Phil Profile picture
Apr 19, 2020 455 tweets 147 min read
1/4

So far all existing data show smokers are underrepresented in Covid19 hospitalization data

2 studies from the US

1. medrxiv.org/content/10.110…

2.
2/4

13 studies from China

qeios.com/read/article/5… Image
4/4

The default "Smoking makes everything worse" is premature & irresponsible.

Afaik there are no data regarding cannabis consumption & Covid-19.

As for vaping 👇

reason.org/commentary/fda…
5/4

The data consistently show that former smokers are more at risk of serious outcomes than current smokers.
6/4 Image
7/4 More from France

"Our cross sectional study in both COVID-19 out- and inpatients strongly suggests that current smokers have a very much lower probability of developing symptomatic or severe SARS-CoV-2 infection as compared to the general population"

qeios.com/read/article/5…
8/

West Virginia USA: Current smoking rate was 25.2% in 2018.

Source (slide 6) dhhr.wv.gov/COVID-19/Pages… Image
9/ US Veterans Age 54-75

"Current smoking (OR 0.45, 95% CI 0.35-0.57), alcohol use disorder (OR 232 0.58, 95% CI 0.41- 0.83), and COPD (OR 0.67, 95%CI 0.50-0.88) were associated with decreased likelihood of Covid-19+."

medrxiv.org/content/10.110…
10/

France

"The protection associated with smoking in our study was very substantial (75% decrease in risk of infection), and deserves full attention."

medrxiv.org/content/10.110…
11/

Georgia USA (adult smoking rate was 16.1% in 2019)

"Among 305 patients hospitalized with COVID-19....Current smoking was reported for 5.2% of patients."

cdc.gov/mmwr/volumes/6…
12/

Oregon USA (adult smoking rate was 15.6% in 2019)

Out of 73 deaths, only one was a smoker.

govsite-assets.s3.amazonaws.com/U2Ui9gUiSxG1oS… Image
13/

1536 patients at 169 hospitals (121 in US, 48 in 10 other countries)

"5.5% were current smokers"

Smoking rates in all 11 countries are considerably higher.

nejm.org/doi/full/10.10… Image
14/

Korea (adult smoking rate was 21.1% in 2018)

Small study: Of 27 hospitalized, 5 (18.5%) were smokers.

jkms.org/DOIx.php?id=10…
15/

UK (adult smoking rate was 14.7% in 2018)

Of 5,924 patients, 8.7% were smokers.

medrxiv.org/content/10.110…
16/

UK (adult smoking rate was 14.7% in 2018)

Large study: Of 5,564 deaths, 7% were smokers.

medrxiv.org/content/10.110…
17/

Italy (adult smoking rate was 23.7% in 2016)

Of 441 hospitalized patients, 4.8% were smokers.

medrxiv.org/content/10.110…
18/

Spain

170 patients diagnosed with Covid-19

"A negative association was observed between tobacco consumption (0.52 95%CI 0.27-0.98) and the use of electronic cigarettes (0.45 95%CI 0.28-0.71) and SARS-CoV-2 infection."

jmir.org/preprint/19949…
19/

This isn't new evidence, but it's the peer-reviewed version of the systematic review & meta-analysis of 13 Chinese studies linked above.

link.springer.com/epdf/10.1007/s…
20/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 393 hospitalized patients, 5.1% were current smokers

(There might be some overlap between this study & the study in the first tweet of this thread)

nejm.org/doi/full/10.10…
21/

Switzerland (adult smoking rate was 27.1% in 2017)

Of 200 hospitalized patients, 4.5% were smokers.

medrxiv.org/content/10.110…
22/

Mexico (adult smoking rate was 17.6% in 2016)

Of 10,544 cases, 8.96% were smokers.

medrxiv.org/content/10.110…
23/

Kuwait (adult smoking rate was 22.5% in 2015)

Of 1,096 hospitalized cases, 4% were smokers.

Note: sample was 81% male. Male smoking rate in Kuwait was 43% in 2018.

medrxiv.org/content/10.110…
24/

China (adult smoking rate was 26.6% in 2018)

Of 202 hospitalized patients, 7.9% had a history of smoking.

journals.plos.org/plosntds/artic…
25/

3,799 patients in the UK

Smokers were half as likely as non-smokers to test positive for COVID-19

thelancet.com/journals/lanin… Image
26/

China (adult smoking rate was 26.6% in 2018)

Of 121 hospitalized patients, 5% were smokers.

medrxiv.org/content/10.110…
27/

Hong Kong (adult smoking rate was 10% in 2017)

Small study: of 37 hospitalized patients, 2 were current smokers (5.9%)

preprints.org/manuscript/202…
28/

China (adult smoking rate was 26.6% in 2018)

Of 285 hospitalized patients, 11% had a history of smoking.

researchsquare.com/article/rs-273…
29/

China (adult smoking rate was 26.6% in 2018)

Of 208 hospitalized patients, 5.8% were smokers

researchsquare.com/article/rs-238…
30/

China (adult smoking rate was 26.6% in 2018)

Of 220 hospitalized patients, 12.8% had a history of smoking. This one includes smoking index data. Smoking index number is cigarettes per day x years smoked.

researchsquare.com/article/rs-267…
31/

China (adult smoking rate was 26.6% in 2018)

Of 134 hospitalized patients, 10.4% were smokers.

researchsquare.com/article/rs-264…
32/

China (adult smoking rate was 26.6% in 2018)

Of 142 hospitalized patients, 9.1% were smokers

researchsquare.com/article/rs-236…
33/

Very small study from China

"Based on the expression of ACE2 in smoking individuals, it is inferred that long-term smoking might be a risk factor for 2019-nCoV, and in this study, We showed the evidence against that finding."

researchsquare.com/article/rs-247…
34/

China (adult smoking rate was 26.6% in 2018)

Reported: "There were more smokers (8.84% vs 1.36%, P = 0.006)...in the severe group than in the mild group."

Not mentioned: 5.1% of the 292 hospitalized patients had a history of smoking.

researchsquare.com/article/rs-232…
35/

New Mexico USA (adult smoking rate was 17.5% in 2017)

An outlier. Of 50 hospitalized patients, 48% were smokers. It's not clear whether current smokers or people with a history of smoking were counted.

medrxiv.org/content/10.110…
36/

China (adult smoking rate was 26.6% in 2018)

Of 101 hospitalized medical staff, 4 were smokers.

researchsquare.com/article/rs-287…
37/

Spain (adult smoking rate was 24% in 2019)

Of 54 patients with inflammatory rheumatic disease who were hospitalized with Covid-19, 5.56% were smokers.

medrxiv.org/content/10.110…
38/

France (adult daily smoking rate was 27% in 2017)

Of 108 cancer patients who tested positive, 19% were active smokers.

medrxiv.org/content/10.110…
39/

London, UK (adult smoking rate was 13.9% in 2018)

Of 75 cancer patients who tested positive, 9.3% were current smokers.

medrxiv.org/content/10.110…
40/

North Carolina, USA (adult smoking rate was 17.4% in 2019)

Of 86 hospitalized patients, 3.5% were current or former smokers.

medrxiv.org/content/10.110…
41/

China (adult smoking rate was 26.6% in 2018)

Of 145 hospitalized patients, 10.3% had a history of smoking.

This is a peer-reviewed article that appears to use the same data as the preprint in tweet 32, but the numbers are slightly different.

link.springer.com/article/10.100…
42/

China (adult smoking rate was 26.6% in 2018)

Of 125 hospitalized patients, 12.8% had a history of smoking

sciencedirect.com/science/articl…
43/

China (adult smoking rate was 26.6% in 2018)

Of 73 hospitalized patients, 10.9% had a history of smoking

sciencedirect.com/science/articl…
44/

Toronto, Canada (Ontario current smoking rate age 12 and over was 15.2% in 2017)

Of 226 hospitalized patients, 15.9% were current or former smokers

sciencedirect.com/science/articl…
45/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 257 critically ill patients, 13% were current or former smokers

sciencedirect.com/science/articl…
46/

UK

"...we observed an apparently protective effect, in the tested sub-population, of smoking on the risk of having a positive PCR for SARS-CoV-2 infection (OR [95% CI] 0.73 [0.65 to 0.81]; p=9.49x10-9)..."

No hospitalization data reported.

medrxiv.org/content/10.110…
47/

China (adult male smoking rate was 50.5% in 2018)

Of 125 male patients with mild symptoms, 65.6% were current smokers.

Notes:
Median age was 35
Patients with severe symptoms were excluded from study

researchsquare.com/article/rs-295…
48/

China (adult smoking rate was 26.6% in 2018)

Of 50 critically ill patients admitted to ICU, 18% were current smokers

researchsquare.com/article/rs-296…
49/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 5,051 patients diagnosed with Covid-19, 3.6% were current smokers

medrxiv.org/content/10.110…
50/

Earth (adult smoking rate was ~20% in 2015)

Of 96,032 hospitalized patients, 9.88% were current smokers.

Note: 65.9% of sample was from North America
Europe 17.3%
Asia 7.9%
Africa 4.6%
Australia 0.6%

thelancet.com/journals/lance…
51/

Monterey County, California, USA (adult smoking rate was 11.7% in 2017)

Of 362 confirmed cases, 4% were current or former smokers

co.monterey.ca.us/government/dep… Image
52/

China (adult smoking rate was 26.6% in 2018)

Of 307 hospitalized patients, 21.8% had a history of smoking

researchsquare.com/article/rs-303…
53/

China (adult smoking rate was 26.6% in 2018)

Of 201 hospitalized patients, 7.0% had a history of smoking

researchsquare.com/article/rs-304…
54/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 222 hospitalized patients, 11.2% had a "smoke habit"

researchsquare.com/article/rs-304…
55/

Israel (adult smoking rate was 19.1% in 2018)

Of 4,353 people who tested positive, 11.8% were current smokers

medrxiv.org/content/10.110…
56/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 1,000 who tested positive, 4.9% were active smokers

Of 850 hospitalized, 4.12% were active smokers

Of 236 in ICU, 4.2% were active smokers

medrxiv.org/content/10.110…
56a/

There appears to be a considerable amount of overlap between the studies in tweet 56 & tweet 45.
57/

Mexico (adult smoking rate was 17.6% in 2016)

Of 51,633 who tested positive, 8.5% were smokers

Of 98,567 who tested negative, 9.8% were smokers

Of 26,933 suspected cases, 9.1% were smokers

Unclear whether numbers refer to current or ever smokers

medrxiv.org/content/10.110…
58/ Spain (adult smoking rate was 24% in 2019)

Of 2,226 hospitalized patients, 7.1% were current smokers

medrxiv.org/content/10.110…
59/

Earth (adult smoking rate was ~20% in 2015)

Of 17,124 admitted patients from 35 countries, 5.74% were smokers. It's unclear whether they were current smokers.

media.tghn.org/medialibrary/2…
60/

Spain (adult smoking rate was 24% in 2019)

Of 47 hospitalized patients, 21% were smokers. It's unclear whether they were current smokers.

medrxiv.org/content/10.110…
61/

Mexico (adult smoking rate was 17.6% in 2016)

Of 7,497 patients who tested positive, 9.4% were smokers

medrxiv.org/content/10.110…
62/

France (adult daily smoking rate was 27% in 2017)

Of 152 hospitalized patients, 6.6% were smokers.

medrxiv.org/content/10.110…
63/

France (adult daily smoking rate was 27% in 2017)

Of 50 hospitalized patients, 1 was a current smoker (2%)

Note: "Inpatients with pre-existing unstable chronic disorders...were excluded."

medrxiv.org/content/10.110…
64/

San Francisco, USA (adult smoking rate was 9.5% in 2015)

Of 33 people who tested positive, zero were current smokers

medrxiv.org/content/10.110…
65/

Michigan, USA (adult smoking rate was 18.9% in 2019)

Of 172 hospitalized patients, 26% had a history of smoking

medrxiv.org/content/10.110…
66/

USA (adult current smoking rate was 13.7% in 2018)

Of 368 patients hospitalized at VA Medical Centers, 14.1% were smokers

Notes:

It's not clear if smoking was current or ever.

Veterans traditionally have higher smoking rates than total population

medrxiv.org/content/10.110…
67/

Mexico (adult smoking rate was 17.6% in 2016)

Of 31,522 who tested positive, 8.7% were smokers

Of 12,690 hospitalized, 9.5% were smokers

medrxiv.org/content/10.110…
68/

London, UK (adult smoking rate was 13.9% in 2018)

Of 8,985 suspected cases, 11.7% were current smokers.

Note: data from 4 boroughs only. "...all four feature in the top decile of the most socially deprived boroughs in England"

medrxiv.org/content/10.110…
69/

Philadelphia, USA (adult current smoking rate was 18-19% in 2017)

Of 104 patients with moderate to severe hypoxic respiratory failure, 44.43% were smokers

Note: In this study, smokers were less likely to require intubation than non-smokers

medrxiv.org/content/10.110…
70/

China (adult smoking rate was 26.6% in 2018)

Of 24 patients hospitalized with Covid-19, 2 were smokers (8.33%)

Of 79 patients hospitalized with influenza in the same 20-day period, 12 were smokers (15.19%)

researchsquare.com/article/rs-311…
71/

Spain (adult smoking rate was 24% in 2019)

Of 6,165 hospitalized patients, 5.3% were current smokers

medrxiv.org/content/10.110…
72/

Mexico (adult smoking rate was 17.6% in 2016)

Of 400 hospitalized patients, 12% were smokers. Smokers' survival rate was slightly lower than non-smokers.

