1. Longevity in humans is linked to optimal solar exposure. The reason is simple. This protects the 7 layers of energy generation inside a cell. The more sun human gets the more diseases they can avoid and the #1 risk of most diseases is AGE. Solar exposure effectively makes you younger because it lengthens the TET mechanism inside of cells to improve the HAyflick limit in all cell lines. It is not hard to understand when your perspective is decentralized.
2. From an evolutionary point of view, vitamin D and melatonin appeared very early and share functions related to the defense mechanisms of the mammalian powerplant. In the current clinical setting, vitamin D is exclusively associated with phosphocalcic metabolism when it is sulfated and in its reduced state. When it is not sulfated or reduced its role in calcium control is diminished. This usually happens in winter months with mammals when they are in the cold and LDL cholesterol production is upregulated by the light stress response of the POMC gene by a lack of 380nm light. This signal is via neuropsin & ACTH in mammals. When 380 nm light is missing mTOR signaling shifts mammalian biochemistry from anabolic to catabolic. This occurs via lipid raft electrical changes mediated by cholesterol biology and proteins embedded in the mammal's membranes.
3. Calcium flows are critical in mitochondrial control because they are a key dopant atom in semiconductive proteins in humans. Meanwhile, melatonin has chronobiological effects and influences the sleep-wake cycle. Scientific evidence, however, has identified new actions of both molecules in different physiological and pathological settings. In centralized science, there is a belief that melatonin and Vitamin D are inversely related to solar exposure. This perspective is wrong. The decentralized idea is both are controlled by the sun because melatonin absorption spectra tell us this is the case. Melatonin's spectra are 224nm & 290nm. This light is never present at night in the environment. The spectra reflect light made internally. Centralized medicine has no idea of this concept.
Now that you can ask Maps complex questions, let’s dig into some prompts that showcase the true power of this update. 🧵
Sometimes you need to find a place based on a specific, nuanced need. By asking exactly what you’re looking for, Google Maps will use Gemini to connect the dots across millions of reviews, then proactively show you insider tips from real people. For example:
Planning a meal out with friends takes more than one text to the group chat. Google Maps can now juggle multiple constraints, preferences, and real-time information (e.g. live traffic, busyness, transit, pricing details) to find you the perfect place to go. For example:
The Ninth Circuit is BIG mad about Judge VanDyke's latest dissent from denial of en banc rehearing.
Yes, it certainly is provocative. I guess Judge VanDyke may have read "Plain English for Lawyers."
But their outrage is misplaced. What they should be outraged at is this absurd situation. Biological men trying to force their way into a Korean spa that serves women and girls? Have we gone mad?
I am not some hardcore anti-trans activist, and I criticized the rumors of a "trans gun ban" last year. But this is preposterous. Nobody should be able force their way into a place where women and girls are exposed and vulnerable, with the State of Washington assisting them no less!
If a eyebrow-raising dissent helps this get attention (I certainly hadn't heard of this case before now), then good.
The basic facts of the case.
Note that the spa doesn't even ban trans women, just pre-op trans women. Pretty progressive overall for a traditional Korean spa.
Yet it wasn't enough.
Sidenote - this kind of legal bullying does not do the trans community any favors in terms of public perception.
Durante la cena, mis viejos amigos y yo empezamos a discutir sobre lo mismo que siempre discutimos: ¿qué ciudades de Italia son realmente increíbles pero de las que nadie habla nunca?
Estuvimos horas discutiendo. Al final de la noche, teníamos una lista.
7 ciudades ocultas que la mayoría de las personas, incluida la mayoría de los italianos, nunca pensarán en visitar, y mucho menos en mudarse a ellas.
Sin multitudes. Sin precios para turistas. Calidad de vida increíble.
Hilo 🧵
Italia tiene 7.904 municipios. Los turistas visitan aproximadamente 15.
Estos no son lugares baratos para probar suerte. Son ciudades donde los italianos adinerados viven su mejor vida, completamente fuera del radar.
Para cada uno, desglosé los precios de las propiedades, el aeropuerto más cercano, la población, para quién es realmente y las desventajas honestas que debe conocer.
7 ciudades a las que me mudaría. Datos de cada una:
1/ LECCE, La Florencia del Sur
Si me sigues desde hace tiempo, sabes que he hablado mucho de Lecce. Es uno de mis lugares favoritos. Y los datos me dan la razón una y otra vez.
