Recent well liked threads
What does the writing of Katy Perry, Hemingway, and The Bible have in common?
Mark Forsyth has the answer. He studied history's greatest writers and noticed how they used the same rhetorical formulas.
Here's what you need to know:
1. The formulas are timeless (and still work).
2. Where to begin? Try taking the last word of one sentence and repeating it as the first word in the next. It gives the illusion of logic. Like this one from Yoda: "Fear leads to anger. Anger leads to hatred. Hatred leads to suffering."
3. An example from Malcolm X: "Once you change your philosophy, you change your thought pattern. Once you change your thought pattern, you change your attitude. Once you change your attitude, it changes your behavior pattern and then you go on into some action."
4. It's a mystery why, but people love to hear a string of words that begins with the same letter. "Two to Tango" is a heck of a lot more memorable than "Two to Waltz."
5. From his book, Elements of Eloquence: "Adjectives in English absolutely have to be in this order: opinion-size-age-shape-colour-origin-material-purpose Noun."
6. People will tell you to write only what's necessary, but endless repetition can be a way to emphasize something. Katy Perry's repetition of opposites is logically unnecessary, but it works: "'Cause you're hot then you're cold, You're yes then you're no, You're in then you're out, You're up then you're down, You're wrong when it's right, It's black and it's white, We fight, we break up, We kiss, we make up."
7. Wedding vows have the same kind of repetition: "For better or for worse, for richer or poorer, in sickness and in health..."
8. JFK leaned on a rhetorical device called a Chiasmus, where you take the first half of a sentence and say it backward. You see it in sentences like "Mankind must put an end to war—or war will put an end to mankind" and "Ask not what your country can do for you—ask what you can do for your country."
9. I like the Chiasmus because it's so easy to implement. Here's another example of a Chiasmus, like when Cormac McCarthy wrote: "You forget what you want to remember, and you remember what you want to forget."
10. Language is ruled by the mob. Doesn't matter what the committees think. If everybody uses a word in a certain way, then that's what it means.
11. Most of Shakespeare's famous lines are simply examples of famous formulas.
12. Shakespeare often "stole" content from other people, but he improved what he stole by using rhetorical formulas and figures of speech. Mark insists that he had Thomas North’s translation of Plutarch open while writing Julius Caesar.
13. Write two things that connect, then add a twist for the third thing. The magic comes from the surprise. An example is: "Lies, damned lies, and statistics." Another is: "Life, liberty, and the pursuit of happiness."
14. Sometimes, the things that stick will simply surprise you. One of the most famous lines in film history only has three words: "Bond. James Bond."
15. The James Bond-style line is called a Diacope. Other examples are "Burn, baby, burn" and "Zed’s dead, baby, Zed’s dead."
If nerding out on beautiful writing is your thing, you will love this episode. By the time you're done listening, you'll have X-ray vision for the English language.
I've shared the full interview with @Inkyfool below.
You can also listen on Apple or Spotify, or watch on YouTube. Check the links in the reply tweets.
Mark Forsyth has the answer. He studied history's greatest writers and noticed how they used the same rhetorical formulas.
Here's what you need to know:
1. The formulas are timeless (and still work).
2. Where to begin? Try taking the last word of one sentence and repeating it as the first word in the next. It gives the illusion of logic. Like this one from Yoda: "Fear leads to anger. Anger leads to hatred. Hatred leads to suffering."
3. An example from Malcolm X: "Once you change your philosophy, you change your thought pattern. Once you change your thought pattern, you change your attitude. Once you change your attitude, it changes your behavior pattern and then you go on into some action."
4. It's a mystery why, but people love to hear a string of words that begins with the same letter. "Two to Tango" is a heck of a lot more memorable than "Two to Waltz."
5. From his book, Elements of Eloquence: "Adjectives in English absolutely have to be in this order: opinion-size-age-shape-colour-origin-material-purpose Noun."
6. People will tell you to write only what's necessary, but endless repetition can be a way to emphasize something. Katy Perry's repetition of opposites is logically unnecessary, but it works: "'Cause you're hot then you're cold, You're yes then you're no, You're in then you're out, You're up then you're down, You're wrong when it's right, It's black and it's white, We fight, we break up, We kiss, we make up."
7. Wedding vows have the same kind of repetition: "For better or for worse, for richer or poorer, in sickness and in health..."