Note: unclear if this is a random sample.

medrxiv.org/content/10.110…
72a/

The lead author of the study in the previous tweet confirmed that the sample was indeed random.
73/

China (adult smoking rate was 26.6% in 2018)

Of 326 adult patients, 12.58% were smokers.

Note: Unclear whether current or ever

researchsquare.com/article/rs-307…
74/

China (adult smoking rate was 26.6% in 2018)

Of 138 patients hospitalized with severe Covid-19, 5.8% were smokers

Note: unclear whether current or ever

researchsquare.com/article/rs-307…
75/

Ohio, USA (adult current smoking rate was 20.5% in 2019)

Of 22 hospitalized patients, 45.5% had a history of smoking

medrxiv.org/content/10.110…
76/

Philadelphia, USA (adult current smoking rate was 18-19% in 2017)

Of 129 hospitalized patients, 45.7% were current smokers

medrxiv.org/content/10.110…
77/

Detroit and Chicago, USA

Adult smoking rate in Wayne County (Detroit) was 22.6% in 2015. In Chicago it was 16.8% in 2018

Of 39 patients with multiple sclerosis who tested positive, 15.4% were smokers. Of 20 hospitalized patients, 30% were smokers

medrxiv.org/content/10.110…
78/

San Francisco, USA (adult smoking rate was 9.5% in 2015)

Of 26 patients admitted to ICU, 6 were current or former smokers (23%)

medrxiv.org/content/10.110…
79/

Mexico (adult smoking rate was 17.6% in 2016)

Updated (old number)

Of 50,411 (31,522) who tested positive, 8.68 (8.7)% were smokers

Logistic regression table. Columns are:

Hospitalized, intubated, death & death (controlled for hospitalization)

medrxiv.org/content/10.110… Image
80/

Brazil (adult daily smoking rate was 15.4% in 2015)

Of 48 hospitalized patients with suspected cases, 8.3% were current smokers

jamanetwork.com/journals/jaman…
81/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 1,074 hospitalized patients, 4.2% were current smokers

Note: New York City metro area

jamanetwork.com/journals/jama/…
82/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 1,376 hospitalized patients, 11.4% were current smokers

nejm.org/doi/full/10.10…
83/

Earth (adult smoking rate was ~20% in 2015)

Of 8,910 hospitalized patients, 5.5% were current smokers

Patients per continent (countries):

Europe (IT, ES, GB, TR, DE) 64.6%
Asia (CN, KR, JP) 18.2%
North America (US, CA) 17.2%

nejm.org/doi/full/10.10…
84/

Not new information; it's the peer-reviewed version of the study in tweet 56. Numbers didn't change.

bmj.com/content/369/bm…

85/

UK (adult smoking rate was 14.7% in 2018)

Updated and peer-reviewed version of study in tweet 15

(Old numbers: Of 5,924 patients, 8.7% were smokers)

New numbers:

Of 14,184 hospitalized patients
6% were current smokers
30.8% were previous smokers

bmj.com/content/369/bm…
86/

Turkey (adult smoking rate was 27.2% in 2016)

Of 40 Covid-19 patients with olfactory loss, 55% were smokers.

Note: not specified if current or ever

researchsquare.com/article/rs-317…
87/

China (adult smoking rate was 26.6% in 2018)

Of 751 hospitalized patients, 6% were current smokers

Note: 232 patients with cancer, 519 without. Current smoking rate was 6% in both groups.

thelancet.com/journals/lanon…
88/

USA, Spain, Canada (adult smoking rates were 13.7%, 24% & 15.8% in 2018-19)

Of 838 Covid-19 patients with a current or past diagnosis of cancer, 5.13% were current smokers. 38.9% were former smokers

Patients:
USA 88%
Spain 7%
Canada 5%

thelancet.com/journals/lance…
89/

Italy (adult smoking rate was 23.7% in 2016)

Of 56 patients hospitalized for neurological diseases who had Covid-19, 1.8% was a current smoker

Of 117 patients hospitalized for neurological diseases who didn't have Covid-19, 6% were current smokers

n.neurology.org/content/early/…
90/

Earth (adult smoking rate was ~20% in 2015)

Of 14,712 positive cases, 8.67% had "nicotine dependence"

Patients:

USA 47% (adult current smoking rate was 13.7% in 2018)
Outside USA 53%

mayoclinicproceedings.org/article/S0025-…
91/

China (adult smoking rate was 26.6% in 2018)

Of 31 hospitalized patients, 2 were current smokers (6%)

Note: Median age was 39

mja.com.au/journal/2020/2…
92/

New York City, USA

Of 31 HIV-positive patients hospitalized for Covid-19, 13 were current or former smokers (42%)

Note: Cigarette smoking rate is high among HIV+ people. National Cancer Institute estimated ~40% in US as of Jan 2020

academic.oup.com/cid/advance-ar…
93/

Virginia, USA (adult smoking rate was 14.9% in 2019)

Of 135 military hospital patients who tested positive, 10.4% used tobacco & another 9.6% had used tobacco in the past.

Of 15 hospitalized, one used tobacco (6.7%), none formerly.

academic.oup.com/cid/advance-ar…
94/

Wayne County, Michigan, USA (Adult smoking rate was 22.6% in 2015)

Of 197 hospitalized patients, 5.6% were current tobacco smokers

Of 74 severe cases, 8.3% were current tobacco smokers

academic.oup.com/cid/advance-ar…
95/

Washington State, USA (Adult smoking rate was 12% in 2019)

Of 86 hospitalized cases, 26% were ever smokers

Of 41 severe cases, 24% were ever smokers

Note: 35% of patients were admitted from a senior home or a skilled nursing facility

academic.oup.com/cid/advance-ar…
96/

China (adult smoking rate was 26.6% in 2018)

Of 275 hospitalized patients, 2.2% had a history of smoking

Of 45 severe patients, zero had a history of smoking

academic.oup.com/ofid/advance-a…
97/

China (adult smoking rate was 26.6% in 2018)

Of 84 cases, 19% were smokers. Not clear if current or ever

academic.oup.com/cid/advance-ar…
98/

Italy (adult smoking rate was 23.7% in 2016)

Of 85 hospitalized patients, 20% had a history of smoking

academic.oup.com/eurheartj/arti…
99/

China (adult smoking rate was 26.6% in 2018)

Of 323 hospitalized patients, 11.8% had a history of smoking

academic.oup.com/cid/advance-ar…
100/

Malaysia (smoking rate was 21.3% in 2019)

Of 86 deaths, 19.8% had a history of smoking

Note: all info comes from 2 news articles

1. nst.com.my/news/nation/20…

2. thestar.com.my/news/nation/20…
101/

British Columbia, Canada (tobacco smoking rate ages 12 & over was 12% in 2018)

Of 117 ICU patients, 13.7% were current or former tobacco smokers

cmaj.ca/content/cmaj/e…
102/

The preprint in tweet 35 was published. In this version, the authors stated that 24 out of 50 had a history of smoking. Somehow the number changed to 51% -- probably an error.

tandfonline.com/doi/figure/10.…

103/

China (adult smoking rate was 26.6% in 2018)

Of 499 hospitalized patients, 6.6% had a history of smoking

link.springer.com/article/10.100…
104/

China (adult smoking rate was 26.6% in 2018)

Of 115 patients, 8.7% were current smokers

link.springer.com/article/10.118…
105/

Indiana, USA (adult current smoking rate was 21.1% in 2019)

Of 144 patients admitted to ICU, 27.1% were smokers

Note: Not specified if current or ever

medrxiv.org/content/10.110…
106/

Israel

medrxiv.org/content/10.110…

"...even among SARS-CoV-2 positive patients, we found no evidence of significant association between current or past smoking and disease severity, as reflected by death during hospitalization or by need for mechanical ventilation." Image
107/

China (adult smoking rate was 26.6% in 2018)

Of 77 hospitalized young adults (age 65 and under), 3 were smokers (4%)

Of 40 young adults who died, 1 was a smoker (3%)

researchsquare.com/article/rs-313…
108/

China (adult smoking rate was 26.6% in 2018)

Of 588 hospitalized adults, 6.5% were current smokers

medrxiv.org/content/10.110… Image
109/

China (adult smoking rate was 26.6% in 2018)

Of 101 patients, 8 were smokers (7.9%)

Note: not specified if current or ever

heart.bmj.com/content/early/…
110/

China (adult smoking rate was 26.6% in 2018)

Of 274 hospitalized patients, 4.4% were current smokers & 2.6% were former smokers

bmj.com/content/368/bm…
111/

Denmark (adult smoking rate was 19.1% in 2016)

Of 407 patients hospitalized with symptoms of Covid-19, 21.3% were active smokers.

117 patients tested positive for SARS-CoV-2 & 290 negative.

7.1% of those who tested positive were active smokers

medrxiv.org/content/10.110…
112/

London, UK (adult smoking rate was 13.9% in 2018)

Of 93 patients who had CT pulmonary angiography, 14.0% were current smokers

medrxiv.org/content/10.110…
113/

Italy (adult smoking rate was 23.7% in 2016)

Of 132 hospitalized patients who required oxygen therapy, 9.1% were active smokers

onlinelibrary.wiley.com/doi/10.1002/dm…
114/

China (adult smoking rate was 26.6% in 2018)

Of 733 critically ill patients, 6.1% were ever smokers

papers.ssrn.com/sol3/papers.cf…
115/

Spain (adult smoking rate was 24% in 2019)

Of 37 HIV-positive patients with confirmed or suspected cases of Covid-19, 70% were current or past smokers.

Note: smoking rates among people living with HIV are higher than in the general population

papers.ssrn.com/sol3/papers.cf…
116/

Poland (university student current smoking was 23.78% & current vaping was 8.33% in 2016)

Of 52 students (51 male) age 19-26 who tested positive, 7.8% were current smokers & 5.9% were current vapers

Note: not mentioned if any were dual users

medrxiv.org/content/10.110…
117/

Spain (adult smoking rate was 24% in 2019)

Of 188 hospitalized patients, 4.8% were active smokers & 18.1% were ex-smokers

biorxiv.org/content/10.110…
118/

Belgium (adult current smoking rate was 19.4% in 2018)

Of 86 patients, 10.5% were smokers

Note: all patients were not hospitalized at time of study

onlinelibrary.wiley.com/doi/full/10.10… Image
119/

Belgium (adult current smoking rate was 19.4% in 2018)

Of 47 patients with severe Covid-19, zero were smokers

authorea.com/users/326467/a…
120/

UK (adult smoking rate was 14.7% in 2018)

Of 33 hospitalized patients, zero were current smokers

authorea.com/users/316818/a… Image
121/

Iran (adult cigarette smoking rate was 12% in 2019. Adult smoking rate including hookah was ~20% in 2019)

Of 490 hospitalized patients, 14% were smokers.

Note: Iran population smoking prevalence statistics are questionable

medrxiv.org/content/10.110…
122/

Iran (adult cigarette smoking rate was 12% in 2019. Adult smoking rate including hookah was ~20% in 2019)

Of 193 hospitalized patients, 7.3% were cigarette smokers & 7.8% were waterpipe users. Zero dual users.

Note: see note in previous tweet

tobaccoinduceddiseases.org/Descriptive-ch… Image
123/

Poland (adult smoking rate was 26% in 2019)

Of 1,087 non-hospitalized patients, 11.2% said they smoked

mp.pl/paim/issue/art…
124/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 3,406 hospitalized patients, 23.3% had a history of smoking

572 patients age 50 & under: 13.3% had a history of smoking

2834 patients over 50: 25.3% had a history of smoking

onlinelibrary.wiley.com/doi/abs/10.100…
125/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 200 hospitalized patients, 32.5% were current or former smokers

Note: Hospital in Bronx, where smoking rate is higher than NYC total

metabolismjournal.com/article/S0026-…
126/

China (adult smoking rate was 26.6% in 2018)

Of 339 hospitalized patients, 8.3% were current smokers

sciencedirect.com/science/articl…
127/

Spain (adult smoking rate was 24% in 2019)

Of 3,127 hospitalized patients, 7.1% were current smokers

Of 460 deaths, 9.6% were current smokers

mdpi.com/2077-0383/9/6/…
128/

Belgium (adult current smoking rate was 19.4% in 2018)

Of 299 positive cases, 7.4% were smokers

researchsquare.com/article/rs-331…
129/

The large studies in tweets 13, 50, and 83 have been retracted.

statnews.com/2020/06/04/lan…
130/

China (adult smoking rate was 26.6% in 2018)

Of 675 patients, 9.5% were current smokers and 4.9% were former smokers

researchsquare.com/article/rs-322…
131/

Rajasthan, India (adult current smoking rate was 13.2% in 2016-17)

Of 234 hospitalized young adults (median age 35), 8.5% were smokers

Note: results likely complicated by smokeless tobacco use (14.1% including 2.6% dual use in 2016-17)

medrxiv.org/content/10.110…
132/

Italy (adult smoking rate was 23.7% in 2016)

Of 962 patients hospitalized with Covid-19 pneumonia, 28.6% were current or former smokers

medrxiv.org/content/10.110…
133/

China (adult smoking rate was 26.6% in 2018)

Of 186 hospitalized patients ages 60 and over, 16.7% had a history of smoking

researchsquare.com/article/rs-311…
134/

Mexico (adult smoking rate was 17.6% in 2016)

Of 72 hospitalized patients, 25% were smokers.

