Discover and read the best of Twitter Threads about #breastcancer

Most recents (24)

Do you know what you're eating?

Probably not.

Here are 10 mind-blowing facts about the
American food system. 🧵
27 US states legally feed plastic to livestock.

The 'food waste' effort, championed by the nation's largest pork producer @SmithfieldFoods, allows old food and garbage (including packaging) to be ground directly into livestock feed. Image
Read 20 tweets
🍒 Put 'Em on the Glass 🍒

An interesting article about the SARS2 spike binding to Estrogen Receptor-α (ERα) and causing severe coagulopathy in Acute Covid and COVID 💉.

This leads to a question about spike ERα binding and cancer. >…
These researchers designed a spike protein with point mutations which eliminate the ERα binding, improving AE outcomes in the vaxxed.

(Because improvements are urgently needed in a 💉 with "extremely rare effects" in a "minority" of patients.)🙄 #ShibbolethsOfTheDamned > Image
Read 11 tweets
@TumorBoardTues 1/15 #TumorBoardTuesday #BCSM #BreastCancer #OncTwitter @drteplinsky

🎯45 yo premenopausal 👩‍🦰
❌relevant medical history.
FHx: Mom 👩‍🦳 with breast cancer at 48y
Screening mammogram normal for the last few years.
Now with microcalcifications 📏3mm in the UOQ of the R breast.
@TumorBoardTues @drteplinsky 2/15 #TumorBoardTuesday #BreastCancer #OncTwitter @MPishvaian @JohnEbbenMDPhD

👩‍🦰Underwent a biopsy
🔬Surgical pathology: Atypical ductal hyperplasia
✂️Underwent a lumpectomy confirming diagnosis and no additional findings

🤔Which of the following would you recommend for her?
Read 19 tweets
🌻This Tuesday 05.16.23 at 8pm ET @drteplinsky @prarthnavb join #TumorBoardTuesday to take us through using baby Tam for high risk lesions & in #BreastCancer

💬Join us!

🧠While we finalize the case, collect FREE #CME

👉🏽 2023👈🏼#OncTwitter #BCSM Join us for a #TumorBoardTu...
@drteplinsky @prarthnavb @MPishvaian @JohnEbbenMDPhD @Dr_RShatsky @hmcarthur @DrSGraff @DrTimothyErick @MdVarvaras @sardesai_sagar @ZainabFatima100 @AnupamaN20 #TumorBoardTuesday

What to recommend for your patients who are high risk #BreastCancer?

👉🏽Join @drteplinsky @prarthnavb Tues 05/16/23 at 8PM ET

📊Respond to polls
Weigh in & bring citations🧾
Retweet & tag your colleagues
🏆Earn FREE CME: Join us for a #TumorBoardTu...

B4⃣ the #BreastCancer case, help us guide the discussion and tell us your connection to🩺 cases like these.

🧐Where you are in your 🩺 journey?

Read 5 tweets
1/6 #TumorBoardTuesday

🔬🧬@PGrivasMDPhD @rafee_talukder discussed variant histology #urothelialcarcinoma & cis-ineligible dz

➡️Thursday Case wrap up 🎀

🆓 #CME: answer 2 quick ❓
CME eval🔗: Image
2/6 #TumorBoardTuesday
Thurs Case🎀
✅Variant hist UC changes tx
⬇️resp to plat 👉surg first, clin trial
✅Cis inelig mUC- acc approval: Enfortumab Vedotin + pembro 1L
✅Trials: 1L SG + IO, others

📚Here’s @PGrivasMDPhD @rafee_talukder’s thread…
@PGrivasMDPhD @rafee_talukder 3/6 #TumorBoardTuesday
Thursday Case🎀
🎞️ TBT in a video

Here’s the highlight reel:
Dr. Talukder & Grivas talk about:
🔹new approaches for cis ineligible disease
🔹variant histology
🙌 what to look forward to at #ASCO2023.

