Recent well liked threads
JUSTICIA y PENSAMIENTO CRÍTICO
En el año 156 a.e.c. el escéptico Carneades acudió desde Atenas a la ciudad eterna y demostró 2 cosas:
1) El 1er día demostró que la justicia era el 1er bien
2) El 2º día demostró que lo dicho el 1er día era falso
¿Cómo lo hizo?
🧵Abro hilo
En el año 156 a.e.c. el escéptico Carneades acudió desde Atenas a la ciudad eterna y demostró 2 cosas:
1) El 1er día demostró que la justicia era el 1er bien
2) El 2º día demostró que lo dicho el 1er día era falso
¿Cómo lo hizo?
🧵Abro hilo
Según Carneadas, educado en la escuela escéptica y firme cuestionador de todo tipo de dogmatismos, la JUSTICIA es una idea problemática y compleja que solo es útil para el gobierno de las sociedades pero no necesariamente es VERDAD o BIEN en sí misma.
Los jóvenes romanos quedaron completamente sorprendidos ante tal argumento.
Acostumbrados a una educación jurisprudente y basada en el derecho romano, veían como JUSTICIA y PRUDENCIA son al mismo tiempo la mayor parte del tiempo incompatibles.
Carnéades fue aclamado.
Acostumbrados a una educación jurisprudente y basada en el derecho romano, veían como JUSTICIA y PRUDENCIA son al mismo tiempo la mayor parte del tiempo incompatibles.
Carnéades fue aclamado.
The Gut-Brain Axis in Play: When Psychiatrists Treat Constipation 💩🚀 🧵1/
How I use Constipation as a Clinical Diagnostic and Management Marker ✅👇
One of the most fascinating aspects of treating depression is the intricate link between mood and the bowels.
Constipation is a very common symptom in severe melancholic and psychotic depression! ( >association with psychotic depression)
So, two things happen
1. Constipation
2. ‘Worry about constipation’ - this phenomenologically is not anxiety but is often misdiagnosed as such.
Note I am not referring to cases where addressing constipation improves mental state, treats confusion.
I’m talking about cases where long standing treatment of constipation has not shifted the bowels.
Phenomenology 👉As part of phenomenological evaluation -
I ask, "What proportion of your day do you think about this?" the answers are often 70%, 80%, even 90% of the day.
This ‘all consuming’ nature is not just anxious preoccupation BUT rather moving toward overvalued ideation. 🔥
But as clinicians, we must dig deeper-
financial ruminations, obsessional guilt, or pervasive feelings of doom are often present as well. ✅
How do we conceptualise this presentation in clinical practice and can it guide treatment? Absolutely! 1/ 👇
How I use Constipation as a Clinical Diagnostic and Management Marker ✅👇
One of the most fascinating aspects of treating depression is the intricate link between mood and the bowels.
Constipation is a very common symptom in severe melancholic and psychotic depression! ( >association with psychotic depression)
So, two things happen
1. Constipation
2. ‘Worry about constipation’ - this phenomenologically is not anxiety but is often misdiagnosed as such.
Note I am not referring to cases where addressing constipation improves mental state, treats confusion.
I’m talking about cases where long standing treatment of constipation has not shifted the bowels.
Phenomenology 👉As part of phenomenological evaluation -
I ask, "What proportion of your day do you think about this?" the answers are often 70%, 80%, even 90% of the day.
This ‘all consuming’ nature is not just anxious preoccupation BUT rather moving toward overvalued ideation. 🔥
But as clinicians, we must dig deeper-
financial ruminations, obsessional guilt, or pervasive feelings of doom are often present as well. ✅
How do we conceptualise this presentation in clinical practice and can it guide treatment? Absolutely! 1/ 👇
The answer lies in the gut-brain axis, a key player in this clinical scenario.
So what are the links between the Gut and the Brain in this scenario?
1️⃣Dopaminergic Dysfunction:
Did you know that dopamine, plays a crucial role in bowel motility?
In fact, guess which symptom often occurs early in Parkinson’s disease? That’s right-constipation.
Dopamine plays an important role in intestinal homeostasis.
Dopamine receptors, including D1, D3, and D5, are distributed in the intestinal wall- not just in the mucosa but also in the nerve endings of the intestinal wall.
