Recent well liked threads
There are a lot of pharma agents celebrating on twitter recently because the now-conflicted @cochranecollab dropped their standards and published something on HPV vaccination they didn't understand.
To explain it you need to understand the difference between the two studies quoted.
The first (Bergman) analysed a bunch of real studies (including RCTs) and concluded that the effect on cancer couldn't be seen - despite nearly 20 years of follow up.
The second (Henschke) cherry picked a bunch of "real world data" studies and concluded that the vaccine prevented a gazillion cervical cancers, pretending that it analysed 132 million patient records. It did nothing of the sort. What it did was look at two studies, take out the bit where it showed that the vaccine increased the risk of cancer (Kjaer 2021, over 20s) - replicated in multiple country statistics, split them into three studies, ignore the other studies showing the opposite, and ignore the fact that none of this data is verifiable.
Notably, one of the major studies (Palmer 2024, which was found to be seriously flawed) has been excluded from the meta-analysis because it did not show a cancer benefit in the under 16 age group.
It is very difficult to "fix" a randomised controlled trial.
It is very easy to "fix" a meta-analysis of observational studies where the data is "not available".
There is a huge difference between "real" studies and "real world data" studies because the latter are cherry picked or even fully synthetic, and the authors don't have access to the data. They are produced by vested interests groups to sell a narrative.
This was the most corrupted review that Cochrane have ever performed and this time they shot themselves in the foot by contradicting their own reviews.
cochranelibrary.com/cdsr/doi/10.10…
@PGtzsche1 @MaryanneDemasi @SenatorAntic @DrJulieSladden @Fynnderella1 @missyTHX1138 @RWMaloneMD @RetsefL @BrokenTruthTV @RMConservative
To explain it you need to understand the difference between the two studies quoted.
The first (Bergman) analysed a bunch of real studies (including RCTs) and concluded that the effect on cancer couldn't be seen - despite nearly 20 years of follow up.
The second (Henschke) cherry picked a bunch of "real world data" studies and concluded that the vaccine prevented a gazillion cervical cancers, pretending that it analysed 132 million patient records. It did nothing of the sort. What it did was look at two studies, take out the bit where it showed that the vaccine increased the risk of cancer (Kjaer 2021, over 20s) - replicated in multiple country statistics, split them into three studies, ignore the other studies showing the opposite, and ignore the fact that none of this data is verifiable.
Notably, one of the major studies (Palmer 2024, which was found to be seriously flawed) has been excluded from the meta-analysis because it did not show a cancer benefit in the under 16 age group.
It is very difficult to "fix" a randomised controlled trial.
It is very easy to "fix" a meta-analysis of observational studies where the data is "not available".
There is a huge difference between "real" studies and "real world data" studies because the latter are cherry picked or even fully synthetic, and the authors don't have access to the data. They are produced by vested interests groups to sell a narrative.
This was the most corrupted review that Cochrane have ever performed and this time they shot themselves in the foot by contradicting their own reviews.
cochranelibrary.com/cdsr/doi/10.10…
@PGtzsche1 @MaryanneDemasi @SenatorAntic @DrJulieSladden @Fynnderella1 @missyTHX1138 @RWMaloneMD @RetsefL @BrokenTruthTV @RMConservative
"Scotland HPV vaccine study flawed" - explaining how the Scotland data on HPV was misrepresented to show an effect that wasn't real
blog.maryannedemasi.com/p/the-hpv-vacc…
blog.maryannedemasi.com/p/the-hpv-vacc…
How "real world data" papers claim to use electronic health records data but can't be verified and in many cases are not even real.
@ClareCraigPath
#Surgisphere #Penngate #EMRgate
arkmedic.info/p/pharma-hell-…
@ClareCraigPath
#Surgisphere #Penngate #EMRgate
arkmedic.info/p/pharma-hell-…
🧵Firma z Pragi sprzedawała Ukrainie chińskie drony po 20-krotnie zawyżonej cenie i nie płaciła podatków. Okazało się, że to Ukraińcy🇺🇦
Jak to się stało i na ile milionów udało się naciągnąć Ukraińcom Ukraińców? Zapraszam na tragikomiczny wątek o szmranym biznesie w czasach wojny 👇
1/6
Jak to się stało i na ile milionów udało się naciągnąć Ukraińcom Ukraińców? Zapraszam na tragikomiczny wątek o szmranym biznesie w czasach wojny 👇
1/6
🇨🇿Firma Reactive Drone z Pragi (Černý Most) jest oskarżona o poważne oszustwa podatkowe na kwotę co najmniej 130 milionów koron. Według ustaleń czeskich służb, firma kupiła chińskie drony za 36 milionów koron i sprzedała je ukraińskiej armii za 692 miliony. Tyle wygrać! Ale...
