Here’s what “World War Z” gets right: People panic. They get in their cars and run. They loot grocery stores. There are shortages of food, fuel, and medicines. #nCoV2019#coronavirus#coronavirusoutbreak
Here’s what “World War Z” gets wrong: No virus has a 12 second incubation period. It takes at least a minute for your blood to travel around the body, and it takes longer for your immune system to induce an immune response. #nCoV2019#coronavirus#coronavirusoutbreak
Deforestation (& climate change, overpopulation, etc) will lead us to come into contact with more zoonotic (i.e. animal) viruses. We’ll see more and more infectious disease outbreaks if these trends continue. #nCoV2019#coronavirus#coronavirusoutbreak
The bleeding/bruising makeup is beyond fake. The fixation on tracking down the infected monkey makes no sense. They’d already isolated the virus. They could just have injected the virus into other animals to make antiserum. #nCoV2019#coronavirus#coronavirusoutbreak
It would have taken months to make that much antiserum. Also, one monkey could not possibly have provided enough antiserum to save everyone. #nCoV2019#coronavirus#coronavirusoutbreak
@Columbia@Laurie_Garrett "Contagion" describes how different kinds of vaccines are made: inactivated/killed vaccines, live attenuated vaccines, and recombinant vaccines. The movie also accurately illustrates how contact tracing works. #nCoV2019#coronavirus#coronavirusoutbreak
@Columbia@Laurie_Garrett@cdc I’ve left out some other critiques that are a bit more in the weeds. These are the big ones. Key takehome message: Hollywood gets a lot of the science wrong. But it gets human behavior (fear, panic, rumormongering, opportunism) right. #nCoV2019#coronavirus#coronavirusoutbreak
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1/ H5N1 bird flu candidate vaccine viruses have been identified:
(jump to 1:33)
🔹2 are "well-matched" to H5N1 infecting dairy cattle
🔹but how "well-matched" are they really? this conclusion is based on ferret dataastho.org/education/hpai…
2/ 🔹Candidate vaccine viruses are used to make antigen (i.e. the target you want the immune system to see) for vaccines.
🔹Adjuvant has also been stockpiled.
🔹Adjuvants help strengthen the immune response to antigen in vaccines.
3/
🔹100s of thousands of doses of candidate antigen + adjuvant have been manufactured for use in clinical studies.
🔹2 safety/immunogenicity studies are being conducted.
🔹@ASPRgov is working with @US_FDA & industry to figure out a regulatory pathway for the use of these doses.
1/ Stemming the spread of H5N1 bird flu
🔹The federal government is ramping up testing of dairy cows
🔹Cows will now have to be tested before being transferred to another state
🔹H5N1 viral fragments detected in grocery store milk
🔹The risk to humans remains low at this time
2/ Remember PCR tests from COVID?
They can be positive even after you’ve recovered because they’re picking up dead virus.
Some PCR tests on pasteurized milk from grocery stores have come back positive for bird flu... but that could just be dead virus.
3/ Pasteurization has worked for over a hundred years to protect consumers from bacteria and viruses.
There’s no reason to think pasteurization won’t also work to kill the bird flu virus, but scientists are confirming that with testing anyway.