Dopamine D2 receptors, are located specifically in the nerve endings within the intestinal wall. Meanwhile, the D4 receptor is found only in the mucosal layer.
When dopamine deficit states occur as in severe depression ( or many neuroinflammatory states) this can lead to reduced gut motility, resulting in constipation.
Thus , by enhancing dopaminergic activity through specific treatments, we can often see improvements in both the depression construct and bowel function. ✅
2️⃣Noradrenergic pathways :
The autonomic nervous system (ANS), which controls involuntary bodily functions like digestion, also plays a role in this process.
The noradrenergic descending pathway from the brain influences gastrointestinal motility by acting on the lumbosacral spinal defecation center.
In severe depression, ANS dysfunction may contribute to constipation, and addressing this requires a delicate balance- reducing agitation while potentiating NA to promote ANS homeostasis. 2/
So what are the links between the Gut and the Brain in this scenario?
1️⃣Dopaminergic Dysfunction:
Did you know that dopamine, plays a crucial role in bowel motility?
In fact, guess which symptom often occurs early in Parkinson’s disease? That’s right-constipation.
Dopamine plays an important role in intestinal homeostasis.
Dopamine receptors, including D1, D3, and D5, are distributed in the intestinal wall- not just in the mucosa but also in the nerve endings of the intestinal wall.
Dopamine D2 receptors, are located specifically in the nerve endings within the intestinal wall. Meanwhile, the D4 receptor is found only in the mucosal layer.
When dopamine deficit states occur as in severe depression ( or many neuroinflammatory states) this can lead to reduced gut motility, resulting in constipation.
Thus , by enhancing dopaminergic activity through specific treatments, we can often see improvements in both the depression construct and bowel function. ✅
2️⃣Noradrenergic pathways :
The autonomic nervous system (ANS), which controls involuntary bodily functions like digestion, also plays a role in this process.
The noradrenergic descending pathway from the brain influences gastrointestinal motility by acting on the lumbosacral spinal defecation center.
In severe depression, ANS dysfunction may contribute to constipation, and addressing this requires a delicate balance- reducing agitation while potentiating NA to promote ANS homeostasis. 2/
Ok so you might say - well treat the constipation then! And you are right!
BUT
Now what about the ruminations and overvalued ideation about constipation?
Here’s a critical point that’s often overlooked: ruminations and overvalued ideation are frequently unresponsive to antidepressants alone AND rarely in the context of severe depression is there improvement in bowel movements even with multiple laxatives.
This can lead to a common clinical misstep-dismissing these ruminations as mere anxiety or attributing them solely to constipation, which then leads to the prescribing of multiple laxatives without addressing the underlying neurobiological issues. ❌ 3/
BUT
Now what about the ruminations and overvalued ideation about constipation?
Here’s a critical point that’s often overlooked: ruminations and overvalued ideation are frequently unresponsive to antidepressants alone AND rarely in the context of severe depression is there improvement in bowel movements even with multiple laxatives.
This can lead to a common clinical misstep-dismissing these ruminations as mere anxiety or attributing them solely to constipation, which then leads to the prescribing of multiple laxatives without addressing the underlying neurobiological issues. ❌ 3/
Hoy os voy a hablar de la corriente de interiorismo prevalente en nuestra época:
El Neopaquismo
El Neopaquismo
Para entender el Neopaquismo, primero hay que entender un poco lo que es el Paquismo.
El Paquismo es básicamente el diseño de interiores de los pisos Paco del Franquismo y la Transición (aprox. 1965-1985), las casas de los Boomers y early Generación X.
El Paquismo es básicamente el diseño de interiores de los pisos Paco del Franquismo y la Transición (aprox. 1965-1985), las casas de los Boomers y early Generación X.
Se caracteriza por gotelé (para disimular defectos de construcción de las casas baratas), muebles durables de madera maciza, fotos de la familia (comuniones, bautizos, la boda) y displays de vajillas para las visitas.
Really need everyone to stop saying this because it is absolutely not how any of this works.
This isn't the 1950's with one paper master copy in a vault somewhere.
There are dozens if not hundreds of copies of the Epstein Files across multiple departments and agencies. 1/
This isn't the 1950's with one paper master copy in a vault somewhere.
