Kulvinder Kaur MD Profile picture
Physician. Scientist. Patient HumanRights Advocate. President & CoFounder @OnCall4ON. Advisory Board @FSU_Canada. Team Humanity. Cupcake Connoisseur. My Ethos.

Sep 4, 2020, 11 tweets

1/ US & UK media finally reporting what we've known for months from published peer-reviewed research by leading scientists🌎: pre-existing cross-protective Tcell immunity & strong Tcell responses bode well for long-term #SARSCoV2 immunity, and #HerdImmunity may already be at hand

2/ US: "We may be closer to #HerdImmunity than previously thought. Are we fearing a ‘second wave’ which our immune systems already have well in hand? People show immunological response to #SARSCoV2 in their Tcells.. without necessarily showing antibodies."
spectator.us/closer-herd-im…

3/ "#HerdImmunity may be closer than thought—UK scientists say immunity likely far higher than what govt antibody tests shows b/c it doesn't account for Tcells. Top immunologists said infection-fighting Tcells are more durable/long-lasting than antibodies"
dailymail.co.uk/news/article-8…

4/🚨British Medical Assoc Journal @bmj_latest published Editorial highlighting imp of T-cell immunity “for epidemiological modelling of disease transmission & #HerdImmunity

“Current antibody tests fail to identify people who had mild #COVID19 infections”
bmj.com/content/370/bm…

5/🚨First @bmj_latest, now Journal of American Medical Assoc @JAMA_current: “Tcells another level of popn immunity against #COVID19

"Substantial data demonstrate:
pre-existing T-cell immunity to #SARSCoV2.. prior to pandemic.. & in those w/out infection”
jamanetwork.com/journals/jama/…

6/🚨Editorial in British Medical Assoc Journal @bmj_latest re pre-existing cross-protective Tcell immunity to #SARSCoV2 and herd immunity threshold.

“Immunologists.. agreed that Tcells could be a key factor.. preventing an epidemic rise in new infections”
bmj.com/content/370/bm…

7/Above @bmj_latest Editorial highlights “Swine flu déjà vu” & “lesson forgotten”

H1N1 Tcell “data forced change..at WHO/CDC from assumption before 2009 that most ppl ‘will have no immunity to virus’ to.. ‘vulnerability of population related..to level of pre-existing immunity’.”

8/UK: “These studies (on pre-existing cross-protective T-cell immunity) are of immense imp b/c they bring into question central assumption of global response to #COVID19—that b/c #SARSCoV2 is a novel coronavirus no one on Earth can have any immunity to it”
spectator.co.uk/article/the-gr…

9/Media in India now covering Tcell immunity. Silence still from #CdnMedia

"In Covid infection, Tcell immunity more long-lasting than antibodies.. Prior exposure to some other coronavirus(es) evoked cross-reacting Tcell immunity towards Covid coronavirus"
thehindu.com/opinion/op-ed/…

10/🚨Peer-reviewed study by German & Dutch scientists published this wk in Nature:
“Our data demonstrate pre-existing T-cell immunity induced by circulating human alpha & beta-HCoVs is present in young adults, but virtually absent in older adult subjects."
nature.com/articles/s4159…

11/Above German/Dutch Nature study: “To best of our knowledge—this is first time presence of cross-reactive Tcells to SARSCoV2 is compared in young & older adults. Our findings provide partial explanation for more severe clinical outcome of SARSCoV2 infection observed in elderly”

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