8. JFK leaned on a rhetorical device called a Chiasmus, where you take the first half of a sentence and say it backward. You see it in sentences like "Mankind must put an end to war—or war will put an end to mankind" and "Ask not what your country can do for you—ask what you can do for your country."
9. I like the Chiasmus because it's so easy to implement. Here's another example of a Chiasmus, like when Cormac McCarthy wrote: "You forget what you want to remember, and you remember what you want to forget."
10. Language is ruled by the mob. Doesn't matter what the committees think. If everybody uses a word in a certain way, then that's what it means.
11. Most of Shakespeare's famous lines are simply examples of famous formulas.
12. Shakespeare often "stole" content from other people, but he improved what he stole by using rhetorical formulas and figures of speech. Mark insists that he had Thomas North’s translation of Plutarch open while writing Julius Caesar.
13. Write two things that connect, then add a twist for the third thing. The magic comes from the surprise. An example is: "Lies, damned lies, and statistics." Another is: "Life, liberty, and the pursuit of happiness."
14. Sometimes, the things that stick will simply surprise you. One of the most famous lines in film history only has three words: "Bond. James Bond."
15. The James Bond-style line is called a Diacope. Other examples are "Burn, baby, burn" and "Zed’s dead, baby, Zed’s dead."
If nerding out on beautiful writing is your thing, you will love this episode. By the time you're done listening, you'll have X-ray vision for the English language.
I've shared the full interview with @Inkyfool below.
You can also listen on Apple or Spotify, or watch on YouTube. Check the links in the reply tweets.
Here's the link to Apple and Spotify if you'd rather listen there...
Apple: podcasts.apple.com/us/podcast/how…
Spotify: open.spotify.com/episode/0QQ8bf…
Apple: podcasts.apple.com/us/podcast/how…
Spotify: open.spotify.com/episode/0QQ8bf…
If long-form interviews on Twitter aren't your thing, you can watch the full thing on YouTube.
Will somebody please explain to me how, with the Strait of Hormuz a no-go-zone for the U.S. Navy, and our warships driven out of the Persian Gulf, we can support a USMC amphibious landing on Kharg Island, 750 miles from the eastern tip of Oman?🧵
Is the Tripoli Amphibious Ready Group going to storm into the Persian Gulf, where our Burke-class destroyers won't go? Obviously not. This idea is insane. How about by helo and tilt-rotor? Out of range.
What if they stage in Kuwait or Saudi Arabia for helo and Osprey lifts across the Gulf? Russia and China will tell Iran where to aim their drones and missiles while the force is assembling.
Maybe a mass paradrop? Straight into an "Alamo" siege. Great idea. Not.
What if the Marines just capture some of those "small" islands in the Strait of Hormuz? Qeshm is bigger than Okinawa. Larak is bigger than Iwo Jima. Any idea how many Marines and Soldiers it took to conquer just those 2 islands, at what cost in KIA and WIA?
I keep reading absolute MORONS on X telling how some A-10s are "softening up" an area larger than South Vietnam, so that a few thousand Marines can attack and hold . . . what?
It's as if space aliens studying only still images had no sense of scale of earth creatures, and thought a mouse could eat an elephant. It boggles my mind.
Is the Tripoli Amphibious Ready Group going to storm into the Persian Gulf, where our Burke-class destroyers won't go? Obviously not. This idea is insane. How about by helo and tilt-rotor? Out of range.
What if they stage in Kuwait or Saudi Arabia for helo and Osprey lifts across the Gulf? Russia and China will tell Iran where to aim their drones and missiles while the force is assembling.
Maybe a mass paradrop? Straight into an "Alamo" siege. Great idea. Not.
What if the Marines just capture some of those "small" islands in the Strait of Hormuz? Qeshm is bigger than Okinawa. Larak is bigger than Iwo Jima. Any idea how many Marines and Soldiers it took to conquer just those 2 islands, at what cost in KIA and WIA?
I keep reading absolute MORONS on X telling how some A-10s are "softening up" an area larger than South Vietnam, so that a few thousand Marines can attack and hold . . . what?
It's as if space aliens studying only still images had no sense of scale of earth creatures, and thought a mouse could eat an elephant. It boggles my mind.
2.
3.
5 CONVOS That Lead To S3X:
1. Tell me about your childhood
1. Tell me about your childhood
1. Tell me about your childhood
This isn't about facts; it’s about emotions.
When she talks about her younger self, she’s letting you into her most vulnerable state.
