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@hvanspall @aayshacader @Pooh_Velagapudi @zchagla @S_brimble @HeartOTXHeartMD @mmamas1973 @fischman_david @BoggildLab @DocSavageTJU @SilCastelletti @GiuseppeGalati_ @AndreasGevaert @IAmDrIbrahim thelancet.com/journals/lance…

❇️placebo controlled
❇️Sx onset ▶️enrollment 12 days, O2 sat 94% on RA, xray confirmed pneumonia
❇️Concomitant use of lopinavir–ritonavir, interferons, & steroids
❇️PEP clinical improvement to 28days
❇️6-point ordinal scale from 1=discharged ➡️ 6=death
2/
@hvanspall @aayshacader @Pooh_Velagapudi @zchagla @S_brimble @HeartOTXHeartMD @mmamas1973 @fischman_david @BoggildLab @DocSavageTJU @SilCastelletti @GiuseppeGalati_ @AndreasGevaert @IAmDrIbrahim Remdesivir NO statistically significant clinical benefits.
However, the numerical ⬇️ in time to clinical improvement w early initiation of Rx.
May be valuable w bed utilization if not mortality benefit
3/
@mmamas1973 @AnkurKalraMD @HeartOTXHeartMD @DrFerNunez @ShelleyZieroth
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