Therapies for #NAFLD by @klkrok
@AmCollegeGastro #ACG2021 #LiverTwitter #Liver #fattyliver #GITwitter
A case!
⚠️11% of patients with incidentally discovered steatosis may be at risk for advanced hepatic fibrosis!
Don't ignore patients with incidentally found steatosis!
Determining degree of fibrosis: NAFLD fibrosis score and FIB-4 are easy, noninvasive, and useful!
Treatment of #NAFLD
Note metformin is ABSENT, since it's NOT an effective therapy for NAFLD!
WEIGHT LOSS is 🔑
7-10% of body weight loss ▶️ 50% regression of liver scarring/fibrosis
> 10% ▶️ >80% regression!!!!
Vitamin D may protect against hepatic inflammation
Vitamin E is recommended in patients with biopsy proven #NASH, except in patients with diabetes.
✅GLP-1 analogues
✅Statins should be given to ALL patients with NASH/NAFLD. They are SAFE even if elevated liver chemistries!!!
✅Coffee! ☕️ ☕️ ☕️ ☕️ ☕️ ☕️ ☕️ ☕️
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