Notes:

Not specified if current or ever

Results of smaller studies from Mexico are likely included in larger samples, e.g. studies in tweets 67 and 79

authorea.com/users/330400/a…
135/

Switzerland (adult smoking rate was 27.1% in 2017)

Of 120 patients admitted to ICU, 12.5% were active smokers

papers.ssrn.com/sol3/papers.cf…
136/

Germany (adult smoking rate was 25% in 2017)

Of 60 hospitalized patients, 10% were smokers

Note: not stated if current or ever

papers.ssrn.com/sol3/papers.cf…
137/

China (adult smoking rate was 26.6% in 2018)

Of 142 patients, 9.2% were smokers

Note: not specified if current or ever

researchsquare.com/article/rs-328…
137a/

Correction: The text & the table contradict each other, but it appears 9.2% had *a history* of smoking ImageImage
138/

Mexico (adult smoking rate was 17.6% in 2016)

Updated information

Of 236,439 people with suspected viral respiratory disease, 9.1% were current smokers

Of 89,756 with positive Covid-19 diagnosis, 8.3% were current smokers

medrxiv.org/content/10.110…

continued
138a/

Of 146,683 with negative Covid-19 diagnosis, 9.5% were current smokers

"Notably, smoking was not associated with a higher risk for adverse outcomes and hospitalization. Smokers were also less likely to be diagnosed with COVID-19 compared to non-smokers."
139/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 57 multiple myeloma patients who were diagnosed with Covid-19, 37% were current or former smokers

medrxiv.org/content/10.110…
140/

China (adult smoking rate was 26.6% in 2018)

Of 76 hospitalized patients, 3 were current smokers (4%)

papers.ssrn.com/sol3/papers.cf…
141/

Italy (adult smoking rate was 23.7% in 2016)

Of 296 hospitalized patients, 17.2% had a history of smoking

papers.ssrn.com/sol3/papers.cf…
142/

China (adult smoking rate was 26.6% in 2018)

Of 171 hospitalized patients, 8.2% were "persistent" smokers. Another 4.7% had quit.

papers.ssrn.com/sol3/papers.cf…
143/

Quebec, Canada (smoking ages 12 & over was 17.5% in 2018)

Of 134 who tested positive, 11.2% said they were active smokers and 32.8% said they were past smokers

Note: patients who were dead or hospitalized at the time of the survey were excluded

cmaj.ca/content/early/…
144/

China (adult smoking rate was 26.6% in 2018)

Of 81 patients with severe Covid-19, three were smokers (3.7%)

ccforum.biomedcentral.com/articles/10.11…
145/

Earth (adult smoking rate was ~20% in 2015)

Of 600 diagnosed cases in individuals with rheumatic disease from 40 countries, 25% were ever smokers

Note: 71% of sample was female

ard.bmj.com/content/annrhe…
146/

China (adult smoking rate was 26.6% in 2018)

Of 133 hospitalized cases, 10.5% were smokers

onlinelibrary.wiley.com/doi/full/10.10…
147/

China (adult smoking rate was 26.6% in 2018)

Of 454 hospitalized cases, 9.7% were smokers

atsjournals.org/doi/10.1164/rc…
148/

Brazil (adult daily smoking rate was 15.4% in 2015)

Of 159 who tested positive, 3.1% said they were current smokers, and 11.9% said they were former smokers

Note: 68.6% of respondents were female

sciencedirect.com/science/articl…
149/

Greece (adult smoking rate was 27.1% in 2017)

Of 22 hospitalized cases, 13% were smokers

link.springer.com/article/10.100…
150/

Spain (adult smoking rate was 24% in 2019)

Of 38 patients with arterial thrombotic complications who tested positive, 13.2% were smokers

Of 49 patients with arterial thrombotic complications who didn't test positive, 22.5% were smokers

sciencedirect.com/science/articl…
151/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 4,458 people who tested positive, 6.5% were current smokers & 20.2% were former smokers

Of 2,296 hospitalized, 6.1% were current smokers & 24.6% were former smokers

bmj.com/content/369/bm…
152/

Georgia, USA (adult smoking rate was 16.1% in 2019)

Of 49 people with diabetes who tested positive, 2 were active smokers (4%) & 9 were former smokers (18%)

Note: 73% of patients were female

diabetesresearchclinicalpractice.com/article/S0168-…
153/

Italy (adult smoking rate was 23.7% in 2016)

Of 65 patients hospitalized with severe Covid-19 pneumonia, 2 were smokers (3.1%)

Note: 86.2% of patients were male

ejinme.com/article/S0953-…
154/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 193 hospitalized patients, 30% had a history of smoking

sciencedirect.com/science/articl…
155/

Italy (adult smoking rate was 23.7% in 2016)

Of 78 hospitalized patients, 26.9% were smokers

sciencedirect.com/science/articl…
156/

China (adult smoking rate was 26.6% in 2018, and smoking rate ages 15-24 was 18.6% in 2018)

Of 14 infected patients ages 10-24, one was an ever or current smoker (7.1%)

Of 32 infected patients ages 25-35, four were ever or current smokers (12.5%)

sciencedirect.com/science/articl…
157/

Chicago, USA (adult smoking rate was 16.8% in 2018)

Of 486 hospitalized patients, 33.5% were current or former smokers

journals.sagepub.com/doi/10.1177/01…
158/

Switzerland (adult smoking rate was 27.1% in 2017)

Of 103 patients with positive diagnoses, 8.8% were current smokers, and 18.4% were former smokers

journals.sagepub.com/doi/10.1177/01…
159/

China (adult smoking rate was 26.6% in 2018)

Of 150 hospitalized patients, 3 had a history of smoking (2%)

link.springer.com/article/10.100…
160/

Colorado, USA (adult smoking rate was 14.5% in 2019, and 5.3% of adults reported e-cigarette use in 2017)

Of 44 patients admitted to ICU, two were smokers and/or vapers (4.5%)

journalacs.org/article/S1072-…
161/

China (adult smoking rate was 26.6% in 2018)

Of 21 severe or critical cases, 28.6% had a history of smoking

ascpt.onlinelibrary.wiley.com/doi/full/10.11…
162/

Italy (adult smoking rate was 23.7% in 2016)

Of 31 patients ages 65 & over hospitalized with severe Covid-19, 25.8% had a history of smoking

journalofinfection.com/article/S0163-…
163/

China (adult smoking rate was 26.6% in 2018)

Of 1,004 patients hospitalized with confirmed or suspected Covid-19, 15% had a history of smoking.

Of the 144 confirmed cases, 14% had a history of smoking

thelancet.com/pdfs/journals/…
164/

China (adult smoking rate was 26.6% in 2018)

Of 291 confirmed cases, 8.9% had a history of smoking

onlinelibrary.wiley.com/doi/full/10.11…
165/

Italy (adult smoking rate was 23.7% in 2016)

Of 31 Covid-19 patients with acute coronary syndrome, 35.5% were current smokers

onlinelibrary.wiley.com/doi/full/10.10…
166/

China (adult smoking rate was 26.6% in 2018)

Of 154 patients with Covid-19 pneumonia, 6.29% had a history of smoking

Of 100 patients with other viral pneumonia, 16% had a history of smoking

link.springer.com/article/10.100…
167/

China (adult smoking rate was 26.6% in 2018)

Of 110 hospitalized & released patients with non-critical cases, 11.8% were smokers

Note: not specified if ever or current

erj.ersjournals.com/content/early/…
168/

China (adult smoking rate was 26.6% in 2018)

Of 15 asymptomatic patients, one was a smoker (6.7%)

onlinelibrary.wiley.com/doi/full/10.10…
169/

China (adult smoking rate was 26.6% in 2018)

Of 545 with mild or moderate cases, 22.39% had a history of smoking

papers.ssrn.com/sol3/papers.cf…
170/

Hong Kong (adult smoking rate was 10% in 2017)

Of 18 hospitalized patients (ages 18-60), one was a smoker (6%)

academic.oup.com/ofid/advance-a…
171/

China (adult smoking rate was 26.6% in 2018)

Of 2,877 hospitalized patients, 6.6% were smokers

Note: not specified if current or ever

academic.oup.com/eurheartj/adva…
172/

China (adult smoking rate was 26.6% in 2018)

Of 154 hospitalized patients, 7.8% were smokers

papers.ssrn.com/sol3/papers.cf…
173/

Germany (adult smoking rate was 25% in 2017)

Of 14 patients who experienced abnormal taste and/or smell, 3 were regular smokers (21%)

papers.ssrn.com/sol3/papers.cf…
174/

Italy (adult smoking rate was 23.7% in 2016)

Of 508 positive diagnoses, 5.9% were current smokers & 26.8% were former smokers

Of 295 hospitalized, 4.1% were current smokers & 33.5% were former smokers

papers.ssrn.com/sol3/papers.cf… Image
175/

Earth (adult smoking rate was ~20% in 2015)

Of 1,113 patients from 24 countries who were diagnosed with Covid-19 around the time of surgery, 9.5% were current smokers

thelancet.com/pdfs/journals/…

Countries 👇 Image
176/

Countries (adult smoking rate)

France (27% in 2017)
Italy (23.7% in 2016)
Spain (24% in 2019)
Belgium (19.4% in 2018)

Of 702 patients with mild-to-moderate cases, 15% were smokers

jvoice.org/article/S0892-… Image
177/

Texas, USA (adult smoking rate was 14.4% in 2019 & 4.7% vaped in 2017)

Of 14 hospitalized patients, 3 were current tobacco users (21%), one was a vaper (7%), and one was a marijuana user (7%)

Note: not stated if any were dual (or triple) users

onlinelibrary.wiley.com/doi/full/10.10…
178/

France (adult daily smoking rate was 27% in 2017)

Of 1,029 people with diabetes hospitalized with Covid-19, 5.5% were current tobacco users & 37.9% were former tobacco users

Type 1: 3.0%
Type 2: 88.5%
Other: 5.4%
Diagnosed on admission: 3.1%

link.springer.com/article/10.100…
179/

Earth (adult smoking rate was ~20% in 2015)

Of 1,379 positive diagnoses in people with inflammatory bowel disease in 40+ countries, 4.8% were current smokers

Of 413 hospitalized patients, 6.8% were current smokers

Of 80 admitted to ICU, 5% were current smokers

continued
179a/

Of 64 who needed mechanical ventilation, 3.1% were current smokers

Of 48 who died, 8.3% were current smokers

Note: smoking among people with IBD may differ from general population

covidibd.org/current-data/
180/

Portugal (adult smoking rate was 22.7% in 2016)

Of 14 workers at a hospital rheumatology dept. who tested positive, 4 had a history of smoking (28.6%)

Of 8 patients who tested positive, 1 was an active smoker (12.5%) & 3 were past smokers (37.5%)

medrxiv.org/content/10.110…
181/

China (adult smoking rate was 26.6% in 2018)

Of 148 patients hospitalized with mild to moderate cases, 5.4% had a history of smoking

Of 56 patients whose cases progressed to severe, 5.4% had a history of smoking

papers.ssrn.com/sol3/papers.cf…
182/

China (adult smoking rate was 26.6% in 2018)

Of 85 who tested positive, 11.8% were current or former smokers

researchsquare.com/article/rs-326…
183/

China (adult smoking rate was 26.6% in 2018)

Of 219 hospitalized patients, 23.3% were smokers

Note: not specified if current or ever

researchsquare.com/article/rs-325…
184/

China (adult smoking rate was 26.6% in 2018)

Of 56 patients with cancer who tested positive for SARS-CoV-2, 9% had a history of smoking

researchsquare.com/article/rs-332…
185/

China (adult smoking rate was 26.6% in 2018)

Of 289 hospitalized patients, 9.7% had a history of smoking

authorea.com/users/320592/a…
186/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 388 hospitalized patients, 11.6% were smokers

Of 61 patients admitted to ICU, 4.9% were smokers

Note: not specified if current or ever

sciencedirect.com/science/articl…
187/

Italy (adult smoking rate was 23.7% in 2016)

Of 133 people with hypertension who tested positive, three were active smokers (2.3%)

academic.oup.com/ajh/advance-ar…
188/

UK (adult smoking rate was 14.7% in 2018)

Of 419 pregnant women hospitalized with SARS-CoV-2 infections, 4.8% were current smokers

Note: results may be complicated because pregnant women are advised to not smoke

bmj.com/content/369/bm…
189/

Spain (adult smoking rate was 24% in 2019)

Of 82 pregnant women who were infected, 7.3% were smokers

Notes:

Not specified if current or ever

Results may be complicated because pregnant women are advised to not smoke

Most cases mild/asymptomatic

jamanetwork.com/journals/jama/…
190/

USA, Spain, Italy, UK (adult smoking rates were 13.7, 24, 23.7 & 13.9%)

Of 66 Covid-19 patients who had LVO strokes, 8 were active smokers (12.1%) However, the authors reported '19%' without providing any clue as to how they arrived at that number

papers.ssrn.com/sol3/papers.cf…
191/

France (adult daily smoking rate was 27% in 2017)

Of 2,878 hospitalized patients, 13.5% were smokers

Note: not specified if current or ever

papers.ssrn.com/sol3/papers.cf…
192/

France (adult daily smoking rate was 27% in 2017)

Of 310 hospitalized patients, 4.2% were active smokers

Of 102 admitted to ICU, 3.9% were active smokers

papers.ssrn.com/sol3/papers.cf…
193/

Switzerland (adult smoking rate was 27.1% in 2017)

Of 80 people infected with SARS-CoV-2, one was a current smoker (1.3%).