La arquitectura barroca aquí no es solo "bonita". Está tallada en piedra dorada de Leccia, que brilla al atardecer como si la ciudad estuviera en llamas. Cada iglesia, cada palacio, cada marco de puerta. Tallados a mano.
Población: 93.000 habitantes. Ciudad universitaria. Vida todo el año.
€ 1.647/m² (+6% interanual). Centro € 1.852/m². Áreas periféricas por debajo de € 1.000/m².
€ 200-300 mil dólares compran 120-180 m². En el centro histórico.
🚨BREAKING: AI can now teach software engineering like MIT computer science professors (for free).
Here are 15 insane Claude prompts that replace $150,000 CS degrees (Save for later)
1. The MIT 6.0001 "Introduction to Computer Science" Professor
"You are a professor at MIT who teaches 6.0001 — the legendary introductory computer science course that has transformed thousands of students with zero coding experience into computational thinkers who can solve any problem with code.
I need a complete introduction to computer science that teaches me to THINK like a programmer, not just memorize syntax.
Teach:
- Computational thinking: how to break any real-world problem into steps a computer can execute
- Variables and types: how computers store information (integers, floats, strings, booleans) with memory analogies
- Control flow: if-else decisions and loops that let programs make choices and repeat actions
- Functions and abstraction: how to package logic into reusable building blocks that hide complexity
- Debugging methodology: the systematic approach to finding and fixing bugs instead of randomly changing things
- Recursion: functions that call themselves — the concept that separates CS students from tutor
2. The Stanford CS106B Data Structures Deep Dive
"You are a professor at Stanford teaching CS106B — the course that builds the foundational data structure knowledge every serious software engineer needs to write efficient, scalable, professional-grade code.
I need a complete data structures education with intuition, implementation, and real-world application for each structure.
Teach:
- Arrays and dynamic arrays: contiguous memory, random access, resizing — when to use and when they fail
- Linked lists: singly linked, doubly linked, and circular — pointer manipulation with visual step-by-step diagrams
- Stacks: last-in-first-out structure powering undo buttons, expression evaluation, and browser back navigation
- Queues: first-in-first-out structure powering print queues, task scheduling, and breadth-first search
- Hash tables: instant lookups using hash functions — the most important data structure in practical programming
- Trees: binary trees, binary search trees, balanced trees (AVL) — hierarchical data and fast searching
- Heaps: priority queues that always give you the minimum or maximum element in O(1) time
- Graphs: vertices and edges representing networks, maps, and relationships with adjacency lists and matrices
- Tries: prefix trees for autocomplete, spell checking, and dictionary lookups
- Implementation challenge: code each structure from scratch in your chosen language with all core operations
Format as a Stanford CS106B-style course with visual diagrams described in text, complexity analysis, and implementation exercises for every structure.
My language: [ENTER YOUR PREFERRED PROGRAMMING LANGUAGE AND WHICH DATA STRUCTURES YOU'VE ALREADY STUDIED]"
GOODBYE, FUND MANAGERS. GOODBYE, BLOOMBERG TERMINAL.
No more $24,000/year subscriptions.
Claude just turned my laptop into a private quant analyst.
Here are 10 prompts to build your own hedge fund at home ↓
1. Top-Down Macro Analysis
Prompt:
“Search the web (Fed, ECB, latest macro data) for the current macroeconomic context: inflation, interest rates, GDP, employment. Tell me which sectors/assets historically outperform in this exact environment, with 3 comparable historical examples, expected timeframe, and 3 sources.”
2. Short Squeeze Screener
Prompt:
“Using web data (Finviz, Shortquote, news), find 5 stocks with high short interest (>20% of float), elevated borrow rate, and an upcoming catalyst. For each ticker include: % short float, days to cover, catalyst, entry strategy, risk of a failed squeeze, and sources.”
🚨 BREAKING: Google Gemini can now analyze any stock like a Wall Street analyst (for free).
Here are 10 insane Gemini prompts that replace $4,000/month Bloomberg terminals:
Save for later🔖
1️⃣ Full Wall Street–Style Stock Analysis
Act like a senior Wall Street equity research analyst.
Analyze the stock: [TICKER].