Check out the next tweet for the Director’s 🎬 cut!
Read 10 tweets
@TumorBoardTues @JenniferLitton @marijasullivan @MPishvaian @MDAndersonNews @BreastCaupdates @BRCAUmbrella @hoperugo @Dr_RShatsky 2/5 #TumorBoardTuesday
✅ 🧬test 🗝️! Biomarkers 👉 best tx
✅ OlympiA: OS & IDFS⬆️w Olaparib- gBRCAm
✅ MonarchE: IDFS⬆️ w abema +ET- HR+
✅ Fertility pres & interrupting adj tx (if desired) for pregnancy
📚@JenniferLitton @marijasullivan’s thread…
@TumorBoardTues @JenniferLitton @marijasullivan @MPishvaian @MDAndersonNews @BreastCaupdates @BRCAUmbrella @hoperugo @Dr_RShatsky 3/5 #TumorBoardTuesday
Thursday Case🎀

🎥 TBT in a video
@marijasullivan summarizes adj tx based on biomarkers. How to approach pts w gBRCA1/2m & HR+? Need more data!

🔹gBRCAm👉 Olaparib x 1y
🔹 HR+👉 Abemaciclib + ET x 2y -> ET; data expected on other CDK4/6i soon (ribociclib)
@TumorBoardTues @JenniferLitton @marijasullivan @MPishvaian @MDAndersonNews @BreastCaupdates @BRCAUmbrella @hoperugo @Dr_RShatsky 4/5 #TumorBoardTuesday
📷 TBT in an image

In pts who desire pregnancy, data that adj tx can be interrupted & later resumed safely- waiting on long-term follow up @AnnPartridgeMD.

✅Pregnancy outcomes after #BreastCancer NOT worse. Fertility pres strat BEFORE tx 🗝️ if desired. Image
Read 8 tweets
@TumorBoardTues @JenniferLitton 1/18 #TumorBoardTuesday #BreastCancer #OncTwitter

32 yo 👩🏽
4 months post-partum
FHx paternal uncle with #PanCan
🔬Bx: L breast mass - IDC, G3, ER 50%, PR 30%, HER2 0, Ki67 30%
Clinically node+; FNA confirms LN involvement
🚫 e/o metastatic dz

🤔Do all EXCEPT?
@TumorBoardTues @JenniferLitton 2/18 #TumorBoardTuesday #BCSM @JenniferLitton

🧬 testing returns with BRCA2 path variant
✂️ L mastectomy and ALND
Right risk ⬇️ mastectomy
Found to have 8+/15 LNs
Undergoes adjuvant AC/T

🤔After referring to ☢️ XRT, you discuss which of these treatments?

ET= AI+OS vs Tamoxifen
Read 23 tweets
@TumorBoardTues @drsarahsam 1/24 #TumorBoardTuesday #BreastCancer #OncTwitter
54yo 👩🏻 post-menopausal
FH: aunt with late-onset BC
Germline genetic testing: negative

🔪Dec ‘10 Left lumpectomy + SLNB:
left IDC G2
ER 95%
PgR 10%
HER2-neg (IHC 1+)
Ki67 35%
stage pT2 (25 mm) pN0
Oncotype 32
@TumorBoardTues @drsarahsam 2/24 #TumorBoardTuesday #BCSM

☢️Jan ‘11: TC x 4 ➡️ XRT
Treatment well tolerated, apart from alopecia, G2 fatigue

Summer ‘11 – started letrozole
🔀 Fall ‘11 – switch to exemestane due to G3 arthralgias ➡️ improvement of symptoms

2016 completed 5 years of Aromatase Inhibitor
@TumorBoardTues @drsarahsam 3/24 #TumorBoardTuesday #BCSM

Apr ‘21 – Mild abdo discomfort
🩻CT CAP scan:
liver: 5 lesions, max 15 mm
bone: spine & ribs
enlarged mediastinal lymph nodes
🩸: G1 anemia, normal LFTs, no other abnormality

🔬US-guided liver biopsy:
IDC, grade 2, ER 90%, PR 0%, HER2-0, Ki67 25%
Read 26 tweets
@TumorBoardTues @ShrutiPatelMD @NarjustFlorezMD @LungAssociation @DrSteveMartin @FawziAbuRous @esinghimd @RenoHemonc @HemOncFellows 2/5 #TumorBoardTuesday
Thurs Case🎀
✅Biomarker - sq cell #LC, chemoIO is the SOC
✅Pembro, cemi, ipi/nivo approved in 1L squamous cell lung cancer—must be paired with chemo if PD-L1 TPS < 50%
✅ irAEs can be very serious- early, multi-D mgmt is 🗝️