There are dozens if not hundreds of copies of the Epstein Files across multiple departments and agencies. 1/
Not just agencies, but administrations. You think some of the Biden DoJ and FBI who worked the case didn't make backups for this exact scenario?
C'mon. Trump and Bondi don't have control of every digital copy. They can't white out his name without causing discrepancies. 2/
C'mon. Trump and Bondi don't have control of every digital copy. They can't white out his name without causing discrepancies. 2/
No, if they release a doctored copy of the files with Trump stripped out, the real version will hit a NYT reporter's Dropbox within the hour. Trump knows it, Bondi knows it.
What happened yesterday is Trump had his own Goldwater/Rhodes moment like Nicon and Watergate. 3/
What happened yesterday is Trump had his own Goldwater/Rhodes moment like Nicon and Watergate. 3/
Eye problems are one of the most common after-effects of covid infections, and one of the most common issues of Long Covid - but they're not talked about much.
This is part two of my thread working through eye conditions that have become *much more common* since Covid struck.
This is part two of my thread working through eye conditions that have become *much more common* since Covid struck.
Little step up in older adults.
A messy plateau in older working adults.
Gente vou contar uma história aqui que vai deixar muito homem puto, mas é uma lição para mulheres:
Há um ano, um cara que era muito afim de mim me pagou uma viagem pra ilha da Madeira, em Portugal, com tudo incluso, SEM COMPROMISSO. Quartos de hotel separado e tudo 👇🏽
Há um ano, um cara que era muito afim de mim me pagou uma viagem pra ilha da Madeira, em Portugal, com tudo incluso, SEM COMPROMISSO. Quartos de hotel separado e tudo 👇🏽
Eu fui pra ser date dele no casamento do melhor amigo, pq todo mundo era casado e tinha par, menos ele.
Aí ok. Resolvi dar uma chance pra ele.
Eu nunca tinha sido interessada nele pq achava ele meio imaturo, mas ele foi provando que tinha virado adulto, etc.
Aí ok. Resolvi dar uma chance pra ele.
Eu nunca tinha sido interessada nele pq achava ele meio imaturo, mas ele foi provando que tinha virado adulto, etc.
Ele morava em Montreal, onde eu tbm morei por um tempo, e a gente tinha se conhecido lá. E eu morava em Miami na época.
Ele ficou viajando um ano, várias vezes, pra ficar comigo. E assim, apaixonado.
Tipo muito apaixonado.
Ele ficou viajando um ano, várias vezes, pra ficar comigo. E assim, apaixonado.
Tipo muito apaixonado.
BREAKING: Documents reviewed by @BylineTimes show Jeffrey Epstein received real-time internal White House info in 2019 from Trump's inner circle - while working with Steve Bannon to rebuild his public image by filming on Epstein's private island 🧵/1
bylinetimes.com/2025/11/17/jef…
bylinetimes.com/2025/11/17/jef…
On 23 March 2019, Epstein texted Bannon Trump’s private view of his own Vice-President:
“Djt. Now really down on Pence … thinks Pompeo would be better vp … says pence not really loyal.”
This was not public at the time. /2
“Djt. Now really down on Pence … thinks Pompeo would be better vp … says pence not really loyal.”
This was not public at the time. /2
Epstein was relaying live, internal presidential thinking in the kind of detail available only to someone with close access to the Oval Office. And directly to Trump's former chief strategist, Bannon. These details only surfaced publicly months later /3
Voleu saber per què tanta gent votarà Aliança Catalana? No és radicalització: és supervivència.
Fil
Fil
1️⃣ Vaig trobar-me un company de carrera. Feia molts anys que no ens veiem i parlant de tot, em deixa anar:
“Jo a les següents votaré AC. I se me’n fot si em diuen q soc d’ultradreta. Això ja no es pot aguantar més. Cal posar ordre".
Aquesta frase no és anecdòtica. És un símptoma.
“Jo a les següents votaré AC. I se me’n fot si em diuen q soc d’ultradreta. Això ja no es pot aguantar més. Cal posar ordre".
Aquesta frase no és anecdòtica. És un símptoma.