2/6
2/6
💲Według policji, firma przelała większość swoich zysków, a konkretnie 638 milionów koron, na chińskie konta i próbowała sztucznie zaniżać podstawę opodatkowania za pomocą fikcyjnych faktur. Podczas nalotu detektywi skonfiskowali z kont firmy 384 miliony koron, co powinno pokryć poniesione szkody.
3/6
3/6
Researchers at OpenAI, Anthropic, and Google quietly synced on something:
the prompts going viral on Twitter aren’t the ones moving the frontier.
The breakthroughs come from 7 obscure techniques most people have never tried.
If you want to see how the pros are actually steering these models:
the prompts going viral on Twitter aren’t the ones moving the frontier.
The breakthroughs come from 7 obscure techniques most people have never tried.
If you want to see how the pros are actually steering these models:
1. Constraint-Stacking Prompts
Experts don’t ask the model to “write better.”
They stack constraints that force higher-order reasoning. The model becomes sharper because it has to satisfy multiple conditions at once.
Example:
“Rewrite this paragraph with
• a grade 5 clarity level
• 2 insights that a senior engineer would respect
• a logical chain with each sentence adding new information
• a single takeaway in the final line”
This forces the model to optimize for clarity, depth, structure, and purpose all at once.
Experts don’t ask the model to “write better.”
They stack constraints that force higher-order reasoning. The model becomes sharper because it has to satisfy multiple conditions at once.
Example:
“Rewrite this paragraph with
• a grade 5 clarity level
• 2 insights that a senior engineer would respect
• a logical chain with each sentence adding new information
• a single takeaway in the final line”
This forces the model to optimize for clarity, depth, structure, and purpose all at once.
2. Reversal Prompts
Instead of asking the model to “give the answer,” experts ask it to predict the wrong answer first, then correct itself.
This activates contrastive reasoning.
Example:
“Give me the worst possible explanation of vector embeddings.
Then rewrite it into the best possible explanation.
Highlight exactly what changed and why.”
The model becomes self-corrective, analytical, and far more precise.
Instead of asking the model to “give the answer,” experts ask it to predict the wrong answer first, then correct itself.
This activates contrastive reasoning.
Example:
“Give me the worst possible explanation of vector embeddings.
Then rewrite it into the best possible explanation.
Highlight exactly what changed and why.”
The model becomes self-corrective, analytical, and far more precise.
The CIAMafia installed Trump and they are now going to remove him.
They are also going to take down the KremlinMafia by a few notches.
And the LikudMafia by several more.
They are also going to take down the KremlinMafia by a few notches.
And the LikudMafia by several more.
@_SERAPH But pieces get moved on the gameboard that are not moved by the players we can see. All we can discern of this entity is negative space.
If you can bear with me, I'll go thru my educational progress. I first thought that the Russians had installed Trump - it was obvious that
If you can bear with me, I'll go thru my educational progress. I first thought that the Russians had installed Trump - it was obvious that
@_SERAPH couldn't pull it off himself. One clue was the removal of GOP protection for Ukraine from the 2016 platform.
But then I learned that Trump was part of the NYC Italian-American Mafia, and his father was also - they were a "front" for them. But then I learned about Trump's trips
But then I learned that Trump was part of the NYC Italian-American Mafia, and his father was also - they were a "front" for them. But then I learned about Trump's trips
🚨EXCLUSIVE
A major software company just stopped using a far-left smear factory to blacklist conservatives.
This is the latest domino to fall, suggesting Corporate America is finally seeing the light about the Southern Poverty Law Center.
🧵1/15
dailysignal.com/2025/11/26/exc…
A major software company just stopped using a far-left smear factory to blacklist conservatives.
This is the latest domino to fall, suggesting Corporate America is finally seeing the light about the Southern Poverty Law Center.
🧵1/15
dailysignal.com/2025/11/26/exc…
Salesforce, a 75K-employee firm, uses Benevity to help workers make an impact. Benevity helps employees support causes they believe in, donating before taxes, matching grants, and volunteering. But Salesforce blacklisted conservatives using SPLC.
🧵2/15
🧵2/15
SPLC leverages its reputation of suing KKK groups into bankruptcy, putting out a "hate map" that plots mainstream conservative and Christian groups alongside Klan chapters. How do you get on the map? By opposing the SPLC's agenda.
🧵3/15
🧵3/15
If you still believe COVID left the population “unchanged”, open a dating app. It sounds absurd, but stay with me here.
The cognitive bluntness is so widespread that the dating platforms themselves have had to acknowledge behavioural deterioration since 2020.
It’s not subtle🧵
The cognitive bluntness is so widespread that the dating platforms themselves have had to acknowledge behavioural deterioration since 2020.