62 patients were hospitalized, including 21 who were intubated and/or died, but this smoker was treated as an outpatient.

papers.ssrn.com/sol3/papers.cf…
194/

China (adult smoking rate was 26.6% in 2018)

Of 306 patients hospitalized with severe cases, 5 were current smokers (1.6%)

papers.ssrn.com/sol3/papers.cf…
195/

Suffolk County, NY, USA (adult smoking rate was 17.8% in 2015. NY State current smoking was 12.8% in 2019)

Of 4,404 patients exhibiting symptoms, 6% were current smokers & 2% were former smokers.

Note: only 58% of 2,828 total tests were positive

papers.ssrn.com/sol3/papers.cf…
196/

China (adult smoking rate was 26.6% in 2018)

Of 148 hospitalized patients, 11.49% were current smokers & 2.7% were past smokers

Of 29 severe cases, 20.69% were current smokers & 6.9% were past smokers

papers.ssrn.com/sol3/papers.cf…
197/

In the words of the lead author of the study in tweet 171:

"It’s current smoker. although likely underreported, please note that the mean age is about 60 and half was female..."

198/

China (adult smoking rate was 26.6% in 2018)

Systematic review & meta-analysis of Covid-19 patients in China. Undoubtedly there is a significant amount of overlap with other data in this thread.

Of 5,094 patients in 35 studies, 9.93% were smokers

papers.ssrn.com/sol3/papers.cf…
199/

Iran (adult cigarette smoking rate was 12% in 2019. Adult smoking rate including hookah was ~20% in 2019)

Of 19 positive patients who underwent CV surgery, 2 were smokers (10.5%)

Note: Iran population smoking prevalence statistics are questionable

papers.ssrn.com/sol3/papers.cf…
200/

Bradford, UK (adult smoking rate was 18.9% in 2017)

Of 524 confirmed and suspected cases, 11.5% were smokers

Note: not specified if current or ever

medrxiv.org/content/10.110…
201/

Broward County, Florida, USA (adult smoking rate was 15% in 2017)

Of 255 hospitalized patients, 6.3% were current smokers & 11.7% were former smokers

Of 46 deaths, 39% were current or former smokers. (Shameful to lump them together)

medrxiv.org/content/10.110…
202/

France (adult daily smoking rate was 27% in 2017)

Of 246 patients hospitalized with severe Covid-19 pneumonia, 25.2% were active or past smokers

medrxiv.org/content/10.110…
203/

France: "54,358 patients with clinically suspected Covid-19"

"Tested smokers are less likely to be PCR+ (46% are PCR+ vs 66%, p<0.0001)."

"some patients with a priori higher respiratory risk (any comorbidity, smokers) are less likely to be tested"

medrxiv.org/content/10.110…
204/

The lead author of the study in tweet 200 confirmed that it is current

205/

Spain (adult smoking rate was 24% in 2019)

Of 339 deaths with confirmed or probable diagnoses, 30.7% had a history of smoking

Note: average age was 80.5

medrxiv.org/content/10.110…
206/

Massachusetts, USA (adult smoking rate was 13.4% in 2019)

Of 104 employees at one grocery store, 25 were smokers (24%)

Of the 21 who tested positive, 1 was a smoker (4.8%)

"...cigarette smokers had a 90% risk reduction..."

medrxiv.org/content/10.110…
207/

China (adult smoking rate was 26.6% in 2018)

Of 138 people with positive diagnoses, 13.0% were smokers

Note: not specified if current or ever

researchsquare.com/article/rs-323…
208/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 28 pregnant women who tested positive, 1 smoked during pregnancy (3.6%)

Of 287 pregnant women who did not test positive, 12 smoked during pregnancy (4.2%)

researchsquare.com/article/rs-344…
209/

China (adult smoking rate was 26.6% in 2018)

Of 138 patients with severe and critical cases, 22.3% had a history of smoking

researchsquare.com/article/rs-314…
210/

Ireland (adult smoking rate was 17.1% in 2019)

Of 82 hospitalized patients, 25.6% were current or previous smokers

Note: "The hospital is located in Dublin’s north inner city with many of Ireland’s most deprived neighbourhoods are situated..."

researchsquare.com/article/rs-340…
211/

London, UK (adult smoking rate was 13.9% in 2018)

Of 188 health care workers who were tested, 11.7% were current smokers & 17.6% were former smokers

Of 38 who tested positive at least once, 10.5% were current smokers & 18.4% were former smokers

medrxiv.org/content/10.110…
212/

China (adult smoking rate was 26.6% in 2018)

Of 238 hospitalized patients, 2.9% were current smokers

Notes:

Patients who died (n=4) were excluded
15.1% of cases were severe or critical
57.1% of patients were female

medrxiv.org/content/10.110…
213/

China (adult smoking was 26.6% in 2018)

Of 1,007 patients with mild or moderate cases, 8.7% had a history of smoking

Of 244 whose illness progressed to severe or critical, 7% had a smoking history

Of 43 who died, 1 had a smoking history (2.3%)

clinicalmicrobiologyandinfection.com/article/S1198-…
214/

Germany (adult smoking rate was 25% in 2017)

Of 105 hospitalized patients, 27% were current or ex-smokers

Of 14 "with radiologic signs consistent with bilateral COVID-19 pneumonitis or COVID-19 associated ARDS", 9 were current or ex-smokers (64%)

nature.com/articles/s4137…
215/

China (adult smoking was 26.6% in 2018)

Of 135 hospitalized patients, 3.0% were current smokers

Note: patients who died, who required ICU within 14 days, or whose hospital stay was less than 14 days were excluded

sciencedirect.com/science/articl…
216/

China (adult smoking was 26.6% in 2018)

Of 18 patients who survived, 3 had a history of smoking (16.7%)

Of the 10 patients with with impaired respiratory function when tested ~2 weeks after discharge, 1 had a history of smoking (10%)

ccforum.biomedcentral.com/articles/10.11…
217/

Spain (adult smoking rate was 24% in 2019)

Of 63 patients with active cancer hospitalized due to Covid-19 infection, 11% were current smokers & 43% were former smokers

ejcancer.com/article/S0959-…

Overall respiratory failure & ARDS data in table Image
218/

China (adult smoking was 26.6% in 2018)

Of 105 patients with severe cases who were treated with HFNC oxygen therapy, 10.5% were current or former smokers

researchsquare.com/article/rs-345…
219/

China (adult smoking was 26.6% in 2018)

Of 67 confirmed cases, 5 were current smokers (7.5%)

researchsquare.com/article/rs-342…
220/

China (adult smoking was 26.6% in 2018)

Of 67 hospitalized patients, 3 were current smokers (4.5%) and 2 were former smokers (3.0%)

researchsquare.com/article/rs-161…
221/

Spain (adult smoking rate was 24% in 2019)

Of 564 hospitalized patients, 36% were smokers

Note: not specified if current or ever

papers.ssrn.com/sol3/papers.cf…
222/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 39 patients who had surgery within a few days before or after testing positive, 3 were active smokers (8.8%) & 5 were former smokers (14.7%)

papers.ssrn.com/sol3/papers.cf…
223/

China (adult smoking was 26.6% in 2018)

Of 46 patients, 5 were smokers (10.9%)

Of 21 patients with severe cases, one was a smoker (4.8%)

Note: not specified if current or ever

papers.ssrn.com/sol3/papers.cf…
224/

Iran (cigarette smoking rate was 12% in 2019. Smoking rate including hookah was ~20% in 2019)

Of 105 patients with severe cases, 5.7% were cigarette smokers & 22.9% were hookah users

Note: population smoking prevalence statistics are questionable

papers.ssrn.com/sol3/papers.cf…
225/

Maryland and DC, USA (adult smoking rates were 12.5 & 13.8% in 2019)

Of 832 hospitalized patients, 6.3% were current smokers & 25.8% were former smokers

medrxiv.org/content/10.110…

Outcome data in table Image
226/

USA (adult current smoking rate was 13.7% in 2018)

Of 22 critically-ill patients, 10 had a history of smoking (45.5%)

medrxiv.org/content/10.110…
227/

Michigan, USA (adult smoking rate was 18.9% in 2019)

Of 44 hospitalized patients, 27.3% had a history of smoking

medrxiv.org/content/10.110…
228/

New York City, US (adult smoking rate was 13.4% in 2017)

Of 1,108 patients hospitalized with Covid-19 symptoms, 7.4% were current smokers & 31.2% were former smokers

When those who tested negative were excluded, 5.7% current & 30.4% former (n=965)

medrxiv.org/content/10.110…
229/

China (adult smoking was 26.6% in 2018)

Of 145 patients, 6% were smokers

onlinelibrary.wiley.com/doi/epdf/10.10…
230/

Earth (adult smoking rate was ~20% in 2015)

Of 518 people with rheumatic disease who were diagnosed with Covid-19, 28.8% were ever smokers

Of the 227 of those patients who were hospitalized, 30% were ever smokers

ard.bmj.com/content/early/…
231/

London, UK (adult smoking rate was 13.9% in 2018)

Of 109 cancer patients who tested positive, 10.1% were current smokers & 35.8% were ex-smokers

Of 18 severe cases, 11.1% were current smokers & 44.4% were ex-smokers

medrxiv.org/content/10.110…
232/

Saudi Arabia (adult smoking rate was estimated at 15.4% in 2020)

Of 128 who tested positive, 15.5% were current smokers & 2.3% were former smokers

Note: all mild cases or asymptomatic

medrxiv.org/content/10.110…
233/

London, UK (adult smoking rate was 13.9% in 2018)

Of 16 who died, 1 was a current smoker (6.2%) & 12 were ex-smokers (75%)

Of 15 survivors who recovered after a long time in ICU, zero were current smokers & 10 were ex-smokers (66.7%)

medrxiv.org/content/10.110…
234/

Chicago, USA (adult smoking rate was 16.8% in 2018)

Of 60 critically ill patients, 36.7% were smokers

Note: not specified if current or ever

medrxiv.org/content/10.110…
235/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 174 hospitalized patients, 33.3% were smokers.

Of the 82 of them admitted to ICU, 13.4% were smokers

Note: not specified if current or ever

medrxiv.org/content/10.110…
236/

USA (adult current smoking rate was 13.7% in 2018)

Of 2,489 hospitalized patients, 6.0% were current smokers, 25.8% were former smokers & 68.2 were never smokers or had unknown status

medrxiv.org/content/10.110…
237/

Spain (adult smoking rate was 24% in 2019)

Of 146 hospitalized patients, 6.8% had a history of smoking

Of 71 with critical cases, 8.5% had a history of smoking

medrxiv.org/content/10.110…
238/

Spain (adult smoking rate was 24% in 2019)

Of 4,194 hospitalized patients, 5.5% were active smokers & 19.6% were former smokers

medrxiv.org/content/10.110… Image
239/

North Carolina, USA (adult smoking rate was 17.4% in 2019)

Of 11 patients, 1 was a current cigarette smoker & 1 was a current vaper (9% each)

Shame on the authors for including vaping under "tobacco use"

medrxiv.org/content/10.110…
240/

China (adult smoking rate was 26.6% in 2018)

Of 541 hospitalized patients, 10.5% were current smokers

medrxiv.org/content/10.110…
241/

China (adult smoking rate was 26.6% in 2018)

Of 135 hospitalized patients, 9.6% were smokers

Note: not specified if current or ever

medrxiv.org/content/10.110… Image
242/

Mexico (adult smoking rate was 17.6% in 2016)

Of 569 hospitalized patients, 10.4% were current or past smokers

Of 230 of them who needed critical care, 10.0% were current or past smokers

medrxiv.org/content/10.110…
243/

New York State (adult current smoking rate was 12.8% in 2019)

Of 74 patients with multiple sclerosis or related disorders who received positive diagnoses for Covid-19, 2 were current smokers (2.7%) & 20 were former smokers (27%)

medrxiv.org/content/10.110…
244/

China (adult smoking rate was 26.6% in 2018)

Of 51 severely & critically ill patients, 13.7% were current smokers

Of 12 of them who died, one was a current smoker (8.3%)

medrxiv.org/content/10.110…
245/

Finland (adult current smoking rate was 19% in 2018)

Of 28 hospitalized patients, 3 were current smokers (11%) & 8 were ex-smokers (29%)

Of 7 of them admitted to ICU, 2 were current smokers (29%) & 1 was an ex-smoker (14%)

medrxiv.org/content/10.110…
246/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 40 healthy blood donors who tested positive for SARS-CoV-2 antibodies, 7 were active smokers (17.5%)

Of 749 healthy blood donors who tested negative, 197 were active smokers (27.3%)

medrxiv.org/content/10.110…
247/

New York State (adult current smoking rate was 12.8% in 2019)

Of 54 kidney transplant recipients who were diagnosed with Covid-19, 22% had a history of smoking

Of 39 of them who were hospitalized, 21% had a history of smoking

medrxiv.org/content/10.110…
248/

France (adult daily smoking rate was 27% in 2017)

Of 135 patients (125 hospitalized), 4% were daily smokers & 38% were ex-smokers

Of 10 patients who developed ARDS, all 10 were never smokers

medrxiv.org/content/10.110…
249/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 127 people with multiple myeloma or related disorders who received positive diagnoses, 27% were current or former smokers

medrxiv.org/content/10.110…
250/

France (adult daily smoking rate was 27% in 2017)

Of 55 patients hospitalized with Covid-19, 25.4% had a history of smoking

Of 45 patients hospitalized without Covid-19 during the same period, 42.3% had a history of smoking

researchsquare.com/article/rs-345…
251/

France (adult daily smoking rate was 27% in 2017)

Of 302 cancer patients with suspected cases, 11.6% were current tobacco users & 20.2% were former tobacco users.

