Daniel Gewolb, MD Profile picture
May 23, 2023 10 tweets 6 min read Read on X
Interesting case in this patient with acute right-sided weakness

#neurorad #neurotwitter #meded #Neurosurgery #Neurology @TheASNR @RSNA #medtwitter ImageImageImageImage
Can you determine the diagnosis off the CT?
▶️Initial non-con CT shows a 3cm hyperdense lobulated extra-axial mass in the expected region of the left MCA bifurcation, consistent with a giant aneurysm. There are associated peripheral calcifications

▶️ What is the cause of the surrounding hypodensity?
What is the cause for the surrounding hypodensity?
▶️Mass effect and/leakage from the aneurysm induces vasogenic edema which moves easily through the white matter and relatively spares the more dense gray matter.

▶️However, we also see more subtle hypodensity of the lateral temporal lobe cortex, suspicious for acute ischemia ImageImageImage
▶️CTA shows filling of the partially thrombosed aneurysm

▶️CT perfusion shows reduced CBF and corresponding elevated Tmax within the left MCA territory ImageImage
▶️I am not sure if the stroke is due to thromboembolism from intraaneurysmal thrombus or if it’s 2/2 altered flow kinetics given the large size 🤷🏻‍♂️ (no occlusion was seen)

▶️Thoughts welcome 🙏
▶️MR shows the hypointense aneurysm on T2 with mixed iso and hyperintensity on T1

▶️ADC nicely delineates the areas of shine through from vasogenic edema and low ADC value from cytotoxic edema 2/2 infarct ImageImageImageImage
▶️The aneurysm was treated with flow diversion using a pipeline shield rather than coiling due to a wide neck.

▶️Follow up, shows persistent filling of the sac despite stent placement ImageImage
Learning points:

💡 Most intracranial aneurysms are asymptomatic

💡 Complications include rupture and rarely stroke

💡 When you see vasogenic edema around an aneurysm you must worry about impending rupture/leaking (as shown below, 24 hours apart in a different patient) ImageImage

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More from @daniel_gewolb

Dec 10, 2024
Back from Belize! 🇧🇿

🔷What is the most likely diagnosis in this 25 y/o F w/ a band-like scalp lesion and local alopecia?

#Medicine #radres #futureradres #ENT #Rheum #Neurology #neurosurgery #Ophthalmology #FOAMed Image
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Answer: Linear Scleroderma aka Scleroderma en coup de sabre

🔷Linear scleroderma is a focal form of scleroderma resulting in atrophy and alopecia of the frontal or frontoparietal scalp

🔷Atrophy involves the subjacent skull +/- underlying brain parenchyma (as seen in this case)
🔷Brain parenchymal abnormalities may have calcifications or micro-hemorrhage

🔷Linear scleroderma is associated w/ progressive facial hemiatrophy (Parry-Romberg syndrome) Image
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Read 4 tweets
Nov 27, 2024
⭐️ What is the most likely diagnosis in this asymptomatic patient? What would your recommendation be if any?

#ENT @ASHNRSociety #Medicine #radres #futureradres #Neurology #Neurosurgery #ophthalmology #FOAMed Image
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Answer: Benign-appearing notochordal lesion (formally ecchordosis physaliphora, EP)

💡 If no remote priors for comparison, recommend 6 month follow up which can be extended if unchanged at that time
🔷Pathologic nomenclature was revised from EP to benign notochordal cell tumor (BNCT)

🔷Notochordal remnants are a pathologic spectrum ranging from benign (EP/BNCT), indolent, intermediate, & aggressive chordomas
Read 7 tweets
Nov 24, 2024
⭐️What is the most likely diagnosis in this 40 y/o M presenting w/ 10 days of L neck/throat/ear pain, worsened by neck palpation and head turning?

🔷PMH: None
🔷ESR/CRP: Mildly ⬆️

#Medicine #Neurology #neurosurgery #ENT #radres #futureradres #FOAMed @ASHNRSociety Image
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⭐️ Answer: Transient Perivascular Inflammation of the Carotid Artery (Carotidynia or Fay syndrome)
🔷Pathology: Unknown inflammatory process of the carotid wall

🔷Epidemiology:
▶️Young and middle age adults
▶️No gender predilection
Read 7 tweets
Nov 22, 2024
What is the most likely diagnosis in this 30 y/o M presenting with seizures, fever & headache?

🔷CSF x2:
Worsening neutrophilic pleocytosis despite Abx
Negative infectious studies
No malignancy on cyto/flow
OCBs +

🔷CT CAP: normal
#neurology #medicine #radres @AlbanyMedRadRes Image
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Additional image 👇
#futureradres #Neurosurgery #FOAMed Image
Answer: FUEL “FLAIR-variable unilateral enhancement of the leptomeninges” in MOGAD

🔷MOG antibody-associated disease (MOG-AAD)

Path: MOG-AAD is an autoimmune inflammatory demyelinating disease targeting oligodendrocytes
Read 12 tweets
Nov 19, 2024
⭐️ Classic case: 45 y/o Female presents w/ intermittent R pulsatile tinnitus for 1-2 years, what’s the most likely diagnosis?

#meded #medicine #ENT #Neurology #radres #futureradres #neurosurgery @ASHNRSociety Image
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Answer: Glomus Tympanicum Paraganglioma

🔷PATHOLOGY: Benign tumor arising from glomus bodies along the inferior tympanic nerve (Jacobson nerve)
🔷CLINICAL:
▶️Vascular retrotympanic mass
▶️Pulsatile tinnitus
▶️Female predominance (~3:1)
▶️Generally middle age at diagnosis
Read 8 tweets
Nov 15, 2024
60 y/o F presents w/ several months of confusion, word finding difficulty & gait dysfunction

🔷What is your best guess and differential?

🔷More images in 🧵
#MedEd #radiology #Neurology #radres #neurosurgery #medicine #ENT #Ophthalmology #futureradres Image
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🔷More images 👇 Image
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Answer: Glioblastoma on pathology

🔷Imaging: Tumor, high grade glioma vs lymphoma

🔷This case of glioblastoma is not classic and has overlapping features with lymphoma
Read 11 tweets

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