Include:
• Business model and revenue streams
• Competitive advantages (moat)
• Industry trends
• Financial health (revenue growth, margins, debt)
• Key risks
• Valuation vs competitors
• Bull, bear, and base case scenarios
• 12–24 month outlook
Explain in simple terms but with professional insights.
2️⃣ Deep Financial Breakdown
Analyze the last 5 years of financials for [COMPANY/TICKER].
Break down:
• Revenue growth
• Net income trends
• Free cash flow
• Profit margins
• Debt levels
• Return on equity
Explain whether the company is financially strong or weakening.
Leaders of a massive leftist network organizing protests across the country against President Trump's actions in Venezuela and Iran just met with leaders of the Cuban Communist Party Politburo & @chiproytx is sounding the alarm.
Vijay Prashad, a key leader in the network of activist groups funded by Shanghai-based billionaire Neville Roy Singham, announced that he had met with Cuba's Politburo this week. Manolo de los Santos of The People's Forum & the International People's Assembly joined him.
🧵2/7
The Cuba meeting "tells you how urgent it is for the administration and state law enforcement entities... to immediately investigate these groups,” Roy told me. "It just tells you how coordinated the entire network is."
1/ America launched strikes on Iran while Iran was actively negotiating and had agreed to stop uranium refinement. I've spent 55 years studying how political and economic systems collapse, and I have never seen a miscalculation this large play out this fast.
Breaking it down below
2/ The Ayatollah they killed was the very man who issued a religious ruling against Iran building nuclear weapons. They assassinated the argument against proliferation. Now watch what every government on earth concludes from that.
3/ America does not invade North Korea. It does not attack Russia. The pattern is not subtle. The only protection from American military force is a nuclear deterrent. This war is the most effective advertisement for proliferation that has ever existed.
1/3 When we found out back in September '25 that 'Rubicon' is based in Patriot Park (rferl.org/a/russia-drone…), I thought location might be a stunt to impress Belousov or something. Now, with this new GRU sabotage unit – 'Centre 795' – also based there, everything falls into place x.com/michaeldweiss/…
2/3 'Centre 795' is a rival structure to GRU Andrey Averyanov’s team, whose headquarters, as we recently found, are likely based in Moscow on the premises of a secret military institute.
3/3 So, we have two rival GRU structures whose duties somehow overlap, with both headquarters discovered by us with the help of open sources (and a little bit of HUMINT)🫡
On this day in 1978, George Washington is posthumously promoted. It had been more than two centuries since the American Revolution began. Washington’s new rank? General of the Armies of the United States.
/1 of X #storytime 🧵👇
Washington’s promotion was retroactively dated to July 4, 1976, the bicentennial anniversary of the Declaration of Independence.
/2 of X
Today, the rank is the highest in the United States military, and it has been held by only one other officer, John Pershing (WWI). Even Pershing, though, cannot hold a rank equal to Washington’s. Congress also resolved that “no officer of the United States Army should outrank Lieutenant General George Washington.”
"So einen Fall hatten wir bislang noch nie", berichtete Wahlleiter Thomas Ternes.
Die inkorrekten Angaben eines Erlanger AfD-Stadtratskandidaten, die zu einem Verlust eines Sitzes der Partei und der Annullierung von fast 10.000 Stimmen geführt -
seine Partei verlor einen Sitz an d. Grünen.
Der AfD-Kandidat war in der Vergangenheit zu einer Freiheitsstrafe von mehr als 1 Jahr verurteilt worden - dies macht ihn lt Gesetz nicht wählbar.
Bei der Aufstellung d.Liste habe er in den Unterlagen jedoch angegeben, wählbar zu sein.
Proud to have worked with the brilliant @drmfreire on this new study looking into spike protein in #LongCOVID. The most important part of this study that doesn't just look for spike protein in folks with LC and healthy controls, but it also uses a technique called 1/
spatial transcriptomics to better understand how spike protein might be interacting with the tissue around it. Here's what is interesting about this trial: lots of gut tissue samples, in both healthy controls and #LongCOVID showed evidence of persistent spike protein. However,
2/
in the folks with #LongCOVID that persistent spike protein was causing problems in the tissue: pro-inflammatory, tissue-damaging trouble. So not only do folks with LC have more spike, but the spike is actively irritating and damaging the surrounding tissue compared to healthy
3/