Thread by @aartisarwal

#SurvivingSepsis Campaign Guidelines on
the Management of Critically Ill Adults with #Covid_19

COVID-19 THERAPY

Link: journals.lww.com/ccmjournal/Abs…

#sepsis @CritCareMed @SCCM

#COVID_19 shows Cytokine Storm Syndrome reminiscent of secondary hemophagocytic lymphohistiocytosis

Resp failure in #COVID_19 WO #ARDS - Don't use routine steroids

Resp failure in #COVID_19 with #ARDS- may use steroids shorter course, lower doses

#sepsis @CritCareMed @SCCM

Use empiric abx in hypoxic resp failure + #COVID_19

Identifying bacterial co-infection or superinfection
in pts with #COVID_19 is challenging

Co-infection 5-18% in MERS, Staph aureus common, virulent. Secondary infection 11%, may be Gram-ve organism

#sepsis @CritCareMed @SCCM

#Covid_19 #sepsis treatment

Use acetamin/paracetamol for temp control

Do NOT use IVIG, conval plasma, lopinavir/ritonavir as routine

Remdesivir in clinical trials

Insufficient evidence for rIFN-β, tocilizumab, chloroquine or hydroxychloroquine

#sepsis @CritCareMed @SCCM