Encouraging news today on Moderna vaccine. Technology will eventually let us greatly reduce the covid threat and reclaim normal times. Early data shows it generates robust immune reaction, and its dose dependent. Getting dose right is key. Moderna now testing a new 50mcg dose 1/x
We must establish regulatory measures for antibody titers, clinical measures of benefit, to serve as clear benchmarks of success for studies. Right now FDA requires neutralizing antibody titer of at least 1:160 for convalescent serum donors. Is that the level for a vaccine? 2/x
There's some suggestion vaccines could protect us from bad symptoms of covid but not totally protect us from getting the infection (like a flu shot) biocentury.com/article/305211. The good news is there's now accumulating evidence across multiple products that we should get a vaccine.