Smoking data not disclosed for the 55 patients with confirmed positive diagnoses

continued
251a/

"Present tobacco use...former tobacco use...were not significantly different between the SARS-COV-2 RT-PCR positive and negative subgroups."

ncbi.nlm.nih.gov/pmc/articles/P…
252/

France (adult daily smoking rate was 27% in 2017)

Of 100 people who reported Covid-19 symptoms at an emergency room, 23% were smokers

Of 31 who tested positive, 2 were smokers (6%)

Of 69 who tested negative, 21 were smokers (30%)

onlinelibrary.wiley.com/doi/epdf/10.11…
253/

China (adult smoking rate was 26.6% in 2018)

Of 475 confirmed & suspected cases, 16% had a history of smoking

Of 336 confirmed cases, 16.4% had a history of smoking

onlinelibrary.wiley.com/doi/10.1002/jm…
254/

China (adult smoking rate was 26.6% in 2018)

Of 98 patients recovering from Covid-19, 8 were smokers (8.2%)

Of 17 of them who tested positive during post-discharge quarantine, all 17 were non-smokers

onlinelibrary.wiley.com/doi/10.1002/jc…
255/

Turkey (adult male smoking rate was 44% in 2018)

Of 18 men with enlarged prostates who tested positive, 7 were smokers (38.9%)

onlinelibrary.wiley.com/doi/10.1111/ij…
256/

Countries (adult smoking rate)

France (27% in 2017)
Italy (23.7% in 2016)
Spain (24% in 2019)
Belgium (19.4% in 2018)
Switzerland (27.1% in 2017)

Of 1,420 mild-to-moderate cases, 14.3% were smokers

onlinelibrary.wiley.com/doi/10.1111/jo…

Continued Image
256a/

Notes:

67.7% of patients were female

30.7% were health care workers

Mean age: 39.17

Much overlap with study in tweet 176

257/

New York State (adult current smoking rate was 12.8% in 2019)

Of 3,567 hospitalized patients, 84.4% were never smokers

jamanetwork.com/journals/jama/…
258/

China (adult smoking was 26.6% in 2018)

Of 68 cancer patients with moderate-to-severe cases of Covid-19, 73.5% had a history of smoking

"...we did not find that...smoking history could further increase the mortality risk of patients with cancer"

jhoonline.biomedcentral.com/articles/10.11…
259/

Italy (adult smoking rate was 23.7% in 2016)

Of 102 hospitalized patients, including 16 cancer patients, 7.8% were current smokers & 31.4% were former smokers

journalofinfection.com/article/S0163-…
260/

Sweden (adult daily smoking rate was 10.4% in 2017)

Of 60 hospitalized patients, 8.3% were smokers

Notes:

Not specified if current or ever

Many Swedes are snus users; could complicate results (not mentioned in this paper)

medrxiv.org/content/10.110…
261/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 5,510 confirmed positive patients, 5.0% were current smokers & 23.5% were former smokers

Of 636 deaths, 4.4% were current smokers & 33.6% were former smokers

medrxiv.org/content/10.110…
262/

Thailand (adult smoking rate was 19.9% in 2016)

Contact tracing tests of asymptomatic individuals:

Of 209 positive, 13 reported sharing cigarettes or vaping devices (6.2%)

Of 836 negative, 12 reported sharing cigarettes or vaping devices (1.5%)

medrxiv.org/content/10.110…
263/

France (adult daily smoking rate was 27% in 2017)

There's more in this study than I can tweet. Recommended reading.

medrxiv.org/content/10.110… Image
264/

London, UK (adult smoking rate was 13.9% in 2018)

Of 1,700 hospitalized patients, 10.2% were smokers

Note: not explicitly stated if current or ever. The phrase "smoking history" was used once

medrxiv.org/content/10.110…
265/

Italy (adult female smoking was 19.8% in 2016)

Of 132 infected women who gave birth, zero were current smokers & 10.6% quit before or during pregnancy

Of 43 of them who gave birth with Covid-19 pneumonia, 7% quit before or during pregnancy

medrxiv.org/content/10.110…
266/

China (adult smoking rate was 26.6% in 2018)

Of 262 hospitalized patients, 5.3% were smokers

Of 128 who died, 8.6% were smokers

Note: not specified if current or ever

researchsquare.com/article/rs-347…
267/

Italy (adult smoking rate was 23.7% in 2016)

Of 41 patients who tested positive within days of having surgery, 5 were current smokers within 1 year (12.2%)

Of 82 who didn't test positive, 8 were current smokers within 1 year (9.8%)

jamanetwork.com/journals/jamas…
268/

China (adult smoking rate was 26.6% in 2018)

Of 1,590 hospitalized patients, 7% were former or current smokers

Of 131 of them with critical cases, 13.7% were former or current smokers

Note: mean age was 48.9

jamanetwork.com/journals/jamai…
269/

China (adult smoking rate was 26.6% in 2018)

Of 149 hospitalized patients, 4 were current smokers (2.7%)

Notes:

"the median age of patients was 42 years (range 2-91), and 114 (76.5%) were 21-60 years old"

14 patients were ages 2-20

onlinelibrary.wiley.com/doi/10.1111/tb…
270/

Italy (adult smoking rate was 23.7% in 2016)

Of 355 people with confirmed diagnoses, 13.5% were smokers

Note: not specified if current or ever

onlinelibrary.wiley.com/doi/10.1002/he…
271/

Another one which contains more than I can tweet:

National Smoking Rates Correlate Inversely with COVID-19 Mortality

medrxiv.org/content/10.110…
272/

Washington State, USA (Adult smoking rate was 12% in 2019)

Of 111 hospitalized patients, 10.8% were current smokers & 6.3% were former smokers

heartrhythmopen.com/article/S2666-…
273/

Of 14 Italian tourists treated at a hospital in Gurgaon, India, 3 were smokers (21.43%)

Adult smoking rates in 2016-17:

Haryana 19.7% in 2016-17
Delhi 11.3% in 2016-17
Italy: 23.7% in 2016

Notes:

not stated if current or ever

ages 45-80

sciencedirect.com/science/articl…
274/

China (adult smoking rate was 26.6% in 2018)

Of 1,449 hospitalized patients, 5.7% had a history of smoking

Of 122 of them who died, 13.9% had a history of smoking

nature.com/articles/s4137…
275/

Turkey (adult smoking rate was 27.2% in 2016)

Of 64 symptomatic individuals who tested positive, 14 were smokers (21.9%)

Notes:

not specified if current or ever

60.9% of sample was female

mean age was 37.78

journals.sagepub.com/doi/10.1177/01…
276/

France (adult female smoking rate was 22.9% in 2018)

Of 88 pregnant women who tested positive, 3 were smokers (3.4%)

Note: women are advised to refrain from smoking during pregnancy

ejog.org/article/S0301-…
277/

China (adult smoking rate was 26.6% in 2018)

Of 1,004 hospitalized patients, 46% were smokers

Of 40 of them who died, 55% were smokers

Note: not specified if current or ever

onlinelibrary.wiley.com/doi/full/10.10…
278/

New York City, USA (2017 smoking rate was 13.4%)

Past or present smoking in hospitalized adults:

572 age ≤50: 13.3%
2,834 age >50: 25.3%

Past or present smoking deaths

60 ≤50: 21.7%
1,076 >50: 26.8%

Note:

≤50: 69.4% male
>50: 55.2% male

onlinelibrary.wiley.com/doi/abs/10.100…
279/

Italy (adult male smoking rate was 28.3% in 2015)

Of 31 men in respiratory ICU, one was a current smoker (3.2%) & 11 were former smokers (35.5%)

onlinelibrary.wiley.com/doi/full/10.11…
280/

China (adult smoking rate was 26.6% in 2018)

Of 80 patients, 8 were smokers (10%)

Of 69 of them with severe cases, 8 were smokers (11.59%)

Note: median age of severe patients was 56 & median age for non-severe patients was 31

embopress.org/doi/full/10.15…
281/

China (adult smoking rate was 26.6% in 2018)

Of 130 patients, 11.5% were current smokers

Note: not a completely random sample; half of patients had metabolic associated fatty liver disease.

Current smokers
Without MAFLD: 16.9%
With MAFLD: 6.2%

onlinelibrary.wiley.com/doi/full/10.11…
282/

Italy (adult smoking rate was 23.7% in 2016)

Of 50 patients with cirrhosis with confirmed diagnoses of Covid-19, 20 were current or former tobacco smokers (40%)

Smoking history was not significantly associated with 30-day mortality

journal-of-hepatology.eu/article/S0168-…
283/

China (adult smoking rate was 26.6% in 2018)

Of 1,875 hospitalized patients, 7.8% were smokers

Of 50 of them with a history of stroke, 16% were smokers

Note: not explicitly specified if current or ever, but the term "smoking history" is used once

ahajournals.org/doi/10.1161/ST…
284/

Hong Kong (adult smoking rate was 10% in 2017)

Of 9 adult Hong Kong residents who tested positive on their return to Hong Kong after being quarantined on the Diamond Princess, 1 was a smoker (11%)

Of 206 who tested negative, 18 were smokers (9%)

thelancet.com/journals/lanin…
285/

Earth (adult smoking rate was ~20% in 2015)

Of 196 patients with thoracic cancer & a positive Covid-19 diagnosis, 24% were current smokers & 57% were former smokers

Of 148 of them who were hospitalized, 26% were current smokers & 57% were former smokers

Continued
285a/

Notes:

94% of patients had lung cancer

Patients from Italy, Spain, France, Switzerland, Netherlands, USA, UK, and China

thelancet.com/journals/lanon…
286/

Of 104 Diamond Princess passengers/crew hospitalized in Japan after testing positive, 17% were current smokers

Patient nationality:
53% East Asian
20% Southeast Asian
27% other

Note: 41% of patients were asymptomatic

thelancet.com/journals/lanin…
287/

China (adult smoking rate was 26.6% in 2018)

Of 155 individuals with confirmed diagnoses, 12.9% had a history of smoking

authorea.com/users/333698/a…
288/

China (adult smoking rate was 26.6% in 2018)

Of 271 patients with severe cases, 37.3% were smokers

Of 22 deaths, 13 were smokers (59.1%)

Note: not specified if current or ever

researchsquare.com/article/rs-351…
289/

France (daily smoking rate was 27% in 2017)

Of 702 individuals who had transcatheter aortic valve replacement between 2010 & 2019, 3.7% were current smokers (when?)

Of 22 of them who had confirmed cases of Covid-19, one was a current smoker (4.5%)

medrxiv.org/content/10.110…
290/

Israel (adult smoking rate was 19.1% in 2018)

Of 145 hospitalized patients, 12.4% were current smokers

medrxiv.org/content/10.110…
291/

China (adult smoking rate was 26.6% in 2018)

Of 88 ICU patients, 10.2% had a history of smoking*

Of 64 of them who died within 14 days, 9.4% had a history of smoking

*There is a error in the count. Might be 11.4%.

authorea.com/users/333981/a…
292/

China (adult smoking rate was 26.6% in 2018)

Of 788 hospitalized patients, 6.9% were current smokers

journals.lww.com/ajg/Abstract/9…
293/

Jordan (adult smoking rate was 41.0% in 2015)

Of 88 cases, 32.1% were cigarette smokers

Notes:

population smoking statistics are questionable

waterpipe use may complicate results

mean age: 40

only 1 patient died: a woman (age 80) with cancer

sciencedirect.com/science/articl…
294/

Chile (adult smoking rate was 38% in 2015)

Of 21 hospitalized patients, 2 were previous or current tobacco smokers (9.5%)

Note: 76.2% of patients were female (female smoking rate in 2015 was 36%)

medrxiv.org/content/10.110…
295/

China (adult smoking rate was 26.6% in 2018)

Of 57 patients studied 30 days after discharge from a hospital, 15.7% had a history of smoking

researchsquare.com/article/rs-264…
296/

Netherlands (adult cigarette smoking rate was 22.4% in 2018)

Of 32 patients considered too frail for mechanical ventilation & given HFNC treatment instead, 15.6% were current smokers & 18.8% were former smokers

Continued
296a/

Of 24 of them who died, 16.7% were current smokers & 20.8% were former smokers

Note: ages 72.5 to 84.3

researchsquare.com/article/rs-344…
297/

Victoria, Australia (adult daily smoking rate was 12.8% in 2016)

Of 424 people tested, 45% were smokers

Of 14 who tested positive, 64% were smokers

Note: not stated if current or ever

onlinelibrary.wiley.com/doi/10.1111/17…
298/

China (adult smoking rate was 26.6% in 2018)

Of 1,031 hospitalized patients, 10.1% were smokers

Of 165 of them who died, 21.8% were smokers

Note: not explicitly stated if current or ever, but the term "smoking history" is used once

medrxiv.org/content/10.110…
299/

Earth (adult smoking rate was ~20% in 2015)

