Renal histopathological analysis of 26 postmortem findings of patients with #COVID19 in China ca. 2020 from @Kidney_Int @AgnesFogo
#CoronaKidney #NephJC
๐๐ผ kidney-international.org/article/S0085-โฆ
The Novel Coronavirus 2019 Epidemic and Kidneys ca. 2020
โPostulatedโ mechanisms:
๐๐ผ Sepsis leading to cytokine storm syndrome
๐๐ผ Direct cellular injury due to the virus
#COVID19 #CoronaKidney #NephJC
๐๐ผ kidney-international.org/article/S0085-โฆ
Renal histopathological analysis of 26 postmortem findings of #COVID19 patients
๐ฌ RBC aggregates in proximal tubule cells & glomeruli
๐ฌ No fibrin or platelets
๐ฌ #COVID19 in podocytes and tubules
๐ฌ Severe endothelial injury
#CoronaKidney #NephJC
๐๐ผ kidney-international.org/article/S0085-โฆ
Collapsing Glomerulopathy in a Patient with #COVID19 ca. 2020 from @KIReports @renalpathdoc #CoronaKidney #NephJC
๐๐ผ kireports.org/article/S2468-โฆ
Collapsing glomerulopathy in a #COVID19 patient ca. 2020 from @Kidney_Int
Possible underlying mechanisms:
๐ Direct viral toxicity on tubular cells that also harbour ACE2
๐ Cytokine-mediated tubular damage
#CoronaKidney #Nephpearls
๐๐ผ kidney-international.org/article/S0085-โฆ
Endothelial cell infection and endotheliitis in #COVID19 ca. 2020 from @TheLancet #CoronaKidney
๐๐ผ marlin-prod.literatumonline.com/pb-assets/Lancโฆ
Tubuloreticular inclusions in #COVID19 related collapsing glomerulopathy ca. 2020 from @Kidney_Int #CoronaKidney
๐๐ผ kidney-international.org/article/S0085-โฆ
AKI Due to Collapsing Glomerulopathy Following #COVID19 Infection ca. 2020 from @KIReports #CoronaKidney
๐๐ผ kireports.org/article/S2468-โฆ
Collapsing glomerulopathy and #COVID19 ca. 2020 from @KIReports #CoronaKidney
๐๐ผ kireports.org/article/S2468-โฆ
Ultrastructural Evidence for Direct Renal Infection with #COVID19 ca. 2020 from @JASN_News #Nephpearls
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Newly Diagnosed Glomerulonephritis During #COVID19 Infection Undergoing Immunosuppression Therapy, a Case Report ca. 2020 #CoronaKidney
๐๐ผ pubmed.ncbi.nlm.nih.gov/32361703/?fromโฆ
Visualization ๐ฌof putative #COVID19 in kidney (Letter): Definite proof for presence of viral inclusions in cells requires an immunostaining w/ specific antibodies, whether in cultured cells or in tissue samples (ca. 2020) from @Kidney_Int #CoronaKidney
๐kidney-international.org/article/S0085-โฆ
Electron microscopic image of an isolate of #COVID19 seen here inside vacuoles (arrows). Note the dense membrane coat around the viral particles (ca. 2020) #CoronaKidney
๐๐ผ kidney-international.org/article/S0085-โฆ
Multivesicular bodies mimicking SARS-CoV-2 in patients without #COVID19 #CoronaKidney
๐๐ผ kidney-international.org/article/S0085-โฆ
Multivesicular bodies mimicking SARS-CoV-2 in patients without #COVID19 #CoronaKidney
๐๐ผ kidney-international.org/article/S0085-โฆ
Multiorgan and Renal Tropism of #COVID19 ca. 2020 from @NEJM
#CoronaKidney
H/T @VelezNephHepato
๐๐ผ nejm.org/doi/pdf/10.105โฆ
Electron Microscopic Investigations in #COVID19: Not all Crowns Are Coronas ca. 2020 from @Kidney_Int #CoronaKidney
H/T @kdjhaveri
๐๐ผ kidney-international.org/article/S0085-โฆ
Am I a Coronavirusโ๏ธ
#COVID19 #CoronaKidney
๐kidney-international.org/article/S0085-โฆ
Thrombotic Microangiopathy (TMA) in a patient with #COVID19 ca. 2020 from @Kidney_Int #CoronaKidney
