt it yet.
They poisoned lab mice with MPTP — the exact toxin that causes Parkinson’s damage. One group got BPC-157. Paralysis reversed. Tremor gone. Movement back.
The other group? Frozen. Rigid. Permanent.
60% of Parkinson’s patients had severe constipation for decades before the first tremor. Loss of smell. Acting out dreams. Anxiety from nowhere.
If any of this sounds familiar — it’s already started.
This isn’t a brain disease.
It’s a gut disease we’ve been treating in the wrong organ.
Stop drugging the future tremor.
Heal the gut now.
Getting 50+ DMs a day asking which brand I use.
It’s @barrierhealth. Only oral BPC that survives stomach acid — enteric-coated tablets, third-party tested, pharmaceutical-grade. I tried 3 before this one.
BPC-157 didn’t just reverse Parkinson’s paralysis — it also:
— reversed NSAID brain inflammation
— restored memory after stroke
— modulated dopamine and serotonin
— protected neurons from dying
— healed leaky gut in 3 days
— reversed painkiller brain damage
— counteracted anxiety in animal models
— improved cognition after brain injury
— rebuilt the gut-brain highway
— rebuilt gut lining leaking toxins to your brain
🧵 THREAD: You've heard the phrase "OUR DEMOCRACY" a million times. But what exactly is "OUR DEMOCRACY"? 🤔
When they say "democracy," they don't mean a republic. They don't mean consent of the governed. They don't mean your right to choose your own leaders.
They mean a system where "institutions" - NGOs, multilaterals, the permanent bureaucracy - advance a set of values they consider settled: equality, social justice, cosmopolitanism, global governance. These values aren't proposals to be voted on. They're treated as moral prerequisites that must be true *before* your vote counts.
Despite what they say, they aren't for checks and balances. Checks and balances limit what government can do to you. This limits what you can do to *them*. The brakes are on accountability, not power. The institutions that set the boundaries of acceptable policy have put themselves beyond the reach of the electorate, and they call that arrangement "democracy."
Trump has been an existential threat to this system since the moment he said "drain the swamp" ... because the swamp IS the system. When he threatened those institutions, he didn't threaten the republic. He threatened their immunity from it.
And they said so. On camera. At their own events. In their own words.
As always, patience as I pull together the thread.👇
Robert Kagan:
"I would say there is an argument for saying give me some smoke filled rooms... they weeded out the Donald Trumps of this world."
Backroom deals instead of primaries. Because primaries are how you got Trump... and the old gatekeepers would have stopped him.
Think Kagan's an outlier? Here's Brookings senior fellow William Galston at the National Endowment for Democracy's (NED) most prestigious annual lecture.
He explains that "liberal democracy" requires "some abridgement of majoritarianism."
Translation: democracy means limiting what the majority can do.
Evan Solomon @EvanLSolomon continues to engage in utterly contemptible behaviour that reveals his profound disregard for ethical standards in public office, and his undeniable ongoing attachment to Eurasia Group. @EurasiaGroup The fact that his voicemail remains fully active, and that callers can still reach him directly through old extensions while he holds the position of member of parliament and minister, demonstrates his complete failure to separate from the firm, and it proves beyond any reasonable doubt that he is effectively still working there in a way that violates every expectation of transparency, and accountability. This persistent issue shows his negligent attitude toward cleaning up his affairs properly, and it creates an unmistakable appearance of conflict that benefits his elite networks at the expense of ordinary Canadians who fund government operations through their taxes.
Such irresponsible conduct while overseeing substantial spending on artificial intelligence initiatives and digital innovation projects highlights Solomon's arrogant sense of entitlement, and his willingness to maintain hidden connections that should have ended long ago. The repeated evidence from calls connecting straight to him confirms that he has not truly departed from Eurasia Group despite any public claims otherwise, and this kind of sloppy management reflects his poor judgment, and his prioritization of personal influence over proper accountability while the firm continues to siphon millions of dollars in Canadian taxpayer money through government contracts including a total of over $1.5 million with specific awards like $446,210.91 from Natural Resources Canada for geopolitical research, analysis, and insights. He bears full responsibility for allowing these channels to stay open, and it fuels legitimate outrage among those who expect ministers to operate without any lingering private ties especially given the history of contracts with the organization, and the direct involvement of the Carney family orbit.