Of 9,358 patients ages 50 & under with confirmed diagnoses, 5.9% had "nicotine dependence"

Of 64 of them who had an acute ischemic stroke, 34.4% of them had "nicotine dependence"

ajconline.org/article/S0002-…
300/

Norway (adult daily smoking rate was 9% in 2019. Daily & non-daily smoking was 20.2% in 2016)

Of 58 hospitalized patients, 31% were current or former smokers

Of 15 severe cases, 26.7% were current or former smokers

Note: snus use may complicate

researchsquare.com/article/rs-308…
301/

Germany (smoking rate 25% in 2017)

Of 26 infected patients who died, 3 were active smokers (10.5%)

Autopsies showed multiple comorbidities in all patients, more than stated in medical records. 7 had emphysema (26.9%), including 1 of the 3 smokers

medrxiv.org/content/10.110…
302/

USA (adult current smoking rate was 13.7% in 2018)

Of 333 hospitalized patients, 7.6% were current smokers & 40.5% were former smokers

link.springer.com/article/10.100…
303/

China (adult smoking rate was 26.6% in 2018)

Of 1,859 hospitalized patients, 2.4% were current smokers & 3.6% were former smokers

Of 208 of them who died, 6.3% were current smokers & 5.8% were former smokers

Continued
303a/

Note: "Smoking history was defined as current or former smoker (stopping >5 years ago) with exposure of ≥20 cigarettes per day for ≥1 year (1 pack year)."

nature.com/articles/s4137…
304/

Indiana, USA (adult current smoking rate was 21.1% in 2019)

Of 2,953 tested asymptomatic individuals, 3.9% were current smokers & 24.2% were former smokers

Of 91 of them who tested positive, 1.1% was a current smoker & 25.3% were former smokers

onlinelibrary.wiley.com/doi/10.1002/jm…
305/

China (adult smoking rate was 26.6% in 2018)

Of 856 hospitalized patients, 7.0% were current smokers

onlinelibrary.wiley.com/doi/epdf/10.10…
306/

China (adult smoking rate was 26.6% in 2018)

Of 51 hospitalized patients, 37.3% had a history of smoking

onlinelibrary.wiley.com/doi/epdf/10.11…
307/

Michigan, USA (adult smoking rate was 18.9% in 2019)

Of 463 patients, 34.8% were tobacco users (TUs)

Of 355 hospitalized, 38.6% were TUs

Of 141 in ICU, 41.1% were TUs

Notes:

72.1% of patients were African American

not stated if current or ever

jamanetwork.com/journals/jaman…
308/

London, UK (adult smoking rate was 13.9% in 2018)

Of 51 surviving patients with troponin elevation, 25.5% had a history of smoking

Notes

80.4% male

patients age 80+ were excluded

papers.ssrn.com/sol3/papers.cf…
309/

New Jersey, USA (adult smoking rate was 13.1% in 2019)

Of 20 Covid-19 patients who had an acute ischemic stroke, 5 had a history of smoking (25%)

papers.ssrn.com/sol3/papers.cf…
310/

UK (adult smoking rate was 14.7% in 2018)

Updated numbers from same dataset as study in tweet 85

Of 20,246 hospitalized patients, 7.1% were current smokers & 34.2% were former smokers

papers.ssrn.com/sol3/papers.cf…

311/

Iran

120 hospitalized patients: age and sex matched groups of smokers & non smokers

"Current findings showed that the clinical picture of smoker and non-smoker COVID-19 patients does not differ significantly."

researchsquare.com/article/rs-342…
312/

Texas, USA (adult smoking rate was 14.4% in 2019)

Of 147 hospitalized patients, 14.3% were active smokers

medrxiv.org/content/10.110…
313/

Michigan, USA (adult smoking rate was 18.9% in 2019)

Of 4,699 tested, 8.5% were current smokers (CS) & 29.9% were past smokers (PS)

Of 884 who tested positive, CS=4.5% & PS=29.9%

Of 373 hospitalized, CS=2.7% & PS=37%

Of 134 in ICU, CS=2.2% & PS=45.5%

Continued
313a/

Of 20 who died, CS=zero & PS=70%

Notes:

6.6% of tested were age 18 or less
0.8% of positive were 18 or less

38% of tested were male
56.5% of hospitalized were male

2019 MI female smoking rate was 16.9%
2019 MI male smoking rate was 21.1%

medrxiv.org/content/10.110…
314/

Spain (adult smoking rate was 24% in 2019)

Of 25 hospitalized patients, 2 were current smokers (8%) and zero were former smokers

preprints.org/manuscript/202…
315/

China (smoking rate was 26.6% in 2018)

Of 1,690 hospitalized patients with non-critical cases, 13.6% had a history of smoking

Of 697 critical patients, 19.7% had a history of smoking

2nd group included 346 from 1st group whose illness progressed

drc.bmj.com/content/8/1/e0…
316/

France (adult daily smoking rate was 27% in 2017)

All patients assessed at one hospital

Of 70 adults infected with SARS-CoV-2, 14.3% were current smokers

Of 54 adults infected with influenza during the same time period, 20.4% were current smokers

sciencedirect.com/science/articl…
317/

France (adult daily smoking rate was 27% in 2017)

Of 15 ICU patients, 2 were smokers (13.3%)

Notes:

ages 60-72
80% of patients were male

medrxiv.org/content/10.110…
318/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 204 hospitalized patients, 35.3% had a history of smoking

Note: patients who were "intubated, receiving noninvasive ventilatory assistance, or deceased" were excluded

jamanetwork.com/journals/jamao…
319/

Georgia, USA (adult smoking was 16.1% in 2019)

Of 259 nonhospitalized patients, 14.3% were past or current smokers (PCS)

Of 211 hospitalized patients, 25.6% were PCS

cdc.gov/mmwr/volumes/6…

Note: hospitalized patients were "selected" from 👇

320/

France (adult daily smoking rate was 27% in 2017)

Of 4,486 hospitalized patients, 25.8% were current smokers

Note; "Co-morbidities and risk factors...were recorded for the two-year period before the index date"

medrxiv.org/content/10.110…
321/

Spain (adult smoking rate was 24% in 2019)

Of 125 pregnant women who tested positive, 8.0% were smokers

1st trimester: 7.4%
3rd trimester: 8.5%

Notes:

Not specified if current or ever
Pregnant women are encouraged to refrain from smoking

medrxiv.org/content/10.110…
322/

England, UK (adult smoking rate was 14.4% in 2018)

Of 251,440 people with T1 diabetes, 17.3% were current smokers (CS) & 24.6% were ex-smokers (XS)

Of 418 of them who died with Covid-19, CS=8.4% & XS=37.8%

papers.ssrn.com/sol3/papers.cf…

Continued
322a/

Of 2,886,740 people with T2 diabetes, CS=12.8% & XS=35.1%

Of 9,362 of them who died with Covid-19, CS=5.2% & XS=42.8%

Note: ~2% of sample was classified "non-smoker" because they did not currently smoke, but it was unknown whether they had formerly. I included with never
323/

China (adult smoking rate was 26.6% in 2018)

Of 370 survivors, 5.7% were current smokers

Of 50 of them who reported post-discharge anxiety, 4.0% were current smokers

Of 40 of them who reported post-discharge depression, 2.5% were current smokers

onlinelibrary.wiley.com/doi/full/10.10…
324/

London, UK (adult smoking rate was 13.9% in 2018)

Of 204 hospitalized patients, 43.1% had a history of smoking

Of 54 who died, 51.9% had a history of smoking

journalofinfection.com/article/S0163-…
325/

Turkey (adult smoking rate was 27.2% in 2016)

Of 29 genetically related patients hospitalized with confirmed Covid-19, 37.9% had a history of smoking

Of an age and sex matched group (n=52) admitted to the same hospital, 23.1% had a smoking history

onlinelibrary.wiley.com/doi/abs/10.100…
326/

Italy (adult smoking rate was 23.7% in 2016)

Of 51 hospitalized (non-intubated) patients who required oxygen or CPAP:

1 was an active smoker (2%)
1 was a former smoker for less than a year (2%)
20 were former smokers for more than a year (39.2%)

thelancet.com/journals/lanre…
327/

India (adult smoking rate was 10.7% & smokeless tobacco use was 21.4% in 2016-17)

Of 109 patients with confirmed diagnoses, 3.6% had a history of smoking & 5.5% were tobacco users

papers.ssrn.com/sol3/papers.cf…

Continued
327a/

Notes:

Mean age was 38.4

86.2% of patients were male (male smoking rate was 19% & smokeless use was 29.6% in 2016-17)

Intubated & very sick patients were excluded (number unstated)

Patients were hospitalized April 1-20. The government banned tobacco sales on April 15
328/

China (adult smoking rate was 26.6% in 2018)

Of 363 severe & critical cases, 7.2% were smokers

159 severe: 3.1% were smokers
204 critical: 10.3% were smokers

Of 152 of them who died, 11.2% were smokers

Note: not specified if current or ever

papers.ssrn.com/sol3/papers.cf…
329/

New York, USA

102 lung cancer patients who tested positive for SARS-CoV-2

Number of smokers & non-smokers not reported.

Only 27 of them had a smoking history equal to or greater than 5 pack-years (26.47%, which the authors rounded up to 27%)

sciencedirect.com/science/articl…
330/

USA (adult current smoking rate was 13.7% in 2018)

Of 6,256 patients with obesity or T2 diabetes hospitalized for Covid-19, 13 were tobacco users (0.2%)

medrxiv.org/content/10.110…
331/

Italy (adult smoking rate was 23.7% in 2016)

Of 173 patients with severe Covid-19 pneumonia, 29.5% were ever smokers

medrxiv.org/content/10.110…
332/

London, UK (adult smoking rate was 13.9% in 2018)

Of 6,215 people with schizophrenia-spectrum disorders, 67.3% were current smokers (CS) & 27.2% were past smokers (PS)

Of 100 of them who tested positive, CS=78 & PS=20

medrxiv.org/content/10.110…

Note: see methods 👇 Image
333/

Spain (adult smoking rate was 24% in 2019)

Of 260 who tested positive, 31.2% were current or ex-smokers

Of 141 hospitalized, 35.5% were current or ex-smokers

Of 48 deaths or ICU admissions, 43.8% were current or ex-smokers

medrxiv.org/content/10.110…
334/

New York State (adult current smoking rate was 12.8% in 2019)

Of 32 critically ill patients, 50% were current or former smokers

medrxiv.org/content/10.110…
335/

China (adult smoking rate was 26.6% in 2018)

Of 616 patients hospitalized with confirmed Covid-19, 3.8% were smokers

Of 35 patients hospitalized with suspected Covid-19 who tested negative for antibodies, 5.7% were smokers

medrxiv.org/content/10.110…
336/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 407 hospitalized African Americans, 8.8% were active smokers

Of 132 of them who died, 6.1% were active smokers

papers.ssrn.com/sol3/papers.cf…
337/

China (adult smoking rate was 26.6% in 2018)

Of 105 patients with confirmed or suspected cases, 43.8% were current smokers

Of the 21 who had confirmed cases, 52.4% were current smokers

atm.amegroups.com/article/view/4…
338/

China (adult smoking rate was 26.6% in 2018)

Of 80 hospitalized patients, 6.3% had a history of smoking

Of 27 of them with severe cases, 14.8% had a history of smoking

journals.plos.org/plosone/articl…
339/

China (adult smoking rate was 26.6% in 2018)

Of 97 hospitalized patients, 20.6% were current smokers & 12.4% were former smokers

Of 12 of them with severe cases, 5 were current smokers (41.7%) & 1 was a former smoker (8.3%)

onlinelibrary.wiley.com/doi/10.1111/al…
340/

Ontario, Canada (current smoking rate age 12 and over was 15.2% in 2017)

Of 21,922 confirmed cases, 2.4% were smokers

medrxiv.org/content/10.110…
341/

Chicago, USA (adult smoking rate was 16.8% in 2018)

Of 103 recovered patients who donated plasma, 25.2% were past or current smokers

medrxiv.org/content/10.110…
342/

Germany (adult smoking rate was 25% in 2017)

Of 126 symptomatic patients who were tested at an emergency department, 30.2% were current smokers & 24.6% had quit

Of 13 of them who tested positive, 7.7% was a current smoker & 23.1% had quit

researchsquare.com/article/rs-370…
343/

China (adult smoking rate was 26.6% in 2018)

Of 200 hospitalized patients, 3.5% were current smokers

researchsquare.com/article/rs-354…
344/

China (adult smoking rate was 26.6% in 2018)

Of 136 hospitalized patients, 11 had a history of smoking (8.1%)

Of 16 of them with severe cases, 1 had a history of smoking (6.3%)

researchsquare.com/article/rs-350…
345/

China (adult smoking rate was 26.6% in 2018)

Of 544 hospitalized patients, 7.5% were current smokers & 9.4% were former smokers

Of 265 of them with severe cases, 6.8% were current smokers & 12.5% were former smokers

sciencedirect.com/science/articl…
346/

Italy (adult smoking rate was 23.7% in 2016)

Of 26 patients with asthma hospitalized with Covid-19, 14 were current smokers (53.8%)

jacionline.org/article/S0091-…
347/

Italy (adult smoking rate was 23.7% in 2016)