You aren't just a date anymore; you are a part of her history.
This isn't about facts; it’s about emotions.
When she talks about her younger self, she’s letting you into her most vulnerable state.
You aren't just a date anymore; you are a part of her history.
2. The "Guilty Pleasure" Pivot
Ask her what she loves that she’s usually "too embarrassed" to admit.
When she shares it, don't judge—tease her.
This creates a "Secret Society" of two.
Once she shares a secret with you, the psychological barrier to sharing her body crumbles
Ask her what she loves that she’s usually "too embarrassed" to admit.
When she shares it, don't judge—tease her.
This creates a "Secret Society" of two.
Once she shares a secret with you, the psychological barrier to sharing her body crumbles
HOW To Flirt Over TEXT
(Like a playb0y)
1. Speak like you already have her
(Like a playb0y)
1. Speak like you already have her
Flirt like the outcome is inevitable.
Like she’s already into you.
“Stop staring. I know I look good today.”
“Your imaginary crush on me is getting outta hand.”
Women fantasize about the man who already assumes the win.
Like she’s already into you.
“Stop staring. I know I look good today.”
“Your imaginary crush on me is getting outta hand.”
Women fantasize about the man who already assumes the win.
2. Tease, don’t please
Don’t start with “hey beautiful” like a loser.
Start with something that makes her pause and feel something.
“You strike me as the kind who ruins men’s lives and smiles while doing it.”
Make it spicy. Not submissive.
Don’t start with “hey beautiful” like a loser.
Start with something that makes her pause and feel something.
“You strike me as the kind who ruins men’s lives and smiles while doing it.”
Make it spicy. Not submissive.
José Ortega y Gasset watched Europe triple its population in a single century and asked:
What happens when the average man, raised in unprecedented comfort, decides he owes *nothing* to the civilization that made his life possible?
His answer, written in 1930, predicted the exact world we live in today. (thread) 🧵
What happens when the average man, raised in unprecedented comfort, decides he owes *nothing* to the civilization that made his life possible?
His answer, written in 1930, predicted the exact world we live in today. (thread) 🧵
Ortega divided humanity into two types.
Type 1: The noble man. Someone who holds himself to standards beyond what is required. He seeks difficulty. He imposes obligations on himself. Life for him is discipline and striving.
Type 2: The mass-man. Someone content to be identical to everyone else. He demands nothing of himself. He floats. He thinks nothing of watching 5+ hours of TV on a Saturday afternoon.
Type 1: The noble man. Someone who holds himself to standards beyond what is required. He seeks difficulty. He imposes obligations on himself. Life for him is discipline and striving.
Type 2: The mass-man. Someone content to be identical to everyone else. He demands nothing of himself. He floats. He thinks nothing of watching 5+ hours of TV on a Saturday afternoon.
The mass-man is not defined by income or job title. A factory worker can have a noble soul. A professor can be pure mass-man.
The test is simple:
Does this person believe he has the right to opinions he never earned through effort? Does he feel complete without ever having stretched beyond what comes easy?
If yes, you are looking at the mass-man.
The test is simple:
Does this person believe he has the right to opinions he never earned through effort? Does he feel complete without ever having stretched beyond what comes easy?
If yes, you are looking at the mass-man.
How to Quit a Job You Hate. How to Build Your Own Trading Bot.A Complete Guide.I didn't go to Harvard, i just learned to use AI the way it was meant to be used
Why Manual Trading Loses to Algorithms
Stanford research shows that the amygdala - the brain's emotional centerx.com/i/article/2035502840244781056
Why Manual Trading Loses to Algorithms
Stanford research shows that the amygdala - the brain's emotional centerx.com/i/article/2035502840244781056
Birmingham. 2025.
Government inspectors found that supervisors at West Midlands Police had an unofficial written procedure.
Child assaults — regardless of who the perpetrator was.
Child neglect.
Peer-on-peer child sexual assaults.
Do not investigate.
It is in the HMIC national child protection inspection report published November 2025. 🧵
Government inspectors found that supervisors at West Midlands Police had an unofficial written procedure.
Child assaults — regardless of who the perpetrator was.
Child neglect.
Peer-on-peer child sexual assaults.
Do not investigate.
It is in the HMIC national child protection inspection report published November 2025. 🧵
For context before we go further.
In 2010 West Midlands Police produced a confidential CSE intelligence profile. It identified 139 victims. 79 percent of suspects were Asian.
