#covid19 infected per capita yesterday. In just a few days my country of birth Iceland went from 0 cases to 14, putting it on par with Italy. Most of these cases came indeed from one group on a ski-ing trip in Italy. Goes to show how quickly things can change with this outbreak.
N.b. The heading is in Icelandic and translated is roughly "Covid-19 infected people per million inhabitants"
Far out - just read that Iceland is up to 20 cases = 54 per million people - or nearly the same as China! Two "positives" so far: no-one seriously sick (and no deaths) and all cases so far from people that had been travelling (no in-community transmission so far).
The one "negative" is for the rest of the world: Iceland's small population etc has made the testing regime very effective and thorough. But, this could mean the real number in many bigger nations is a lot higher - just that they can't test "most travellers" etc like Iceland does
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How are mRNA vaccines made? A chemist’s perspective. TL;DR A DNA plasmid is used as template for the in vitro transcription of DNA to mRNA which is then packaged in a lipid nanoparticle. But it is a bit complicated than that. (image @AFox_Perththeconversation.com/australia-may-… ) 1/35
I am chemist with a life-long interest in viruses and self-assembly, working in the nanomedicine @ARCCoEBionano field for over 10 years. More recently, our group has been synthesising short RNA (unpublished work) with my colleague #ozchem@Fahrenbachus@UNSWScience 2/35
So when I heard first about mRNA vaccines back in April I was fascinated. Since then I have also become part of group mentioned in theconversation.com/australia-may-… article by @AFox_Perth that is arguing the case for local mRNA (and other RNA + DNA products) capabilities in Australia 3/35
1/21 Why would UV light be a really bad method for destroying the SARS-CoV-2 virus causing #COVID19 in your body or on your skin while it is a good method for disinfecting surfaces? TL;DR It destroys the viruses RNA. But also your DNA, which may lead to cancer.
2/21 I am a Chemistry Professor and I work in nanomedicine @UNSWScience@NanoMed_UNSW@ARCCoEBionano making amongst other things, self-assembled virus-like particles for cancer treatment. In my field, some "smart" particles can be triggered with light. cbns.org.au/photoswitchabl…
3/21 But in designing such nanoparticles one rule prevails - never ever create them to be triggered with UV light. Ideally only use lower energy visible or near-infrared light. The reason we all avoid UV light is that we know it damages DNA. And can lead to cancer.
1/18 A soap is a soap is a soap! I am still flabbergasted by your response to my Twitter thread about the #COVID19 Coronavirus, soap and supramolecular chemistry! I have been quite busy today but I in this thread I will try to provide answers to some of your questions:
2/18 A lot of the questions are basically about which soap is best? Some people ask if detergents are better/worse than soap? Let me start with the latter one. Basically, what people call a detergent and what is a soap seems to differ! To me as a chemists they are very similar.
3/18 The Wikipedia entry on detergents seems to delineate detergents from soap mainly by calling alkylbenzenesulfonates & similar chemicals detergents, whereas fatty acid salts are soaps. You find detergents mainly in things like laundry detergents. See en.wikipedia.org/wiki/Detergent
1/25 Part 1 - Why does soap work so well on the SARS-CoV-2, the coronavirus and indeed most viruses? Because it is a self-assembled nanoparticle in which the weakest link is the lipid (fatty) bilayer. A two part thread about soap, viruses and supramolecular chemistry #COVID19
2/25 The soap dissolves the fat membrane and the virus falls apart like a house of cards and "dies", or rather, we should say it becomes inactive as viruses aren’t really alive. Viruses can be active outside the body for hours, even days.
3/25 Disinfectants, or liquids, wipes, gels and creams containing alcohol (and soap) have a similar effects but are not really quite as good as normal soap. Apart from the alcohol and soap, the “antibacterial agents” in these products don't affect the virus structure much at all.