Of 62 hospitalized patients, 35.5% were current smokers

papers.ssrn.com/sol3/papers.cf…
348/

Turkey (adult smoking rate was 27.2% in 2016)

Of 113 patients with hypertension who were hospitalized with Covid-19, 8.0% were smokers

Of 35 of them who died, 11.4% were smokers

tandfonline.com/doi/full/10.10…
349/

Italy (adult smoking rate was 23.7% in 2016)

Of 23 ICU patients who had a tracheostomy, 4 were current smokers (17.4%)

Notes:

91% of patients were male
mean age was 69 (42-84)

researchsquare.com/article/rs-364…
350/

Turkey (adult smoking rate was 27.2% in 2016)

Of 172 people who tested positive, 23.8% had a history of smoking

Note: most had mild or moderate symptoms

sciencedirect.com/science/articl…
351/

Spain (adult smoking rate was 24% in 2019)

Of 31 confirmed & 10 suspected cases in people with rheumatic diseases, 9.8% were current smokers & 24.4% were former smokers

Notes:

61% female
28/41 hospitalized
3 deaths: 1 CS, 1 FS, 1 NS

ard.bmj.com/content/79/7/9…
352/

Earth (adult smoking rate was ~20% in 2015)

Of 518 people with rheumatic diseases diagnosed with Covid-19, 24.9% were ever smokers

Of 227 of them hospitalized, 30% were ever smokers

Notes:

75% female
40 countries: N America: 57%, Eur: 36%

ard.bmj.com/content/79/7/8…
353/

China (adult smoking rate was 26.6% in 2018)

Of 67 hospitalized patients, 3 were current smokers (4.5%) & 2 were former smokers (3.0%)

bmcmedimaging.biomedcentral.com/articles/10.11…
354/

China (2018 smoking rate was 26.6%)

Of 105 cancer patients hospitalized with Covid-19, 34.3% were smokers

Of 536 hospitalized patients without cancer, 8.6% were smokers

Note: not clear if current or ever. The term "smoking history" was used once

cancerdiscovery.aacrjournals.org/content/10/6/7…
355/

Ontario, Canada (current smoking rate age 12+ was 15.2% in 2017)

Of 127 people who were tested, 9.5% were current smokers (CS) & 21.3% were ex-smokers (XS)

Of 56 who tested positive, 5.4% were CS & 19.6% were XS

2 vapers (1.6%) tested: both positive (3.6%)

Continued
355a/

Notes:

median age 41.0 (32.0-52.5)

58.9% of positives were female

4 patients were hospitalized

In Canada, past 30 day vaping rate ages 25+ was 3% in 2019 (over half of them daily)

cambridge.org/core/journals/…
356/

Italy (adult smoking rate was 23.7% in 2016)

Of 59 patients with moderate symptoms, 18.7% were current smokers

care.diabetesjournals.org/content/43/7/1…
357/

France (adult daily smoking rate was 27% in 2017)

Of 50 positive diagnoses, 10% were active smokers (AS) & 18% were former smokers (FS)

12 no/mild pneumonia: AS 8%, FS 17%

17 moderate: AS 18%, FS 18%

16 severe: AS 6%, FS 25%

erj.ersjournals.com/content/early/…
358/

England, UK (adult smoking rate was 14.4% in 2018)

Of 215 hospitalized patients, 55.8% had a history of smoking

Of 86 of them who died, 63.9% had a history of smoking

researchsquare.com/article/rs-357…
359/

China (adult smoking rate was 26.6% in 2018)

Of 67 patients who had a diagnosis of cancer & also a diagnosis of Covid-19, 13.4% had a history of smoking

Of 32 of them with severe cases, 15.6% had a history of smoking

acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…
360/

Earth (adult smoking rate was ~20% in 2015)

Update

Of 1,572 positive diagnoses in people with inflammatory bowel disease in 40+ countries, 4.5% were current smokers (CS)

Of 455 hospitalized patients, CS = 6.4%

Of 85 admitted to ICU, CS = 4.7%

360a/

Of 69 who needed mechanical ventilation, CS = 2.9%

Of 51 who died, CS = 7.8%

Note: smoking among people with IBD may differ from general population

covidibd.org/current-data/

361/

China (adult smoking rate was 26.6% in 2018)

Of 307 confirmed cases, 8.8% were current smokers (CS)

Of 20 mild cases, CS=5%

Of 249 moderate cases, CS=8.8%

Of 38 severe cases, CS=10.5%

academic.oup.com/nsr/article/do…
362/

Los Angeles, USA (adult smoking rate in LA County was 11% in 2015-17)

Of 27 patients who were on mechanical ventilation (21) or oxygen through nasal cannula (6), zero were current smokers & 3 were former smokers (11%)

Notes:

85% were male

academic.oup.com/cid/article/do…
363/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 193 patients with severe to critical cases, two were active smokers (1%)

academic.oup.com/qjmed/article/…
364/

Spain (adult smoking rate was 24% in 2019)

Of 160 hospitalized patients ages 35 to 65, 19.3% were current or previous smokers

academic.oup.com/jid/article/do…
365/

France (adult daily smoking rate was 27% in 2017)

Of 54 ICU patients (including 49 who were mechanically ventilated), 5 were tobacco users (9.3%)

Of 20 of them who acquired ventilator-associated pneumonia 1 was a tobacco user (5%)

academic.oup.com/cid/article/do…
366/

Italy (adult smoking rate was 23.7% in 2016)

Of 26 patients with severe asthma who had confirmed or highly suspected Covid-19, 3 were smokers (11.5%) & 4 were ex/former smokers (15.4%)

The 2 who died were never smokers

authorea.com/users/335384/a…
367/

France (adult daily smoking rate was 27% in 2017)

Of 610 cancer patients, 115 were current smokers (18.9%)

Of 9 of them who tested positive, one was a current smoker (11.1%)

Note: thoracic (including lung) & hematological cancer patients excluded

onlinelibrary.wiley.com/doi/10.1002/ij…
368/

Georgia, USA (adult smoking rate was 16.1% in 2019)

Of 470 patients, 19.4% were past or current smokers (PCS)

Of 211 of them who were hospitalized, PCS=25.6%

cdc.gov/mmwr/volumes/6…

There appears to be significant overlap with study in tweet 11

369/

Iran (cigarette smoking was 12% in 2019. Smoking including hookah was ~20% in 2019)

Of 117 patients with COVID-19 and T2 diabetes, 6.0% were smokers

"Individuals who had ceased smoking more than 10 years earlier were considered as non-smokers"

diabetesresearchclinicalpractice.com/article/S0168-…
370/

Ohio, Kentucky & Indiana, USA (adult current smoking rates were 20.5%, 23.4% & 21.1% in 2019)

Of 532 diagnoses, 32% were past or current smokers

Of 164 hospitalized, 46.3% were past or current smokers

Note: Cincinnati metro area

medrxiv.org/content/10.110…
371/

Thailand (adult smoking rate was 19.9% in 2016)

Of 157 confirmed cases, 18.5% were ever smokers (ES)

Of 9 asymptomatic, ES=11%
Of 82 mild cases, ES=19.5%
Of 40 moderate, ES=20%
Of 22 severe, ES=13.6%
Of 4 critical, ES=25%

medrxiv.org/content/10.110…
372/

Italy (adult smoking rate was 23.7% in 2016)

Of 312 hospitalized patients, 17.3% were current smokers

Of 91 of them who died, 26.4% were current smokers

researchsquare.com/article/rs-379…
373/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 200 expired patients, 9.5% were known current or former smokers

Note: "Past medical history (including comorbidities...based on documentation in the admission profile..."

researchsquare.com/article/rs-378…
374/

China (adult smoking rate was 26.6% in 2018)

Of 1,087 hospitalized patients, 85% were former and/or current smokers

Of 97 of them admitted to ICU, 77.3% were former and/or current smokers

Note: 51.7% of patients were female

researchsquare.com/article/rs-369…
375/

China (adult smoking rate was 26.6% in 2018)

Of 109 hospitalized patients, 9 were current smokers (8.3%)

Of 48 of them whose hospital stay was longer than 10 days, one was a current smoker (2.1%)

Note: no deaths

researchsquare.com/article/rs-349…
376/

China (adult smoking rate was 26.6% in 2018)

Of 415 patients, 21 had a history of smoking (5.1%)

Of 29 of them with severe cases, 3 had a history of smoking (10.3%)

Note: median age 44 (30-61)

researchsquare.com/article/rs-349…
377/

France (adult daily smoking rate was 27% in 2017)

Of 268 hospitalized patients, 3.4% were current smokers & 16.4% were former smokers

Of 69 admitted to ICU, CS=4.3% & FS=23.2%

Of 47 who died before ICU admission, CS=4.3% & FS=8.5%

academic.oup.com/ehjcvp/article…
378/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 116 patients who had a lower extremity venous duplex scan & were SARS-CoV-2 positive, 16.4% were current smokers & 17.2% were former smokers

sciencedirect.com/science/articl…
379/

Massachusetts, USA (adult smoking rate was 13.4% in 2019)

Of 39 patients who received inhaled nitric oxide therapy for Covid-19, 12 were active or prior smokers (30.8%)

journals.sagepub.com/doi/10.1177/17…
380/

France (adult daily smoking rate was 27% in 2017)

Of 347 patients with multiple sclerosis & a confirmed or highly suspected diagnosis of COVID-19, 9.5% were smokers

Notes:

71.8% of patients were female
not specified if current or ever

jamanetwork.com/journals/jaman…
381/

China (adult smoking rate was 26.6% in 2018)

Of 95 hospitalized patients, 6.3% were current smokers

gut.bmj.com/content/69/6/9…
382/

Greece (adult smoking rate was 27.1% in 2017)

Of 93 hospitalized patients, 6.5% were current smokers & 32.3% were former smokers

jamanetwork.com/journals/jaman…
383/

Brazil (adult daily smoking rate was 15.4% in 2015)

Of 8,273 patients diagnosed with Covid-19, 1.7% were smokers

Of 607 of them who died, 7.7% were smokers

Notes:

Over 96% of cases were laboratory confirmed
3.2% of patients were <age 20 (1 died)

medrxiv.org/content/10.110…
384/

Brazil (adult daily smoking rate was 15.4% in 2015)

Of 109 SARS-CoV-2 positive patients with cancer who were hospitalized for any reason, 16.5% were current smokers & 20.2% were former smokers

Notes:

60.8% were female
3.9% had lung cancer

medrxiv.org/content/10.110…
385/

Finland (adult smoking rate was 19% in 2018)

Of 28 Covid-19 patients hospitalized with severe acute respiratory infection, 3.6% was a current smoker (CS) & 32.1% were ex-smokers (XS)

Of 33 influenza pts. hospitalized with SARI, CS=30.3% & XS=24.2%

medrxiv.org/content/10.110…
386/

Chicago, USA (adult smoking rate was 16.8% in 2018)

Of 664 patients, 25.8% were past or current tobacco users (PCTU)

Of 348 of them who were hospitalized, PCTU=32.8%

Of 44 who died, PCTU=52.3%

Note: 86.5% of patients were African American

medrxiv.org/content/10.110…
387/

Cameroon

Of 51 Covid-19 patients with mild symptoms, 2 were tobacco consumers (3.9%)

Note: Cameroon population tobacco prevalence statistics vary widely depending on source. All of them are much more than 3.9%

medrxiv.org/content/10.110…
388/

Mexico (adult smoking rate was 17.6% in 2016)

Updated numbers as of Jun 3

Of 101,238 cases, 8.2% were smokers

Of 80,434 cases age <60, 8.1% were smokers

Of 20,804 cases age ≥60, 8.7% were smokers

academic.oup.com/biomedgerontol…
389/

China (adult smoking rate was 26.6% in 2018)

Of 342 hospitalized patients, 3.5% were smokers

Note: not specified if current or ever

researchsquare.com/article/rs-375…
390/

Kuwait (adult smoking rate was 22.5% in 2015)

Of 1,123 hospitalized patients, 3.9% were current smokers (CS)

294 Kuwaiti: CS=4.4% (52.4% male)
829 non-Kuwaiti: CS=3.7% (91.6% male)

researchsquare.com/article/rs-377…

Many pts included in study in tweet 23

391/

China (adult smoking rate was 26.6% in 2018)

Of 1,188 hospitalized patients, 8.1% were current smokers & 16.8% were ever smokers

Note: total number for smoking status (1,188) is greater than total number of patients (1,184)

papers.ssrn.com/sol3/papers.cf…
392/

Mexico (adult smoking rate was 17.6% in 2016)

Of 16,752 patients, 8.9% were smokers

Of 1,569 deaths, 9.62% were smokers

Note: Other data in this thread are more up-to-date than this

researchsquare.com/article/rs-390…
Just noticed something:

In this study, the number of patients with and without smoking histories exceeds the total number of patients.