@TumorBoardTues @ShrutiPatelMD @NarjustFlorezMD @LungAssociation @DrSteveMartin @FawziAbuRous @esinghimd @RenoHemonc @HemOncFellows 3/5 #TumorBoardTuesday
Thurs Case🎀

📽️TBT video wrap up:

IO has fundamentally changed 🫁 cancer tx.
Choosing the right strategy in squamous cell lung ca largely based on PD-L1 status; we’re hoping for more, & better, biomarkers in the future.
@TumorBoardTues @ShrutiPatelMD @NarjustFlorezMD @LungAssociation @DrSteveMartin @FawziAbuRous @esinghimd @RenoHemonc @HemOncFellows 4/5 #TumorBoardTuesday
Thurs Case🎀

📷TBT in an image:

Check out this algo to help select IO vs chemoIO strat in #squamouscell #lcsm lung cancer 1L setting.
No head-to-head 👊data to define clear winner, but pembro, cemiplimab, and ipi/nivo approved based on OS benefit. Image
Read 18 tweets
1/22 #TumorBoardTuesday #OncTwitter

60yo 👩🏻‍
ER+/PR-/HER2 low met #BreastCancer
Since 2016: 3 lines of endocrine therapy including AI+CDK 4/6 inhibitor ➡️ Fulvestrant ➡️ Everolimus+exemestane
No actionable mutation

🤨 What would be your first chemotherapy choice:
2/22 #TumorBoardTuesday @MPishvaian @JohnEbbenMDPhD #BreastCancer #BCSM

2021*: Started on capecitabine for 8 months until POD
2022: Switched to paclitaxel for 5 months ➡️ POD in the liver and pleura

🤨 What would be your next step?
3/22 #TumorBoardTuesday
👩🏻‍🏫Mini tweetorial 1

📌What is HER2-low?

🔸Traditionally HER2-positive and HER2-negative were separate entities
🔸NOW, HER2-low is a separate entity 👉🏽 1+ or 2+ on IHC and ISH negative‼️

📚@PTarantinoMD @curijoey @stolaney1…
Read 24 tweets
“Women are under such pressure to look a certain way that they must undergo this pain after a traumatic surgery. That’s why I decided to make crocheted or knitted prostheses," says⁠
Jayashree Ratan.⁠

#HeroesOfHumanity #WorldCancerDay #Kindness #WomenForWomen #Healthcare Image
Jayashree Ratan creates crocheted #prostheses for #breastcancer survivors.⁠

Made from 100 per cent mercerised cotton yarn, these prostheses are soft on the skin and do not cause allergies.
While each can be used for nearly two years, these washable hands fit well into the mastectomy bra.⁠

“We never knew we would touch so many lives by spending just a few hours on each product. That is our biggest reward,” says Jayashree.⁠
Read 4 tweets
Today is #WorldCancerDay

Few diseases reflect global inequities as starkly as #BreastCancer and #CervicalCancer.

Nearly 8⃣0⃣% of deaths from breast and cervical cancer occur in low- and middle-income countries.

#CloseTheCareGap in #cancer ⬇️
On #WorldCancerDay, here are some ways to reduce ↘️ your #cancer risk:

🚭 Don't use tobacco
🏊‍♂️ Exercise regularly
🍅 Eat healthy foods
☀️ Avoid strong sunlight for prolonged periods
🥃 Drink less alcohol

📌 Icons illustrating the text below.   Reduce your risk of can
Today is #WorldCancerDay

These are the 5⃣ most common types of #cancer:
🔸 breast
🔸 lung
🔸 colorectal
🔸 stomach
🔸 prostate

📌 Icons depicting the most common cancers types: - Breast - Lu
Read 13 tweets
We have insights! Learn about how insurance companies have gamed the medical coding process to deny #breastcancer patients access to modern #reconstruction treatments @DavidArmstrongX @propublica @PatrickMRucker @mayatmiller

This petition explains:…
Read 6 tweets
Breast Conservation | The importance of self breast examination!

“Self berast examination allows you to evaluate your own breast, it teaches you to examine your breast, understand the lumps and bumps in your breasts.”

