Switching gears from covid-centric to #cancer, where there have been a flurry of important papers in the past week
1. "Our discovery of #lesionsegregation challenges longstanding assumptions of cancer evolution"
nature.com/articles/s4158… @nature
media.nature.com/original/magaz… @NatureNews
2. 2 new papers on clonal hematopoiesis, which is associated with increased risk of cancer and heart disease
nature.com/articles/s4158…
nature.com/articles/s4158…
3. 2 reports on using methylomes to detect or track cancer, one using plasma tDNA for brain tumors, the other urine and plasma for kidney cancer
@NatureMedicine
nature.com/articles/s4159…
nature.com/articles/s4159…
4. The use of patient-derived tumor cell clusters to understand the biology of an individual's cancer and rapidly test drug therapies @ScienceTM
stm.sciencemag.org/content/12/549…
5. Patient-specific genomic variant monitoring of cancer via plasma circulating tDNA
stm.sciencemag.org/content/12/548… @ScienceTM
6. The potential for fasting to favorably modulate the course of cancer in a randomized trial of 131 patients with breast cancer
nature.com/articles/s4146…
A nice update on use of extracellular RNA as a diagnostic for cancer and beyond
by @ElieDolgin @NatureOutlook
nature.com/articles/d4158…
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