This entire situation involving active voicemails, live answers from him as a sitting minister, and the ongoing flow of public funds into Eurasia Group demands urgent scrutiny because it suggests deep corruption through informal or unpaid work that undermines conflict of interest rules, and it erodes public confidence in the entire process of governance. Solomon has failed repeatedly to address this problem properly, and his behaviour looks exactly like someone who never left Eurasia Group at all which only adds to the suspicions surrounding the taxpayer money they are taking while he directs policy that could further enrich these interconnected circles. He should face immediate consequences for this pattern of deception, negligence, and outright corruption that harms the integrity of his office, and wastes the trust placed in him by voters.
To report Evan Solomon for potential conflict of interest or ethics violations:
File a formal complaint directly with the Office of the Conflict of Interest and Ethics Commissioner.
Send a detailed written submission (include your call logs, screenshots of voicemail/extension, contract details from open.canada.ca, and timeline) to:
info@cie.parl.gc.ca or by mail to:
Conflict of Interest and Ethics Commissioner, Parliament of Canada, Ottawa, ON K1A 0A6.
You can also contact the Commissioner’s office by phone at 613-995-7022 for guidance on filing.
Additional routes:
- Raise it with opposition MPs (e.g., Conservative or NDP offices) to trigger parliamentary questions.
- Submit to the House of Commons Standing Committee on Access to Information, Privacy and Ethics.
- File Access to Information requests for more disclosure records.
For those of you in the back, let me explain the ruling to those who have not read Virginia's constitution and laws.
The Tazewell County Circuit Court’s Final Judgment (entered April 22, 2026, in Civil Action No. CL26-266) is structured as a series of bullet-point declarations. Judge Jack Hurley granted the plaintiffs (Republican National Committee et al.) full relief on their Verified Complaint challenging House Joint Resolution 6007 (HJR 6007)—the Democrat-backed proposal for a constitutional amendment on congressional redistricting. The court ruled the entire process invalid from the beginning (“void ab initio”), voiding the April 21, 2026 referendum and all 2.5 million votes cast on it. Below is each bullet point from the decision, with a plain-English explanation and direct citations to the Virginia Constitution and Code it references.
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• GRANTS final judgment in Plaintiffs’ favor on all counts of their Verified Complaint
This is the overarching ruling: the court agreed with every legal claim in the plaintiffs’ lawsuit. The Verified Complaint alleged that the General Assembly’s handling of HJR 6007 violated multiple procedural rules, constitutional requirements for amending the Constitution, and requirements for submitting questions to voters. By granting judgment on “all counts,” the court declared the entire amendment process legally dead.
2/7
• DECLARES that HJR 6007 is void ab initio because it violated House Joint Resolution 428 and House Joint Resolution 6001, and any action taken thereon is an invalid expansion of the General Assembly’s call to the Governor for the 2024 Special Session
HJR 6007 was the joint resolution that actually proposed the redistricting amendment. House Joint Resolution 428 (2024) formally asked the Governor to call the 2024 Special Session I and set its schedule. House Joint Resolution 6001 explicitly limited the legislation that could be considered in that special session. The court ruled that HJR 6007 went far beyond what those two authorizing resolutions permitted. Because the special session’s “call” (the legal boundaries set by the General Assembly itself) was exceeded, the amendment proposal was invalid from the moment it was introduced.
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You've probably already wondered what the fuck these little balls under the head of your dick are, after all, is it a venereal disease, something normal, a little dick choquito? You can chill, it's not an STI (especially since you don't even fuck), sit your ass down that I'll explain
What you've got at the tip of the mast of the Flying Dutchman are called Tyson's glands, or penile sebaceous glands, a fancy name for something whose function is to serve as the natural "spit" for the nheco nheco at the bar.
These glands produce a lubricating liquid called smegma (sounds a hell of a lot like the name of a parasitic disease ffs), whose function is to lubricate the bingola for the act of carnal conjunction, commonly known as fucking.
Not by banning it. By requiring identity verification for anyone who contributes code.
No more anonymous developers. No more pseudonymous contributors. No more building tools without attaching your real name and government ID to every line of code you write.
If they can identify every developer, they can control what gets built. And if they can control what gets built, they can stop anything that threatens their power.
2/ Code is speech.
The Supreme Court has affirmed this. Writing software is protected by the First Amendment just like writing a book or publishing an article.
But if you cannot write code anonymously, you cannot speak freely.
Identity verification does not just eliminate anonymous development. It eliminates free speech for anyone building tools that challenge power.
3/ You want to build encryption software that protects privacy.
You write the code. You test it. It works. You publish it as open source so anyone can use it.
But now the repository requires verified identity. You must link your real name to the project. Your government ID. Your location.
You know what happens next. The people who do not want strong encryption to exist will know exactly who built it. And they will come for you.