393/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 234 hospitalized patients, 86.75% were smokers

Notes:

70.1% of patients were female
not specified if current or ever

researchsquare.com/article/rs-384…
394/

Mexico (tobacco use rate age 20+ was 11.4% in 2018)*

Of 740 patients with confirmed cases, 10.8% were current tobacco users

Of 207 of them with severe symptoms, 15.6% were current tobacco users

*see note in next tweet

medrxiv.org/content/10.110…
394a/

The authors of the study in the previous tweet cited INSP data which stated:

"In 2012, the percentage of tobacco use among the population aged 20 and over was 19.9%, and in 2018 it fell to 11.4 percent."

ensanut.insp.mx/encuestas/ensa…
395/

China (adult smoking rate was 26.6% in 2018)

Of 96 patients with confirmed SARS-CoV-2 infections, 8 were tobacco smokers (8.3%)

idpjournal.biomedcentral.com/articles/10.11…
396/

Earth (adult smoking rate was ~20% in 2015)

Of 758 patients with confirmed or highly-suspected Covid-19, 21.6% were smokers

Notes:

not clear which countries
not specified if current or ever

link.springer.com/article/10.100…
397/

China (adult smoking rate was 26.6% in 2018)

Of 57 patients, 15.8% had a history of smoking

respiratory-research.biomedcentral.com/articles/10.11…
A second look at the study in tweet 331 showed that I probably misreported its results. Apparently there was some missing data. Most likely it is:

Of 138 patients with severe Covid-19 pneumonia, 40% were ever smokers

398/

Brazil (adult daily smoking rate was 15.4% in 2015)

Of 32 patients with critical or severe cases, 8 had a history of smoking (25%)

Note: not reported in what country patients were afaict

medrxiv.org/content/10.110…
399/

Mexico

Other data in this thread are more up-to-date. Adding for the record

sciencedirect.com/science/articl…
400/

Also for the record:

All studies using UK Biobank data were excluded because smoking status data date from 2006 to 2010.
401/

Mexico (adult female smoking rate was 9.3% in 2017)

Of 224 pregnant women with confirmed Covid-19, 3.1% were smokers

Of 7 who died, zero were smokers

Note: women are advised not to smoke during pregnancy

medrxiv.org/content/10.110…
402/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 11,116 suspected cases, 26.8% were past or current smokers (PCS)

Of 6,393 of them who tested positive, PCS=25.7%

Of 484 intubated, PCS=27.7%

Of 618 deaths, PCS=33.7%

medrxiv.org/content/10.110…
403/

Iran (adult cigarette smoking rate was 12% in 2019. Adult smoking rate including hookah was ~20% in 2019)

Of 54 Covid-19 outpatients, one was a current smoker (1.9%)

Note: Iran population smoking prevalence statistics are questionable

onlinelibrary.wiley.com/doi/10.1111/ij…
404/

China (adult smoking rate was 26.6% in 2018)

Of 65 hospitalized patients ages 18-40 with moderate (53) or severe (12) symptoms, one was a cigarette smoker (1.5%)

The smoker was in the severe group

onlinelibrary.wiley.com/doi/10.1002/ob…
405/

Victoria, Australia (adult daily smoking rate was 12.8% in 2016)

Of 2,935 people tested for SARS-CoV-2, 259 were smokers (8.8%)

Of 108 of them who tested positive, three were smokers (2.8%)

medrxiv.org/content/10.110…
406/

Philadelphia, USA (adult current smoking rate was 18-19% in 2017)

Of 129 patients who had high flow nasal therapy, 37.2% were current smokers

Of 40 of them who were intubated, 55% were current smokers

medrxiv.org/content/10.110…

See note in next tweet
406a/

All 3 studies from Philadelphia so far occurred at the same hospital with the same starting date & had the same lead author.

The others:

1.

2.
407/

Iran (adult cigarette smoking rate was 12% in 2019. Adult smoking rate including hookah was ~20% in 2019)

Of 66 EMTs with confirmed cases, 97% were smokers

Of 148 healthy EMTs, 86.5% were smokers

Notes:

all male
not stated if current or ever

researchsquare.com/article/rs-392…
408/

Milan, Italy (adult smoking rate was 19% in 2017)

Of 199 people admitted to a hospital emergency department with symptoms, 12 were active smokers (6%)

Of 124 of them who tested positive, 4 were active smokers (3.2%)

researchsquare.com/article/rs-385…
409/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 145 hospitalized patients, 11.0% were smokers

Note: not specified if current or ever

ncbi.nlm.nih.gov/pmc/articles/P…
410/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 6,493 patients, 20.6% had a history of cigarette use

Of 3,708 of them who were hospitalized, 24.5% had a history of cigarette use

link.springer.com/article/10.100…
411/

Spain (adult smoking rate was 24% in 2019)

Of 91 hospitalized patients, 7 were smokers (7.7%)

Note: not specified if current or ever

link.springer.com/article/10.100…
412/

UK (adult smoking rate was 14.7% in 2018)
Italy (adult smoking rate was 23.7% in 2016)

Of 1,538 hospitalized patients in UK & Italy, 7.9% were current smokers (CS) & 39.2% were ex-smokers (XS)

Of 416 of them who died, CS=6.3% & XS=44.5%

Continued
412a/

Patients:

UK: 90.2% (Wales, Scotland, England)
Italy: 9.8%

thelancet.com/pdfs/journals/…
413/

Louisiana, USA (adult current smoking rate was 20.5% in 2019)

125 patients - smoking data not reported

"...no differences in...smoking history, mean total comorbidities, or prevalence of any comorbidity between the alive and expired cohorts"

ncbi.nlm.nih.gov/pmc/articles/P…
414/

Spain (adult smoking rate was 24% in 2019)

Of 196 hospitalized patients, 11.2% were current smokers & 20.4% were ex-smokers

Of 45 of them who died, 6.7% were current smokers & 28.9% were ex-smokers

journals.plos.org/plosone/articl…
415/

China (adult smoking rate was 26.6% in 2018)

Of 99 hospitalized patients, 13.1% were current smokers

academic.oup.com/jid/article/do…
416/

Europe

"We found a negative association between smoking prevalence and COVID-19 occurrence at the population level in 38 European countries."

academic.oup.com/ntr/article/do… Image
417/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 286* hospitalized patients, 11.2% were smokers

Notes:

not specified if current or ever

*reported percentages of smokers don't work out to whole numbers - 286 is an estimate

medrxiv.org/content/10.110…
418/

Israel (adult smoking rate was 19.1% in 2018)

Of 6,538* tested, 19.4% were current smokers

Of 679 who tested positive, 18.7% were current smokers

Note: reported percentage of smokers in people who tested negative didn't work out to a whole number

medrxiv.org/content/10.110… Image
419/

Spain (adult smoking rate was 24% in 2019)

Of 25 patients hospitalized with suspected Covid-19, two were current smokers (8%) & zero were former smokers

Notes:

only 4 cases were confirmed
all survived

preprints.org/manuscript/202…
420/

USA (adult current smoking rate was 13.7% in 2018)

Of 2,033 critically ill patients, 20.7% were current or former smokers

onlinelibrary.wiley.com/doi/10.1111/bj…
421/

China (adult smoking rate was 26.6% in 2018)

Of 43 patients with rheumatic diseases, 11.6% had a history of smoking

Of 27 of them with Covid-19, 11.1% had a history of smoking

Notes:

all data self-reported
76.7% of patients were female

thelancet.com/journals/lanrh…
422/

Italy (adult smoking rate was 23.7% in 2016)

Of 151 home-quarantined SARS-CoV-2 positive individuals, 7.9% said they were current smokers & 17.2% said they were former smokers

Note: 62.9% were female

journals.sagepub.com/doi/10.1177/01…
423/

Mexico (tobacco use rate age 20+ was 11.4% in 2018)

Of 10,925 health care workers who tested positive, 9.4% were smokers

Of 23,338 HCWs who didn't, 9.8% were smokers

"active smoking...had a decreased likelihood of being positive cases"

medrxiv.org/content/10.110…
424/

Mexico (tobacco use rate age 20+ was 11.4% in 2018)

Of 60,121 confirmed patients, 10.5% were smokers

Of 3,530 of them with non-respiratory symptoms only, 11.2% were smokers

Of 2,452 who were asymptomatic, 6.8% were smokers

medrxiv.org/content/10.110…
425/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 306* hospitalized patients, 23.5% were current or former smokers (CFS)

Of 93* with low viral load, CFS=19.4%
Of 153* with intermediate VL, CFS=25.5%
Of 60* with high VL, CFS=25%

Continued
425a/

Note: It appears smoking status data was missing for 8 patients. Calculated from reported data, the total numbers of patients did not work out to whole numbers.

medrxiv.org/content/10.110…
426/

Iran (adult cigarette smoking rate was 12% & adult smoking rate including hookah was ~20% in 2019)

Of 186 hospitalized patients, 4.8% were current smokers (CS)

Of 48 of them admitted to ICU, CS=8.3%

Note: 20 (14.6%) of 138 non-ICU patients died

preprints.org/manuscript/202…
427/

Spain (adult smoking rate was 24% in 2019)

Of 79,071 individuals age ≥50, 16.1% were smokers

Of 349 of them with confirmed cases of Covid-19, 6.6% were smokers

mscbs.gob.es/en/biblioPubli…

Continued
427a/

From patients above:

Of 1,400 nursing home residents, 7.9% were smokers. Of 148 of them with confirmed cases, 5.4% were smokers

Of 77,671 non-nursing home residents, 16.3% were smokers. Of 201 of them with confirmed cases, 7.5% were smokers
428/

China (adult smoking rate was 26.6% in 2018)

Of 155 hospitalized patients, 13.5% had a history of smoking

Of 30 of them with severe or critical cases, 23.3% had a history of smoking

europepmc.org/article/med/32…

Full text (中文): rs.yiigle.com/CN121430202004…
429/

China (adult smoking rate was 26.6% in 2018)

Of 394 hospitalized patients, 9.1% had a history of smoking

rs.yiigle.com/CN121430202004…
430/

China (adult smoking rate was 26.6% in 2018)

Of 141 patients who were mechanically ventilated, 70% were smokers

Notes:

70% of patients were male
not specified if current or ever

journals.lww.com/ccmjournal/Abs…
431/

New York City, USA (adult smoking rate was 13.4% in 2017)

Of 678 hospitalized patients, 28.6% were former or current smokers

academic.oup.com/cid/article/do…
I missed something from the study in tweet 151:

"Few (<5%) patients had a recorded history of vaping; separate analyses could not be conducted for this group."

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More from @phil_w888

May 23, 2021
1/4

My story:

I smoked for a number of years. I liked it. I didn't want to quit, but for years I thought I should. I tried cold turkey, gum, patches. Didn't work for even a day.
2/4

I first heard about e-cigarettes late in 2009. I looked into them, but saw that ecigs containing nicotine were not legal in Canada. I knew they wouldn't work without nicotine, so I forgot about them.
3/4

In 2014 I saw this CBC piece. Nicotine vaping was a possibility after all. I didn't know anyone who vaped & the nearest vape shop was over 200 km away. I researched. A lot.

cbc.ca/news/canada/ne…
Read 4 tweets
Mar 26, 2021
1/4

This is a Big Tobacco vaping cell study.

To me it's more trustworthy than the Tobacco Control or body parts group or NIH-funded vaping cell studies which are published on a regular basis.

Why? Read this short thread.

journals.sagepub.com/doi/full/10.11…
2/4

They were clear about what device and liquid was used, including the pertinent specs.

They were clear about the puffing regimen, including using realistic length & volume of puffs, and they reported air flow (very important).
3/4

They compared the effects to the effects of cigarette smoke.

They were realistic about the limitations of cell studies and didn't make broad generalizations about all vaping products.
Read 4 tweets
Mar 25, 2021
1/

I watched this so you don't have to.

A thread:

2/

This got off to an extremely weak start. The middle of this century stuff is a complete cop-out, and it completely ignores the fact that much is known already.

It did improve, however.

clivebates.com/vaping-tobacco…
3/

Khara seemed to have a good handle of the state of the evidence most of the time. To me, the notion that e-cigarettes should only be a last resort looks unethical though.

Underrated point: most conclusions about vaping are based on what's known about smoking. Bad idea imo.
Read 6 tweets
Jul 11, 2020
A compilation of preprints, peer-reviewed studies, and datasets documenting SARS-CoV-2/Covid-19 patients' smoking status - only the ones with at least 1000 patients.

h/t @ChaunceyGardner for the idea
1/

USA (adult current smoking rate was 13.7% in 2018)

Of 7162 confirmed cases, 1.3% were current smokers (CS) & 2.3% were former smokers (FS)

Of hospitalized patients, CS=2% & FS=4%

Of patients admitted to ICU, CS=1% & FS=7%

2/

New York City, USA (adult smoking was 13.4% in 2017)

Of 4,103 confirmed cases, 5.2% were current tobacco users (CTU) & 16.2% were former tobacco users (FTU)

Of 1,999 of them who were hospitalized, CTU=5.2% & FTU=20.8%

note: unknown counted as never

medrxiv.org/content/10.110…
Read 143 tweets
Jul 6, 2020
The results of preprints & peer-reviewed studies describing the relationship between smoking and SARS-CoV-2/COVID-19 are reported in this thread

Part 2

To see part 1:

Thread reader: threadreaderapp.com/thread/1251956…

Twitter:
422/

Italy (adult smoking rate was 23.7% in 2016)

Of 151 home-quarantined SARS-CoV-2 positive individuals, 7.9% said they were current smokers & 17.2% said they were former smokers

Note: 62.9% were female

journals.sagepub.com/doi/10.1177/01…
423/

Mexico (tobacco use rate age 20+ was 11.4% in 2018)

Of 10,925 health care workers who tested positive, 9.4% were smokers

Of 23,338 HCWs who didn't, 9.8% were smokers

"active smoking...had a decreased likelihood of being positive cases"

medrxiv.org/content/10.110…
Read 5167 tweets

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