Daniel Gewolb, MD Profile picture
2nd year Neuroradiology Fellow @PennRadiology l Former resident @AlbanyMedRadRes l SGU ’18 l Daily Educational Cases #RadRes #Neurorad #RadEd

May 23, 2023, 10 tweets

Interesting case in this patient with acute right-sided weakness

#neurorad #neurotwitter #meded #Neurosurgery #Neurology @TheASNR @RSNA #medtwitter

Can you determine the diagnosis off the CT?

▶️Initial non-con CT shows a 3cm hyperdense lobulated extra-axial mass in the expected region of the left MCA bifurcation, consistent with a giant aneurysm. There are associated peripheral calcifications

▶️ What is the cause of the surrounding hypodensity?

What is the cause for the surrounding hypodensity?

▶️Mass effect and/leakage from the aneurysm induces vasogenic edema which moves easily through the white matter and relatively spares the more dense gray matter.

▶️However, we also see more subtle hypodensity of the lateral temporal lobe cortex, suspicious for acute ischemia

▶️CTA shows filling of the partially thrombosed aneurysm

▶️CT perfusion shows reduced CBF and corresponding elevated Tmax within the left MCA territory

▶️I am not sure if the stroke is due to thromboembolism from intraaneurysmal thrombus or if it’s 2/2 altered flow kinetics given the large size 🤷🏻‍♂️ (no occlusion was seen)

▶️Thoughts welcome 🙏

▶️MR shows the hypointense aneurysm on T2 with mixed iso and hyperintensity on T1

▶️ADC nicely delineates the areas of shine through from vasogenic edema and low ADC value from cytotoxic edema 2/2 infarct

▶️The aneurysm was treated with flow diversion using a pipeline shield rather than coiling due to a wide neck.

▶️Follow up, shows persistent filling of the sac despite stent placement

Learning points:

💡 Most intracranial aneurysms are asymptomatic

💡 Complications include rupture and rarely stroke

💡 When you see vasogenic edema around an aneurysm you must worry about impending rupture/leaking (as shown below, 24 hours apart in a different patient)

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