๐๐ผ kidney-international.org/article/S0085-โฆ
Collapsing glomerulopathy following #COVID19 infection; possible relationship with APOL1 kidney risk alleles in African-Americans ca. 2020 #CoronaKidney
๐๐ผ immunopathol.com/PDF/ipp-6-e18.โฆ
Anti-GBM disease during the #COVID19 pandemic ca. 2020 from @Kidney_Int @Profcpusey @stephenmcadoo #Nephpearls
Thanks to @valerie_luyckx for sharing
๐๐ผ kidney-international.org/article/S0085-โฆ
Kidney Biopsy Findings in a Critically Ill #COVID19 Patient With Dialysis Dependent AKI: A Case Against โSARS-CoV-2 Nephropathyโ ca. 2020 from @KIReports #Nephpearls
Thanks to @valerie_luyckx for sharing
kireports.org/article/S2468-โฆ
#COVID19 Related Collapsing Glomerulopathy in a Kidney Transplant Recipient ca. 2020 from @AJKDonline #Nephpearls
Thanks to @kdjhaveri for sharing
ajkd.org/action/showPdfโฆ
#COVID19 Associated Kidney Injury: A Case Series of Kidney Biopsy Findings ca. 2020 from @JASN_News @renalmyeloma @kdjhaveri @VBijol @renalpathdoc #Nephpearls
๐๐ผ jasn.asnjournals.org/content/early/โฆ
SARS-Cov-2 virions or ubiquitous cell structures? Actual dilemma in #COVID19 era ca. 2020from @KIReports #CoronaKidney
๐๐ผ kireports.org/action/showPdfโฆ
Caution in Identifying Coronaviruses by Electron Microscopy ๐ฌ ca. 2020 from @JASN_News #Nephpearls #COVID19 #CoronaKidney
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Histopathologic and Ultrastructural Findings in Postmortem Kidney Biopsy Material in 12 Patients with AKI and #COVID19 ca. 2020 from @JASN_News @renalpathdoc @VBijol #Nephpearls #CoronaKidney
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Kidney Biopsy ๐ฌ findings in patients with #COVID19 ca. 2020 from @JASN_News @ColumbiaKidney #CoronaKidney #Nephpearls
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Kidney Biopsy ๐ฌ findings in patients with #COVID19 ca. 2020 from @JASN_News @ColumbiaKidney #CoronaKidney #Nephpearls #VisualAbstract
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Histopathologic and Ultrastructural Findings in Postmortem Kidney Biopsy Material in 12 Patients with AKI and #COVID19 ca. 2020 from @JASN_News #CoronaKidney #Nephpearls
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Postmortem Kidney Pathology Findings in Patients with #COVID19 ca. 2020 from @JASN_News #Nephpearls #CoronaKidney
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Histopathology and ultrastructural findings of fatal #COVID19 infections in Washington State: a case series ca. 2020 from @TheLancet #CoronaKidney
H/T @valerie_luyckx
๐๐ผ thelancet.com/journals/lanceโฆ
AKI and Collapsing Glomerulopathy Associated with #COVID19 and APOL1 High-Risk Genotype ca. 2020 from @JASN_News @Tiff_Caza @VelezNephHepato #CoronaKidney
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
Ultrastructural ๐ฌ Evidence for Direct Renal Infection with #COVID19 ca. 2020 from @JASN_News #CoronaKidney
๐๐ผ jasn.asnjournals.org/content/jnephrโฆ
COVAN is the new HIVAN:
the re-emergence of collapsing
glomerulopathy with #COVID19 ca. 2020 from @NatRevNeph @VelezNephHepato @Tiff_Caza @renalpathdoc #Nephpearls #CoronaKidney
๐๐ผ nature.com/articles/s4158โฆ
#COVID19 Causes a Specific Dysfunction of the Kidney Proximal Tubule ca. 2020 from @Kidney_Int #CoronaKidney #Nephpearls
๐๐ผ kidney-international.org/article/S0085-โฆ
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