Thread by @TheLancet

Just published: A new 5-paper Series, with contributions from @genome_gov, focuses on the exciting and maturing area of #genomicmedicine, encompassing the use of individuals’ genetic information to guide clinical treatment hubs.ly/H0k35bk0

@genome_gov @NIH @GenomicsEngland "As this Series emphasises, #genomics is now an essential part of high-quality patient care in rare disease, cancer & those areas of mainstream medicine where pharmacogenomics & the need for precision diagnostics is growing." Comment by M Caulfield et al hubs.ly/H0k6Q-M0

@genome_gov @NIH @GenomicsEngland @QMUL @QMULWHRI @GreatOrmondSt "I see genomics as providing another way of assessing risk and enabling better management of our patients"

Profile: Teri Manolio, Director of Genomic Medicine at @genome_gov & lead author of our new Series on #genomicmedicine hubs.ly/H0k7Pd00

@genome_gov @NIH @GenomicsEngland @QMUL @QMULWHRI @GreatOrmondSt #GenomicMedicine Series: Teri Manolio et al describe major types & measurement tools of genomic variation of current clinical importance, approaches to interpreting genomic sequences & key barriers in using #genomic information in routine clinical practice hubs.ly/H0kdXQV0

@genome_gov @NIH @GenomicsEngland @QMUL @QMULWHRI @GreatOrmondSt #GenomicMedicine Series: Dan Roden et al review pharmacogenomics, the idea that genetic variation can be used to individualise drug therapy, and update on ongoing efforts to implement pharmacogenetics in clinical practice hubs.ly/H0kfZmW0

@genome_gov @NIH @GenomicsEngland @QMUL @QMULWHRI @GreatOrmondSt #GenomicMedicine Series: Anastasia Wise et al focus on the role of clinical #genomic sequencing (exome and genome) in aiding patients with conditions that are undiagnosed even after extensive clinical evaluation and testing hubs.ly/H0klHyv0

@genome_gov @NIH @GenomicsEngland @QMUL @QMULWHRI @GreatOrmondSt #GenomicMedicine Series: G Ginsburg et al discuss family health history, which combined with genome sequence, lifestyle & environmental data, can provide robust means to identify individuals at risk & clear actions to reduce risk of common complex diseases hubs.ly/H0kp0CL0