Organismic agency for desert after a very productive lunch with my fellow @PTPBio editors. #ISHPSSB19
@PTPBio Hugh Desmond: agential explanation – valid? indispensable? or just a far-fetched metaphor? #ISHPSSB19
Denis Walsh: agency – future-determining, teleological, and normative. #ISHPSSB19
Denis Walsh: “an agent is a purposive system embedded in a ‘landscape’ of affordances.” #ISHPSSB19
Denis Walsh: agency needed for any substantive theory of the organism based on closure, autonomy, and coupling. #ISHPSSB19
Denis Walsh: agency manifests itself in organismic contributions to adaptive evolution (plasticity, niche construction etc) #ISHPSSB19
Denis Walsh: causal explanations capture counterfactual dependencies of effects on causes; teleological explanations capture counterfactual dependencies of means on the goals to achieve them. #ISHPSSB19
Tim Lewens: agential self-organisation and selection for adaptation/adaptedness: a middle way. #ISHPSSB19
Tim Lewens: population-level factors (e.g. population size) clearly affect adaptive evolution in addition to the behaviour of individual agents. #ISHPSSB19
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@balazskegl @drmichaellevin @ThouArtThat I don't know what @drmichaellevin posted above since he blocked me. But just to make sure: we are *not* part of the same family. And the differences between our philosophies are fundamental, not "minuscule." Neither is @drmichaellevin a revolutionary. Indeed, he is a reactionary.
@balazskegl @drmichaellevin @ThouArtThat I explain why @drmichaellevin's "philosophy" is vacuous, just a PR stunt, here: . TAME is an attempt at disguising that his approach is, in fact, utterly reductionist, the culmination of modernist thinking, not the beginning of a metamodern science.johannesjaeger.eu/blog/why-tame-…
@balazskegl @drmichaellevin @ThouArtThat That's one difference between his work and that of @ThouArtThat and I, who are trying to do serious work, based on solid philosophy, which is aimed at *understanding* the world and our place in it, not to control and manipulate (i.e. engineer) everything.
I traveled to Paris to give my philosophy crash course for scientists () to a wonderful group of @lpiparis_ @FIREPhD students, as I do every year.
Contact me if you want to bring this course to your own institute! It's not only fun, but also useful...johannesjaeger.eu/philosophy.html
... allowing you to become a better researcher through philosophy. The course has an interactive, discussion-based format that is based on an online series of lecture which are freely available: .
It helps you reflect on your own scientific practice and world view using a (1) process-based, (2) perspectival-realist, and (3) deliberative approach to the philosophy of science. The course heavily focuses on students' own experiences, practices, and questions.
"I think assembly theory has lots of merit and potential, but this particular paper frames its argument in a way which is unfortunate and, frankly, more than just a bit misleading. My personal suspicion is that this has two reasons: (1) the authors hyped up their claims ...
... to get the paper published in a glam journal, plus (2) they also overestimate the reach and power of their model in ways which may be detrimental to its proper application and interpretation."
I submitted the paper knowing full well that @eLife usually restricts its scope to empirical work. The idea was to challenge that restriction, since (in my opinion) biology urgently needs a revival of serious conceptual efforts to prevent the descent of the field into pointless..
@eLife ... construction of large data sets that are increasingly costly to produce but yield diminishing returns in terms of insight and understanding into the workings and organization of living systems. Hence, no surprise when my work was deemed "out of scope." That's fair enough.
The current #COVID19 media coverage around me seems to agree on three things: (1) there is nothing we can do against #omicron, (2) this variant is mild & the wave will be over soon, (3) we're soon going "endemic," to "live with the virus," & back to normality. /1
There seems to be very little push-back against this narrative, which is something that really surprises me. But worse than that: it does *not* bode well for the next pandemic (whether the next #COVID19 variant or something altogether more worrisome). /2
Re (1): we can't do anything & #ZeroCovid was never an option.
Well, we never really tried. Those few countries that did were isolated (either geographically or surrounded by countries who didn't implement any low-incidence measures). /3
Our second paper on dynamical modularity, "Dynamical Modules in Metabolism, Cell and Developmental Biology" by @NickMonk14 & myself is now available as a preprint: osf.io/rydbn via @OSFramework /1
It complements our earlier evolutionary perspective on the subject (osf.io/vfz4t) with its more regulation-based approach and a long list of practical examples that illustrate our novel conceptual framework for the dynamical decomposition of complex systems. /2
Just like our earlier paper, the argument starts with the following observation: modular phenotypic traits imply that the underlying regulatory processes—the epigenotype of the organism—must be dissociable as well. How to decompose them, however, is not a trivial task. /3