I was 29kg overweight, had a huge belly, and I wanted to reach 13% body fat in 2026. I did it with these 25 rules:
Rule 1. STOP RUNNING.
Rule 2. Eat protein first to avoid overeating - you burn calories just digesting it.
Rule 3. Lift 3X per week: Push, Pull, Legs, and core after.
Rule 4. Diet goal: 1500 Deficit of 1000 calories = 1 kilo per week.
Rule 5. Take photos and measure weight same time every morning.
How to deeply satisfy a woman in bed (without guessing)
Most men rely on luck.
That’s why they stay average.
Pleasure is a skill.
And these 8 techniques will make you unforgettable:🧵
1. Warm Her Up Properly With F0replay
The biggest difference between male and female arousal is speed. A man can go from zero to ready almost instantly. A woman cannot. Her body takes time because her arousal system is built on gradual escalation. Blood flow must increase to her sensitive areas, her muscles need time to relax, her breathing needs to deepen, and her mind needs time to shift into a fully intimate state.
When you rush, she cannot enjoy anything. When you take your time, her body becomes ten times more sensitive, responsive, and hungry for your touch.
Start with deep kissing. Start slow. Keep your lips soft at first, then deepen the kiss as her breathing changes. Move from her lips to her neck, her ears, her jawline, and her collarbone. Each kiss should feel soft and sensual. The more you kiss her, the wetter she becomes.
Use teasing touches. Her body has a lot of nerve endings that activate before you even touch the main areas. Slide your hands along her hips, inner thighs, stomach, ribcage, shoulders, and lower back. Touch lightly first, then gradually firmer as her body relaxes. Avoid the most sensitive areas at the beginning because anticipation is what multiplies her pleasure. The longer you delay touching the places she wants, the stronger her arousal climbs.
Add verbal f0replay. Women respond emotionally to tone, confidence, and intention. Tell her how good she feels. Tell her how much you want her. Whisper what you plan to do to her. Speak slowly and deeply. The mind is the doorway to her body, and your voice is one of the strongest tools you have.
The man who masters f0replay becomes unforgettable because he activates her entire body and her entire mind.
2. Stimulate Her Mind First
For most women, arousal begins in the mind before it ever reaches the body.
If her thoughts are distracted, anxious, or disconnected, her body will struggle to respond fully. This is why mental stimulation is not optional. It is essential.
The most satisfying lovers understand that desire grows when a woman feels emotionally engaged, guided, and wanted.
Here is how to stimulate her mind effectively:
Leading the Moment
Women are deeply attracted to men who can lead with calm confidence. Leadership creates safety, and safety allows her to relax into pleasure.
Tell her where you want her to be. Gently guide her movements. Let her feel that you know what you are doing and where things are going.
This removes mental pressure from her and allows her to fully surrender to the experience.
Strong Eye Contact
Eye contact creates intensity, trust, and emotional connection. Holding her gaze during intimate moments makes her feel seen, chosen, and desired.
Even brief moments of deep eye contact can significantly heighten arousal and emotional closeness.
Play With Uncertainty
Do not rush to give her everything at once. Slow down when she expects more. Pause when she anticipates the next move.
This controlled unpredictability keeps her mind engaged and emotionally invested. It creates tension, excitement, and curiosity.
When her mind is fully stimulated, her body follows naturally and powerfully.
Il “predominio energetico” USA rischia di naufragare nel Golfo Persico
Il mio nuovo articolo su #IntelligenceForThePeople
🧵
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(Link all’articolo in fondo al thread)
Il concetto di “predominio energetico” è uno dei cardini della politica estera ed economica della Casa Bianca.
Esso si riferisce non soltanto alla capacità produttiva e di esportazione, ma alla possibilità di controllare infrastrutture, giacimenti, flussi energetici mondiali.
2/
Non siamo dunque di fronte a una mera politica energetica, ma a una vera e propria strategia geopolitica, come ha scritto Diana Furchtgott-Roth, una delle “menti” dell’amministrazione che hanno elaborato questa dottrina. 3/ heritage.org/energy/comment…
1/ Growing discontent about Russian government policies is reflected in an increasing willingness by Russian commentators to directly attack Vladimir Putin – still a very risky move. Warblogger Egor Guzenko calls Putin a liar over Internet shutdowns. ⬇️
2/ Writing on his channel 'Thirteenth', Guzenko – a veteran Russian nationalist who has been fighting in Ukraine from 2014 onwards – ignores the ever-present threat of the FSB and gives Putin both barrels:
3/ "You'll have to forgive me, but you know, Comrade Supreme Commander-in-Chief, what you're saying now is a blatant lie."