2️⃣ Parlo possiblement d’un perfil concret: classe mitjana treballadora, gent normal, molts formats en escoles privades o concertades, fills de famílies dels 70–90's que van créixer amb l’ideal d’ascens social. Forquilla de 35 a 55 anys
Some observations about documents released by Sen Rand Paul on 30 October 2025 related to Ralph Baric
🧵
🧵
1. It is unsurprising that someone with a CIA-affiliated email address reached out to Baric about a project on coronaviruses in September 2015.
U.S. flu surveillance/testing increased dramatically between 2015-2020, as did P&I cause of death attribution toward "I" influenza and use of code B34.2 · Coronavirus infection, unspecified
x.com/Wood_House76/s…
This doesn't mean Baric was in league with the CIA -- and it's certainly not a smoking gun on the "creation" of virus purported to have caused a pandemic.
It does point to a well-known coronavirus expert being tapped in the service of planned/strategic operations
U.S. flu surveillance/testing increased dramatically between 2015-2020, as did P&I cause of death attribution toward "I" influenza and use of code B34.2 · Coronavirus infection, unspecified
x.com/Wood_House76/s…
This doesn't mean Baric was in league with the CIA -- and it's certainly not a smoking gun on the "creation" of virus purported to have caused a pandemic.
It does point to a well-known coronavirus expert being tapped in the service of planned/strategic operations
2. That Baric would be asked to give a presentation to the ODNI about "the coronavirus" in late January 2020 is also unsurprising and evidence of nothing much.
The committee that classified and named SARS-CoV-2 (of which Baric was a member) had already made its decision about virus species and name and the WHO had endorsed a "blueprint" test.
Baric was very much in the news and fielding inquiries from reporters...as we would expect
The committee that classified and named SARS-CoV-2 (of which Baric was a member) had already made its decision about virus species and name and the WHO had endorsed a "blueprint" test.
Baric was very much in the news and fielding inquiries from reporters...as we would expect
A new type of UAV developed in Iran in 2024 called “Shahed-107” is increasingly being used by Russia.
It has a 4-element CRPA satellite navigation system, a range of several hundred kilometers, and an 8–9 kg warhead.
1/
It has a 4-element CRPA satellite navigation system, a range of several hundred kilometers, and an 8–9 kg warhead.
1/
If produced in quantities in Russia, this gives would yield a mid-range strike UAV with longer range than the Lancet strike UAV, and a bigger warhead than the 2.5 kg warhead than the “Gerbera” UAV.
You @NIHDirector_Jay say Sweden's pandemic strategy succeeded bec of a "metabolically healthy"🤡population
Indeed,a success story...in terms of horrors
"Many elderly people were administered morphine instead of oxygen despite available supplies,effectively ending their lives"
1/7
Indeed,a success story...in terms of horrors
"Many elderly people were administered morphine instead of oxygen despite available supplies,effectively ending their lives"
1/7
PLUS
Researchers omitted data on child mortality🚀spring 2020
"Scandal in Sweden: Paediatrician truncated child death figures to keep schools open" (epidemiologist and paediatrician Jonas Ludvigsson of the Karolinska Institute)
3/7
fr.businessam.be/scandale-en-su…
science.org/content/articl…
Researchers omitted data on child mortality🚀spring 2020
"Scandal in Sweden: Paediatrician truncated child death figures to keep schools open" (epidemiologist and paediatrician Jonas Ludvigsson of the Karolinska Institute)
3/7
fr.businessam.be/scandale-en-su…
science.org/content/articl…
No more delays. Judge Boasberg must be suspended immediately.
Impeachment is underway. He should not get to hear another case—this afternoon I led the effort to make that suspension happen.
My letter to Chief Judge Sri Srinivasan of the D.C. Circuit. 🧵
Impeachment is underway. He should not get to hear another case—this afternoon I led the effort to make that suspension happen.
My letter to Chief Judge Sri Srinivasan of the D.C. Circuit. 🧵
On November 4, articles of impeachment were filed against U.S. District Judge James E. Boasberg, Chief Judge of the United States District Court for the District of Columbia—following my call for his impeachment.
To discipline Judge Boasberg, a formal judicial misconduct complaint is required.
The Chief Judge of the Circuit—Srinivasan—is charged with ruling on such complaints.
