John Damianos, M.D. Profile picture
@MayoClinicGIHep Gastroenterology & Hepatology Fellow. Yale Internal Medicine, Dartmouth Med. 🦠Microbiome, brain-gut axis, diet, IBS, IBD, motility, #MedEd🇬🇷

Oct 23, 2022, 15 tweets

🎯 Goals in management of inflammatory bowel disease with @MLongMD

#MedTwitter #GITwitter #IBD #ACG2022

Only a minority of Crohn disease patients have an indolent course. The majority have PROGRESSIVE disease. We need to identify these patients and treat them in the window of opportunity.

In determining treatment, consider: symptoms, endoscopy, and prognosis

Ulcerative colitis severity definitions

🔑Symptoms and inflammation do NOT correlate well!

New goals

How to achieve better outcomes in #IBD

⏰ Timing matters
-earlier TNF use in CD protects against steroids and surgery
-early intervention ⬇️ disease-related complications

🎯Treat-to-target

Biomarker-based TTG may improve outcomes

📊Active monitoring of disease improves outcomes

Why is active monitoring important? Even "silent" #IBD portends complications

🔑Not all symptoms in #IBD are due to inflammation

Relevant shameless plug for our review on #IBS symptoms in #IBD!

@MLongMD summary on new 🎯s in #IBD

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