@TataMemorial | @CancerGridIndia | @nitaSnair

Listen to Dr. Nita S Nair, Surgical oncologist and Professor in breast oncology at the Tata Memorial Centre, Mumbai. give us valuable insights into Breast Conservation.

#Cancer #TMCNCGNavyaWay #BreastCancer #BreastConservation
TMC NCG Navya ensures that all cancer patients can afford treatment recommendations from expert oncologists through our strong alliances with experts, nonprofits, and industry.

#CancerCare #HealthIsWealth #BreastExamination
Read 4 tweets
@TumorBoardTues @jane_meisel @MPishvaian @JohnEbbenMDPhD 1/17 #TumorBoardTuesday #BreastCancer #OncTwitter @JasmineSukumar @DrGattiMays
👩🏽 65 yo post-menopausal
🔺Triple-neg MBC, germline BRCA1 mut+, PD-L1 neg
👉On carbo/gem for 6 cycles

🩻NOW: Scans show progression in liver

🤨What 2L treatment do you recommend?
@TumorBoardTues @jane_meisel @MPishvaian @JohnEbbenMDPhD @JasmineSukumar @DrGattiMays 2/17 #TumorBoardTuesday #bcsm

🤨 Poll: What percent of all people diagnosed with #BreastCancer carry a germline BRCA 1 and/or 2 mutation?

🤔Are there features that might make you more likely to suspect a patient is a mutation carrier?

@StoverLab @sardesai_sagar @OncoAlert
@TumorBoardTues @jane_meisel @MPishvaian @JohnEbbenMDPhD @JasmineSukumar @DrGattiMays @StoverLab @sardesai_sagar @OncoAlert 3/17 #TumorBoardTuesday
👩🏽‍🏫Mini tweetorial 1👩🏻‍🏫

📌BRCA1/2 mutation

🔸Repair double-stranded breaks thru HRR
🔸Unable to fix 🧬 when damaged ➡️ add’l muts ➡️ cancer
🔸~5% of #BreastCancer;⬆️w/ TNBC
🔸Assoc w/ 40-65% of BC dx in 🚺, ≤ 9% in 🚹
Read 22 tweets
For being the best #IPS probationer, Dr Darpan Ahluwalia was awarded the Prime Minister’s Baton and Home Ministry’s (MHA) revolver during the valedictory ceremony at the #NationalPoliceAcademy.
@AhluwaliaDarpan Image
An #MBBS degree holder from Government Medical College in Patiala, Ahluwalia also bagged the Vice President of India's trophy for exemplary conduct and Martyr K S Vyas trophy for internal security, public order and field craft and tactics.
On a mission to serve the public, Dr Ahluwalia also organises #breastcancer screening camps in #Punjab through the NGO Pink Link Campaign.
Read 4 tweets
Happy to announce our latest publication is online!
Huge effort from @ashkanshahbandi and co authors @Raegan2222 @SelinaSMJ_here @AshlynA_99 @LabMachado @Lorax_Bodyspray @Thesrao
#cancer #breastcancer #Immunotherapy #SABCS2022
a quick 🧵 tweetorial... Image
@ashkanshahbandi was interested in examining why some BC have residual disease after chemo Rx that persists. These tumors tend to be p53 wild type and tend to undergo cell cycle arrest/senescence rather than cell death #chemotherapy #residualdisease
Looking at immune regulatory pathways he found PD-L1 and CD80 were both highly induced in tumors from chemotherapy treated mice. By RNA, many checkpoints were induced in senescent human BC and mouse mammary tumors after chemo (Fig.1) Image
Read 20 tweets
Resources for those facing #breastcancer that I've personally used and found AMAZING. @ThanksCancer

A 🧵with links. Please share yours below.
Sharsheret - for people of all faiths to find financial and emotional support. I was matched with a social worker who sent a care pack and matched me with a mentor
Gilda's Club - I was incredibly overwhelmed at diagnosis but soon landed at my local chapter. Since I've utilized creative writing and art workshops, survivorship support, and even a free turkey at Thanksgiving
Read 9 tweets
🎉Immensely grateful and overwhelmingly joyful that my 1st first-author paper is out now in @BMCMedicine😁!!!🎉

This project started as my master’s thesis in @ImperialSPH with @VerenaZuber and @KTsilidis in the summer of 2020 😱!