On July 28, 2025, DOJ filed a judicial misconduct complaint against Judge Boasberg.
The Chief Judge of the Circuit—Srinivasan—is charged with ruling on such complaints.
On July 28, 2025, DOJ filed a judicial misconduct complaint against Judge Boasberg.
🛑 Thread: The Plated Table of Fear – Before the Storm (30 Tweets)
Scenario: The Kremlin, before 2021. The war in Ukraine has not yet begun.
1/30 The Cynical View of the Russian Populace
⚠️ WESTERN MISCONCEPTION CORRECTED: We must stop believing that 80% of Russians follow Putin out of love or deep loyalty. This thread shows: Putin and the inner circle at the luxurious table fear their own people more than NATO. The alleged "loyalty" is pure, fragile pragmatism—a wager on stability and personal profit. The fear of the day when Russians demand their own price is the true motive for the war. #RussiaPragmatic #KremlinContrast #FearOfFreedom
Scenario: The Kremlin, before 2021. The war in Ukraine has not yet begun.
1/30 The Cynical View of the Russian Populace
⚠️ WESTERN MISCONCEPTION CORRECTED: We must stop believing that 80% of Russians follow Putin out of love or deep loyalty. This thread shows: Putin and the inner circle at the luxurious table fear their own people more than NATO. The alleged "loyalty" is pure, fragile pragmatism—a wager on stability and personal profit. The fear of the day when Russians demand their own price is the true motive for the war. #RussiaPragmatic #KremlinContrast #FearOfFreedom
2/30: Putin's Deep Paranoia
Vladimir P. compulsively polishes a glass. Yevgeny Prigozhin discreetly serves wine. The report about the "West's freedom infecting the youth" confirms Putin's greatest fear. The fear of his own people is his true currency. He realizes: He must act now, before the youth unrest turns into a revolution and destroys his system of patronage.
Vladimir P. compulsively polishes a glass. Yevgeny Prigozhin discreetly serves wine. The report about the "West's freedom infecting the youth" confirms Putin's greatest fear. The fear of his own people is his true currency. He realizes: He must act now, before the youth unrest turns into a revolution and destroys his system of patronage.
3/30: The Banker as Propaganda Shield (Kovalchuk)
Yuri K. (Media Tsar) puts down a document—the latest polls on internal dissatisfaction. The propaganda is failing, he thinks in a panic. He must double down on the lies. The narrative must become so terrifying that Russians choose the regime out of fear of the West, rather than questioning the elite's corruption.
Yuri K. (Media Tsar) puts down a document—the latest polls on internal dissatisfaction. The propaganda is failing, he thinks in a panic. He must double down on the lies. The narrative must become so terrifying that Russians choose the regime out of fear of the West, rather than questioning the elite's corruption.
Con el NO a la Consulta perdió el #Ecuador NO el Gobierno‼️
@DanielNoboaOk
@NielsOlsenP
@JohnReimberg
@GianCarloLoffredo
@gabisommerfeld
🧵1️⃣/10
Ustedes cumplieron con lo q como pueblo pedimos antes d elegirles como Gobierno “Convocar a Consulta para cambiar la Constitución”
@DanielNoboaOk
@NielsOlsenP
@JohnReimberg
@GianCarloLoffredo
@gabisommerfeld
🧵1️⃣/10
Ustedes cumplieron con lo q como pueblo pedimos antes d elegirles como Gobierno “Convocar a Consulta para cambiar la Constitución”
2️⃣ Uds dentro del complicado marco han ido avanzando y tienen logros que apreciamos, en negociaciones internacionales, y eliminación d aranceles 🇺🇸 para más d 💯productos, desmantelar mafias d narcos y minería ilegal, atrapar bandidos y empezar a trasladarlos a alta seguridad.
3️⃣Sigan su trayectoria aunque la ignorancia les ponga trabas en sus acciones, ÁNIMO❣️
Reflexionando sobre el por qué del NO se puede perfeccionar el rumbo a seguir.
Reflexionando sobre el por qué del NO se puede perfeccionar el rumbo a seguir.
@smashbaals @christameric Also CERN.
@smashbaals @christameric @ThreadReaderApp unroll