It was suppressed.
Released only after a Birmingham Mail FOI request in 2015.
Keep that in mind.
Source: expressandstar.com/news/2015/06/2…
In 2010 West Midlands Police produced a confidential CSE intelligence profile. It identified 139 victims. 79 percent of suspects were Asian.
It was suppressed.
Released only after a Birmingham Mail FOI request in 2015.
Keep that in mind.
Source: expressandstar.com/news/2015/06/2…
The report states inspectors found supervisors in Birmingham’s central referral unit “routinely using a procedure that wasn’t in the force’s guidance.”
The procedure directed that child assaults with what the force described as “transitory or low-level injury” — regardless of who the perpetrator was — “low-level neglect,” and child “peer-on-peer sexual assaults” should all be recorded as crimes of “child cruelty.”
“The procedure recommended no police investigation in these cases.”
The procedure directed that child assaults with what the force described as “transitory or low-level injury” — regardless of who the perpetrator was — “low-level neglect,” and child “peer-on-peer sexual assaults” should all be recorded as crimes of “child cruelty.”
“The procedure recommended no police investigation in these cases.”
Over $1 BILLION in federal student aid fraud has been stopped since January 2025.
This is what was uncovered: 🧵
This is what was uncovered: 🧵
Nearly $90 million in fraudulent aid had already been disbursed.
More than $30 million went to individuals who were deceased.
More than $40 million went to bots posing as students.
More than $30 million went to individuals who were deceased.
More than $40 million went to bots posing as students.
Fraudsters used AI-generated identities and stolen personal information to create applications that appeared legitimate.
These were fake students enrolling to access real money.
These were fake students enrolling to access real money.
Wharton’s latest AI study points to a hard truth: “AI writes, humans review” model is breaking down
Why "just review the AI output" doesn't work anymore, our brains literally give up.
We have started doing "Cognitive Surrender" to AI - Wharton’s latest AI study points to a hard truth: reviewing AI output is not a reliable safeguard when cognition itself starts to defer to the machine.when you stop verifying what the AI tells you, and you don't even realize you stopped. It's different from offloading, like using a calculator.
With offloading you know the tool did the work. With surrender, your brain recodes the AI's answer as YOUR judgment. You genuinely believe you thought it through yourself.
Says AI is becoming a 3rd thinking system, and people often trust it too easily.
You know Kahneman's System 1 (fast intuition) and System 2 (slow analysis)? They're saying AI is now System 3, an external cognitive system that operates outside your brain. And when you use it enough, something happens that they call Cognitive Surrender.
Cognitive surrender is trickier: AI gives an answer, you stop really questioning it, and your brain starts treating that output as your own conclusion. It does not feel outsourced. It feels self-generated.
The data makes it hard to brush off. Across 3 preregistered studies with 1,372 participants and 9,593 trials, people turned to AI on over 50% of questions.
In Study 1, when AI was correct, people followed it 92.7% of the time. When it was wrong, they still followed it 79.8% of the time.
Without AI, baseline accuracy was 45.8%. With correct AI, it jumped to 71.0%. With incorrect AI, it dropped to 31.5%, worse than having no AI. Access to AI also boosted confidence by 11.7 percentage points, even when the answers were wrong.
Human review is supposed to be the safety net. But this research suggests the safety net has a hole in it: people do not just miss bad AI output; they become more confident in it.
Time pressure did not eliminate the effect. Incentives and feedback reduced it but did not remove it. And the people most resistant tended to score higher on fluid intelligence and need for cognition. That makes this feel less like a laziness problem and more like a cognitive architecture problem.
Why "just review the AI output" doesn't work anymore, our brains literally give up.
We have started doing "Cognitive Surrender" to AI - Wharton’s latest AI study points to a hard truth: reviewing AI output is not a reliable safeguard when cognition itself starts to defer to the machine.when you stop verifying what the AI tells you, and you don't even realize you stopped. It's different from offloading, like using a calculator.
With offloading you know the tool did the work. With surrender, your brain recodes the AI's answer as YOUR judgment. You genuinely believe you thought it through yourself.
Says AI is becoming a 3rd thinking system, and people often trust it too easily.
You know Kahneman's System 1 (fast intuition) and System 2 (slow analysis)? They're saying AI is now System 3, an external cognitive system that operates outside your brain. And when you use it enough, something happens that they call Cognitive Surrender.