It’s not subtle🧵
Since 2020, apps report the same pattern: shorter messages, less reciprocity, fewer follow-ups, lower meet-up rates & a collapse in sustained conversational ability.
This isn’t just “people being tired”. It’s a measurable degradation of attention, initiative & social cognition.
This isn’t just “people being tired”. It’s a measurable degradation of attention, initiative & social cognition.
The cause?
- repeated COVID infections impairing cognitive stamina/reward processing
- chronic low-grade fatigue
- dopamine systems altered by COVID/crises
- widespread emotional numbing
- increased avoidance as default coping mechanism
All the above = social “flatlining”
- repeated COVID infections impairing cognitive stamina/reward processing
- chronic low-grade fatigue
- dopamine systems altered by COVID/crises
- widespread emotional numbing
- increased avoidance as default coping mechanism
All the above = social “flatlining”
So this is the new message out there:
“You will be held accountable for your crimes.”
I went to church recently. Going in and coming out, women with bullhorns screamed that exact line at me… and plenty more.
But here’s the truth: everyone can be held accountable for crimes if they’re actually committing them. Elections SHOULDN’T matter in this, but they do now.
That’s not what these people are saying.
What they are really saying is: “When power changes hands, vengeance changes hands.”
And this is exactly what @LaraLogan has been warning about when she talks about election integrity. It’s not an abstract issue. It’s the foundation of whether a republic survives or collapses.
America was built on the assumption that we would remain a moral people. Under that assumption, elections shifted policy. Now elections determine who holds the sword… and who it will be used against.
We are losing morality, therefore we are headed for authoritarianism. And whether you like hearing it or not, it is inevitable. Whether it’s left or right, it is inevitable.
The only off-ramp is restoring trust in our elections. Because if a corrupt political machine can manipulate outcomes, import new voters, and reward radicals for burning the country down, why would they ever stop? Power unrestrained accelerates until it consumes everything in front of it.
This should never have been a partisan question. But critics who defend the corruption will call me fascist, because order to the lawless always looks like tyranny.
Pass sweeping election reforms. Normalize the country. Or lose it forever.
Accelerationism is real. And the half of the country that loses at the ballot box isn’t planning to merely reverse your policies.
They’re planning to come after you.
“You will be held accountable for your crimes.”
I went to church recently. Going in and coming out, women with bullhorns screamed that exact line at me… and plenty more.
But here’s the truth: everyone can be held accountable for crimes if they’re actually committing them. Elections SHOULDN’T matter in this, but they do now.
That’s not what these people are saying.
What they are really saying is: “When power changes hands, vengeance changes hands.”
And this is exactly what @LaraLogan has been warning about when she talks about election integrity. It’s not an abstract issue. It’s the foundation of whether a republic survives or collapses.
America was built on the assumption that we would remain a moral people. Under that assumption, elections shifted policy. Now elections determine who holds the sword… and who it will be used against.
We are losing morality, therefore we are headed for authoritarianism. And whether you like hearing it or not, it is inevitable. Whether it’s left or right, it is inevitable.
The only off-ramp is restoring trust in our elections. Because if a corrupt political machine can manipulate outcomes, import new voters, and reward radicals for burning the country down, why would they ever stop? Power unrestrained accelerates until it consumes everything in front of it.
This should never have been a partisan question. But critics who defend the corruption will call me fascist, because order to the lawless always looks like tyranny.
Pass sweeping election reforms. Normalize the country. Or lose it forever.
Accelerationism is real. And the half of the country that loses at the ballot box isn’t planning to merely reverse your policies.
They’re planning to come after you.
I’d like to point out that the women screaming at me didn’t even know who I was. I was wearing a suit. So my mere appearance gave across the vibe to them that I was an enemy.
That’s where we’re at. And it was the first time I’ve ever encountered in real life what I’ve seen here.
That’s where we’re at. And it was the first time I’ve ever encountered in real life what I’ve seen here.
A new 3-year scRNA-seq study shows something striking. Some people after COVID still carry an immune profile that looks like accelerated aging - low naive T cells and persistent activation of pathogenic Th17. Not a long-COVID cohort, but biologically very close🧵
The study didn’t select people with long COVID.
It followed 47 individuals after COVID-19 for 3 years - and some symptoms were reported within the cohort, allowing the authors to examine symptom-associated immune signals without defining a long-COVID subgroup.
It followed 47 individuals after COVID-19 for 3 years - and some symptoms were reported within the cohort, allowing the authors to examine symptom-associated immune signals without defining a long-COVID subgroup.
The first major finding.
Even after 3 years, three key protective cell types remain significantly reduced
naive CD4 T cells
naive CD8 T cells
SLC4A10+ MAIT cells
This pattern is normally associated with immunosenescence.
