Thread by @DrSGraff

Important research on supplements during chemotherapy #bcsm /1

https://twitter.com/MDRoeland/status/1208093270850637826

There were indications that use of any antioxidant supplement (vitamins A, C, and E; carotenoids; coenzyme Q10) both before and during treatment was associated with an increased hazard of recurrence (adjusted hazard ratio [adjHR], 1.41; 95% CI, 0.98 to 2.04; P = .06) /2

Relationships with individual antioxidants were weaker perhaps because of small numbers. For nonantioxidants, vitamin B12 use both before and during chemotherapy was significantly associated with poorer disease-free survival (adjHR, 1.83; 95% CI, 1.15 to 2.92; P < .01)... /3

....& overall survival (adjHR, 2.04; 95% CI, 1.22 to 3.40; P < .01). Use of iron during chemotherapy was significantly associated with recurrence (adjHR, 1.79; 95% CI, 1.20 to 2.67; P < .01) as was use both before & during treatment (adjHR, 1.91; 95% CI, 0.98 to 3.70; P = .06)/4

We need to carefully discuss supplements during #breastcancer treatment! #bcsm @OncoAlert /5 end