Cognitive surrender is trickier: AI gives an answer, you stop really questioning it, and your brain starts treating that output as your own conclusion. It does not feel outsourced. It feels self-generated.
The data makes it hard to brush off. Across 3 preregistered studies with 1,372 participants and 9,593 trials, people turned to AI on over 50% of questions.
In Study 1, when AI was correct, people followed it 92.7% of the time. When it was wrong, they still followed it 79.8% of the time.
Without AI, baseline accuracy was 45.8%. With correct AI, it jumped to 71.0%. With incorrect AI, it dropped to 31.5%, worse than having no AI. Access to AI also boosted confidence by 11.7 percentage points, even when the answers were wrong.
Human review is supposed to be the safety net. But this research suggests the safety net has a hole in it: people do not just miss bad AI output; they become more confident in it.
Time pressure did not eliminate the effect. Incentives and feedback reduced it but did not remove it. And the people most resistant tended to score higher on fluid intelligence and need for cognition. That makes this feel less like a laziness problem and more like a cognitive architecture problem.
Mormon Women for Ethical Government (@mormonweg) is quite upset that I dedicated a presentation to them to a Utahn Republican Women's group. They called it "absolutely false."
I don't know what they are alleging is false, like Bill Kristol is among their biggest donors (as @labtechleigh found), or that their co-executive director Jen Thomas represents MWEG in a meeting series as part of a fractal ecosystem to transform America's governance.
But in the spirit of last year's thread on @CODEPINK , I will do a 100% factual, zero opinion, receipt-based thread on MWEG to clear the air. As MWEG said - "be kind, but be direct."
💕💕💕💕
I don't know what they are alleging is false, like Bill Kristol is among their biggest donors (as @labtechleigh found), or that their co-executive director Jen Thomas represents MWEG in a meeting series as part of a fractal ecosystem to transform America's governance.
But in the spirit of last year's thread on @CODEPINK , I will do a 100% factual, zero opinion, receipt-based thread on MWEG to clear the air. As MWEG said - "be kind, but be direct."
💕💕💕💕
@mormonweg FACT: MWEG reported a jump from 437K to 1.3M in one year from grants.
@mormonweg FACT: Bill Kristol's Group, Defending Democracy Together Institute, is a large donor at 150K for at least 2 years going. What relationship does Kristol have to LDS women?
بلاعنوان۔۔۔
صرف شیر افضل بکا ہے یا سارے مروت بک گئے ہیں۔؟
ایران جنگ کے شور میں کمپنی صرف بندوقوں کو ٹاکی شاکی مار رہی ہے یا اپنا اصلی کام یعنی عمران خان مٹاؤ پروگرام بھی جاری رکھے ہوئے ہے۔۔؟
بات ایک کال سے شروع ہوئ جو ہماری ایک رشتہ دار کی جانب سے موصول ہوئ۔ وہ بحریہ کراچی
صرف شیر افضل بکا ہے یا سارے مروت بک گئے ہیں۔؟
ایران جنگ کے شور میں کمپنی صرف بندوقوں کو ٹاکی شاکی مار رہی ہے یا اپنا اصلی کام یعنی عمران خان مٹاؤ پروگرام بھی جاری رکھے ہوئے ہے۔۔؟
بات ایک کال سے شروع ہوئ جو ہماری ایک رشتہ دار کی جانب سے موصول ہوئ۔ وہ بحریہ کراچی
میں رہتی ہیں عید کے روز وہ اپنی ہی کالونی میں Hostage بنی رہیں باہر نہیں نکل سکتی تھیں کیونکہ باہر بظاہر کے پی سے آئے پٹھانوں نے وہ طوفان بدتمیزی اور غلاظت مچائ ہوئ تھی کہ خدا کی پناہ۔
انکے بقول یہ صرف کراچی میں نہیں ہو رہا تھا اس روز میانوالی ملتان لاہور مری
انکے بقول یہ صرف کراچی میں نہیں ہو رہا تھا اس روز میانوالی ملتان لاہور مری
راولپنڈی سمیت پنجاب کے کئی شہروں میں تمام تفریح گاہیں نو گو ایریا بنی ہوئیں تھیں کیونکہ کچھ اخری لیول کے جنگلی گنوار پٹھان نا بچوں کو چھوڑ رہے تھے نا ہی عورتوں کو ہر جنس کو بلا تخصیص ہراساں کیا جا رہا تھا۔
اور ہر جگہ پلے بک ایک جیسی تھی۔
کوسٹروں ٹرکوں میں بھر کر آئ یا لائ گئ
اور ہر جگہ پلے بک ایک جیسی تھی۔
کوسٹروں ٹرکوں میں بھر کر آئ یا لائ گئ
Wie anders de oorlog van 🇺🇸 en 🇮🇱 tegen #Iran laten duiden dan Peyman #Jafari, het (oud-)kopstuk van de Internationale Socialisten? Zou Jeroen #Wollaars daar bedenkingen bij hebben? Voor zover @wol die heeft, houdt hij zijn mond... De semi-ambtenaar heeft een riant salaris. 1/5
