Be part of the Solution NOT part of the Problem. Ours is a partnership of 5 @theedgemalaysia MrDIY-IMARET-MERCY-MRA The EDGE flew in Tyvek Suits (ICU specs) and face-masks. Most distributed on 29-30/3/2020 theedgemarkets.com/content/news-e…
The TUDM plane next flew to Sarawak to deliver Tyvek Suits and masks to Bintulu, Miri, Sibu and Kuching. We are extremely grateful to @theedgemalaysia Mr DIY and our buddy from CVSKL who prefers to remain anonymous.
Our guys in IMARET, MERCY and MRA have been absolutely wonderful, totally selfless and flowing with love and friendship. The #COVID crisis has brought out the BEST from them ... but I am afraid the WORST in others as seen in #socialmedia@theedgemalaysia@DrAdhamBaba@DrDzul
Keberkesanan Vaksin Pfizer & Moderna Melawan Delta
Dikalangan 5.6 Juta Warga Emas 🇺🇸 >65 tahun
✅2.7 Juta Pfizer
✅2.9 Juta Modera
➡️148K Infeksi Breakthrough (2.6%)
➡️30K Masuk Hospital (20%)
➡️9.4K Masuk ICU (34%)
Tahap neutralizing antibodi lepas vaksinasi menentukan perlindungan-correlate of protection
➡️Neutralisasi boleh menjangka perlidungan drp sesuatu jenis vaksin.
➡️Model yg bakal diguna pakai utk mengawal trajektori pandemik dgn strategi vaksinasi nature.com/articles/s4159…
Amat besar jurang perbezaan titer antibodi (ab) antara vaksin mRNA & Sinovac.
Lepas 28 hari dos ke2
➡️Tahap ab PRNT50 mRNA 10X ganda
➡️Tahap ab PRNT90 mRNA 13X ganda
➡️Perbezaan 10-13X ganda tahap ab merupakan perbezaan yg besar didlm keberkesanan vaksin – Vaccine Efficacy (VE)
Keberkesanan vaksin (VE) ditentukan oleh antibodi & respon imun yg lain.
Universiti Hong Kong (HKU) menunjukkan vaksin mRNA lebih berkesan drp Sinovac kerana tahap ab yg 10X lebih tinggi.
Pengkaji HKU syorkan dos tambahan untuk penerima vaksin Sinovac
Wanita yg hamil & dijangkiti covid:
⬆️Covid teruk
⬆️Masuk ICU
⬆️Bantuan pernafasan
⬆️3X Mati dibandingkan dgn wanita covid yg tidak hamil
⬆️Sebab komobiditi hamil spt kencing manis, darah tinggi.
⬆️Keguguran
⬆️Kelahiran mati
⬆️Kelahiran pramatang
Vaksin Selamat
➡️2.4 juta wanita hamil terima pelbagai vaksin covid & selamat
➡️130K wanita terima vaksin mRNA & tiada kesan sampingan
➡️Ujian pra-klinikal tiada risiko kpd ibu atau kecacatan janin
➡️Kandungan Vaksin dah dinyah
➡️mRNA tak masuk nukleus
An oversimplification of the science 1. In first few days of illness viral loads (VL) r similar bet vaxxed & unvaxxed 2. NHS study only captured the early few days of symptomatic persons. 3. 90-97% mRNA and 70% AZ vaxxed are asymptomatic!
3. Though similar VL are they viable in vaxxed vs unvaxxed? 4. VL in vaxxed maybe rendered non-viable and/or less infectious. by neutralising antibodies 5. VL in unvaxxed are replication competent virus
6. PCR cannot differentiate between them threadreaderapp.com/thread/1424780…
7. We need a replication assay
8. After few days the VL drops faster in vaxxed below the contagious level. 9. Vaxxed persons overcome infxn faster-period of infectiousness shorter 10. Play safe scenario-vaxxed & PCR positive should isolate during 1st wk of infxn 11. Get vaxxed!
Minutes 57:00-57:50
Dr. Abu Hafiz:
Moderna telah pun diluluskan di USA dan banyak negara yang lain, tetapi seperti mana yang Dato' sebutkan, NPRA masih belum lagi meluluskan. (1)
Apa sebenarnya masalah kepada kita dalam menerima vaksin-vaksin yang telah diluluskan di dalam negara-negara maju? (2)
Dato' Dr. Musa Mohd Nordin:
Moderna telah diluluskan pada bulan 12 last year (US), 8 months ago. Kita luluskan dulu Pfizer, lepas tu Sinovac, lepas tu AZ. fda.gov/emergency-prep…