Antoine FLAHAULT Profile picture
Prof, MD, PhD, Université Paris Cité - Inserm (UMR 1137) and Honorary Prof. of the University of Geneva - Tweets express my views

Sep 22, 2020, 9 tweets

1/9 - “Kids may play a bigger role in the spread of #SARSCoV2 than initially suspected. Early suggestions that children are considerably less important drivers than adults are not confirmed by more recent research.” doi.org/10.1503/cmaj.1…

2/9 - “Kids older than 10 are just as likely to be infected or infect others with SARS-CoV-2. The picture is less clear when it comes to younger kids because of blind spots in the research.”

3/9 - “Children have been dramatically underrepresented in #COVID19 case counts because they are less likely than adults to show symptoms and therefore may escape detection. Seroprevalence studies can be equally misleading. Schools were closed when the studies were done.”

4/9 - “Kids may have some biological protection against #SARSCoV2. The virus uses angiotensin-converting enzyme 2 (ACE2) receptors in the nasal mucosa as a doorway into the cells, and studies have found that young children have a lower density of those receptors.”

5/9 - “Yet, nobody knows if kids’ poor adherence to physical distancing and other precautions cancel out any biological advantage.”

6/9 -“An outbreak at an overnight youth camp found that younger children were at least as likely as older attendees to become infected with #SARSCoV2.Young kids with #COVID19 have similar viral loads to older kids and adults,although it is unclear if they are equally infectious.”

7/9 - “An influential rapid review published in April found a lack of evidence to support closing schools. However, some media mistook that finding as proof that school closures don’t work. They mixed up a lack of evidence with a lack of effectiveness.”

8/9 -“Denmark shown that reopening schools can be safe, provided that local transm is low and appropr measures are in place (reducd class sizes and well-ventilatd classrooms).Reopening without such meas. cld be associatd with a higher number of school outbrks, as seen in Israel.”

9/9 - “There will be outbreaks in schools, so the more we keep class bubbles relatively small and isolated from each other, the better we will be able to shut down individual classes instead of having to close entire schools.”

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