Tweetorial 🧵⏬!

🎯Aim: We wanted to examine and rank all 34 blood and urine biochemical biomarkers in the @uk_biobank for possible #causal relationships with #breastcancer liability in women.

2/11 Study overview of our study...
🧮Methods: Since experimenting on biomarkers in human participants poses ethical and practical questions, we instead performed a method called Mendelian Randomisation (MR)🧬.

MR uses observational data👀 and an instrumental variable (IV) framework to infer causality.

Read 11 tweets
I've missed out on a lot of events this year due to #breastcancer, which means I've missed opportunities to engage with readers about my new book, #TheFacemaker. So, let me take a moment to tell you more about this book, which took me five years to research and write.👇 /1 Two books covers. On the le...
From the moment the first machine gun rang out over the Western Front, one thing was clear: Europe’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed.

Never before had the world faced such slaughter. /2 A black and white photo of ...
Stretcher-bearers could rarely step onto a battlefield without becoming a target. Their mortality rates were extraordinarily high. When Private W. Lugg picked up an injured man, it took him ten hours to travel 400 meters. Wheeled carts were mostly useless on blasted terrain. /3 A black and white photo of ...
Read 23 tweets
We are thrilled to share #Starfysh ⭐️ an auxiliary deep generative model for multi-modal analysis and integration of spatial transcriptomic (ST) datasets and histology images, and its application to heterogeneous #breastcancer tumors! 😃 1/ Image
Incredibly fortunate to have a passionate, collaborative & talented team that didn't slow down with all the challenges of the past few years 🙏: @SiyuHe7 @YinuoJin6, @AchilleNazaret @shi_lingting and a fruitful and ongoing collaboration with @GeorgePlitas and Sasha Rudensky. 2/
Using ST, we wanted to find out if our previously observed continuous phenotypic expansion of intratumoral immune states (…) could be explained by the #spatialdynamics of immune cells and exposure to different environmental signals and nutrient supply? 🧐 3/
Read 15 tweets
One of the most laughable things I’ve realized is people hosting Race for the Cure runs for #breastcancer but serving sugar laden donuts & cookies after. If they really want to help w/ cancer they should promote a lifestyle of zero sugar & fasting instead….but that’s not fun.
Another one is #Alzheimer fundraisers, again w/ alcoholic drinks & sugary food at the events, which totally contribute to dementia & poor brain cognition. But people want a photo dump of them “working” for a cause even if their efforts contradict good health. They need a party.
Because it’s not “really” about health, for if it were, they’d do their own research to see the food & drinks they’re serving actually contribute to these diseases. It’s about people being conditioned by Pharma & allopathic medicine & being clueless about how to heal from them.
Read 4 tweets
#WomensHealthcare needs serious attention, specifically patient comfort. There are procedures that the patient is given no anesthesia for that are down right medieval. For example, lets visit something called an endometrial biopsy, a procedure that detects uterine cancer… 1
1You will be asked to undress fully or from the waist down and put on a hospital gown.
2You will be told to empty your bladder before the procedure.
3You will lie on an exam table, with your feet and legs supported as for a pelvic exam…
4. Your healthcare provider will insert an instrument called a speculum into your vagina to spread the walls of the vagina apart to view the cervix.
5. Your provider will clean your cervix with an antiseptic solution….
Read 17 tweets

"Traición de la naturaleza"
(La lucha contra el cáncer de mama).

Un día, la naturaleza llevó la lucha por la supervivencia a los senos de la mujer. Atentó contra uno de los símbolos más sagrados que posee el ser humano, y golpeó, con saña, a nuestras madres.
Sin herramientas ni fármacos, otra vez la piedra del conocimiento debió tallarse rudimentariamente por siglos, para equilibrar la balanza. Indefenso, el hombre tuvo que cortar, y echó mano de los vestigios ancestrales de lo que hoy es la cirugía. Cortó, a destajo, cuerpo y alma.
La mastectomía apareció en el siglo II, d.C. siempre seguida del fuego ardiente que cauterizaba los vasos sangrantes; obvio no sería suficiente. 1200 años después empezaron a retirar los ganglios linfáticos axilares, tras entender que tendían a infestarse por el cáncer.
Read 28 tweets

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