Even after 3 years, three key protective cell types remain significantly reduced
naive CD4 T cells
naive CD8 T cells
SLC4A10+ MAIT cells
This pattern is normally associated with immunosenescence.
Hehe nimekumbuka hapo September when I was attending an old boys meeting in my former highschool met with some of these older dudes who are in the same field as me . Nikawauliza where best I can apply for a job and which other courses naeza fanya ili I become more marketable
Dudes after finding out I had recently graduated waliniambia ata sijakaa sana na sijateseka vizuri.
Les fortifications peuvent-elles changer le cours de la guerre en faveur de l'Ukraine 🇺🇦 ?
Malgré un manque cruel d'infanterie pour les occuper, les obstacles ukrainiens sont de plus en plus nombreux et conséquents, ralentissant la progression russe 🇷🇺
🧵THREAD🧵1/23 ⬇️
Malgré un manque cruel d'infanterie pour les occuper, les obstacles ukrainiens sont de plus en plus nombreux et conséquents, ralentissant la progression russe 🇷🇺
🧵THREAD🧵1/23 ⬇️
Cela fait plus de 3 ans que j'analyse régulièrement la question des lignes de défense en Ukraine.
J'ai cartographié la quasi-totalité de ces défenses, analysé leurs résultats, leurs échecs et les récentes évolutions.
J'ai cartographié la quasi-totalité de ces défenses, analysé leurs résultats, leurs échecs et les récentes évolutions.
D'abord avec cette carte, vous pouvez voir en rouge les fortifications creusées en 2025 et en vert le territoire pris par l'armée russe la même année.
Pour la première fois, nous allons le voir, ces fortifications sont continues, bien préparées et nombreuses.
Pour la première fois, nous allons le voir, ces fortifications sont continues, bien préparées et nombreuses.
1/🧵The Solana ecosystem continues to focus on speed and scalability, generating $115B+ in 30d DEX volume.
Yet efficient lending markets don't exist for majority of that volume.
LPs, traders and builders still face the same issues DeFi promised to fix ↓
Yet efficient lending markets don't exist for majority of that volume.
LPs, traders and builders still face the same issues DeFi promised to fix ↓
2/ Start with LPs:
LPs now supply billions across AMMs like Raydium, Orca, Meteora, Phoenix.
Yet 70% of that capital sits still earning only swap fees, so they take the risk of a lending market participant while being in a passive AMM position.
Impermanent loss compounds the issue as even high-volume pools often see negative LP outcomes over time.
LPs now supply billions across AMMs like Raydium, Orca, Meteora, Phoenix.
Yet 70% of that capital sits still earning only swap fees, so they take the risk of a lending market participant while being in a passive AMM position.
Impermanent loss compounds the issue as even high-volume pools often see negative LP outcomes over time.
3/ Borrow demand is split across many venues like Drift, Kamino, Jupiter Lend, etc.
Each protocol handles risk differently, routes capital differently, and while having the ability to create certain lending markets, still relies on external oracle data feeds and routing algorithms.
Omnipair knows LPs do not deserve that at all.
Each protocol handles risk differently, routes capital differently, and while having the ability to create certain lending markets, still relies on external oracle data feeds and routing algorithms.
Omnipair knows LPs do not deserve that at all.
For weeks this summer I said Travis Kalanick should run Opendoor.
People laughed.
But they missed the point:
Opendoor needed a builder — not a caretaker.
A founder with aggression, velocity, and vision.
The market treated that as non-consensus.
It was actually obvious.
People laughed.
But they missed the point:
Opendoor needed a builder — not a caretaker.
A founder with aggression, velocity, and vision.
The market treated that as non-consensus.
It was actually obvious.
Travis would have been great.
He understands operational violence.
He understands marketplaces.
He understands refusing to die.
The “Travis era” at Uber was pure asymmetric execution — exactly what OPEN needed.
And for a while, I believed he was the only one who could pull it off.
He understands operational violence.
He understands marketplaces.
He understands refusing to die.
The “Travis era” at Uber was pure asymmetric execution — exactly what OPEN needed.
And for a while, I believed he was the only one who could pull it off.
But then something happened the market didn’t predict:
Kaz Nejatian stepped in — and he carries the same founder aggression,
but with a far deeper understanding of what Opendoor can become.
Kaz sees the full platform.
Not just iBuying.
Not just spreads.
The software company inside the real-estate shell.
And he’s executing like someone who has nothing to lose.
Kaz Nejatian stepped in — and he carries the same founder aggression,
but with a far deeper understanding of what Opendoor can become.
Kaz sees the full platform.
Not just iBuying.
Not just spreads.
The software company inside the real-estate shell.
And he’s executing like someone who has nothing to lose.