"Peyman Jafari, dank voor vanavond", aldus de NOS'er, waarop de marxist met "Graag gedaan" reageert. Het is onwaarschijnlijk dat de vaste "Iran-deskundige" van #Nieuwsuur gratis commentaar geeft. Hoeveel belastinggeld zou hij ondertussen al dankzij @wol & co hebben gekregen? 2/5
@wol De naam "Internationale Socialisten" wekt bij sommige lezers wellicht de indruk dat het om een samenwerkingsverband van partijen als de SP gaat. Dat is echter niet het geval. Het betreft een extreem-linkse organisatie, die onder meer anti-kapitalistisch en anti-Westers is. 3/5
hi ai goes beyond typical automation tools, adapting to unique customer needs with AI-driven email responses. It's not just about efficiency, it's about personalization. #AI #CustomerSupport
topai.tools/t/hiaireply-com
topai.tools/t/hiaireply-com
@threadreaderapp unroll
1. Question asked about deuterium exhaust on Chromosome #2
2. ANSWER: Via the blood. The fact that deuterium is three times high concentration of glucose proves my point that mammals are costly in time and not energy. Glucose is the energy intermediate for glycolysis. Deuterium destroys TCA and urea cycling in the matrix when deuterium is in the INJs ruining cristae alignment via the KIE. Adult RBC's have no mitochondrial because of this relationship. Child with fetal Hb cannot handle high deuterium states and this is why they can die of SIDS when they are fed or given too much deuterium from any route.
3. Here is the breakdown of those two specific mechanisms:
1. Transport from Mitochondria to Pancreas
Deuterium isn't transported as a free ion (D+) through the blood; that would be inefficient and potentially toxic. Instead, it moves via metabolic water and substrate cycling:
TCA Cycle Clearance: Mitochondria in cells throughout the body produce "metabolic water" as a byproduct of ATP production. If the mitochondria are struggling, they produce water with a higher deuterium-to-protium ratio.
The Glucose/Bicarbonate Shunt: Excess deuterium is often incorporated into organic molecules (like glucose or amino acids) or stays in the plasma as part of the bicarbonate buffer system (HCO−3).
The Pancreatic Pull: The pancreas has an incredibly high metabolic rate and blood flow. It "collects" these deuterated compounds from the circulation to synthesize digestive enzymes and bicarbonate. When the pancreas is functioning optimally, it shunts these deuterium-heavy molecules into the duodenum (the gut) via pancreatic juice, effectively dumping them out of the systemic circulation. The Beta cells should produces close to 2L of bicarbonate a day to clear deuterium assuming the beta cell pancreatic circadian clocks are operational
1. Transport from Mitochondria to Pancreas
Deuterium isn't transported as a free ion (D+) through the blood; that would be inefficient and potentially toxic. Instead, it moves via metabolic water and substrate cycling:
TCA Cycle Clearance: Mitochondria in cells throughout the body produce "metabolic water" as a byproduct of ATP production. If the mitochondria are struggling, they produce water with a higher deuterium-to-protium ratio.
The Glucose/Bicarbonate Shunt: Excess deuterium is often incorporated into organic molecules (like glucose or amino acids) or stays in the plasma as part of the bicarbonate buffer system (HCO−3).
The Pancreatic Pull: The pancreas has an incredibly high metabolic rate and blood flow. It "collects" these deuterated compounds from the circulation to synthesize digestive enzymes and bicarbonate. When the pancreas is functioning optimally, it shunts these deuterium-heavy molecules into the duodenum (the gut) via pancreatic juice, effectively dumping them out of the systemic circulation. The Beta cells should produces close to 2L of bicarbonate a day to clear deuterium assuming the beta cell pancreatic circadian clocks are operational