It's taken a while for me to process the #AVCT news today, but I am now very excited by it.
AVCT has formed a global, exclusive sales and marketing agreement with Medusa19. It covers direct-to-consumer sales only (DTC).
Medusa is a new company, founded by Boohoo's founders. 1/9
Initially, Medusa will sell #AVCT's #COVID19 rapid antigen test, but will also sell other home tests developed by AVCT in the future.
The medical diagnostics DTC market is nascent. It is simple to perceive that the current pandemic and resultant lockdowns could catalyse... 2/9
...explosive growth for it (as is the case with most other industries that have always previously been brick-and-mortar retail-centric).
Medusa's founders - esp. the exec Chairman of #BOO, Kamani - has essentially mastered the DTC market for affordable fashion. Evidently... 3/9
...he envisages a colossal growth opp. for new entrants (with significant relevant experience) in this nascent med. diag. DTC market.
Medusa will be focussing ALL of its resources on marketing and selling #AVCT's test. Whilst those resources might seem non-existent now, 4/9
...one would expect that Kamani knows precisely what is required to build out a global reach for Medusa in lightening quick time (and the shareholders have the financial resources to achieve this).
So whilst Amazon might have a far greater reach, Medusa will provide far... 5/9
For AVCT, the profit-sharing arrangement essentially means that it has created an associate company to carry out its marketing and sales, removing operational risk and freeing up mgmt. time to focus on what it's best at.
I would suggest...6/9
..that the profit-sharing arrangement is highly attractive for #AVCT, elsewise they would have joined forces with a major distributor ( , , , , etc).
It's becoming increasingly clear that the LFT will be AVCT-branded: There should be news on additional... 7/9
OEMs (besides Cytiva) in the next couple of weeks.
I also expect other commercial / distribution partners shortly to take charge of other routes to market.
There is also the possibility of a partner white labelling #AVCT's Affimer reagents to be used in its own-branded LFT. 8/9
In summary, I think the Medusa deal - whilst certainly riskier than other routes #AVCT could have taken - could ultimately be a masterstroke.
Mgmt is driving AVCT forward not just at breakneck speed, but with fabulous astuteness.
Expecting an action-packed few weeks! 9/9
• • •
Missing some Tweet in this thread? You can try to
force a refresh
There are many stale holders who have been underwater for 18+ months, who will be happy to take some cash out now, in this ongoing cost of living crisis. That is understandable.
There will also be traders exiting, having positioned for this update.
Furthermore, the...
2/20
...wider investment community has not yet heard of, and even more so not appreciated the significance of, today's news at #AVCT.
Finally, I will state with a high degree of confidence that today's RNS opens the floodgates for numerous more updates in the near future.
Volume returning really nicely to the small cap space, which is creating excellent trading conditions.
My average holding period in the Short-term Trading Portfolio is still around 16 sessions / 3 weeks.
Seemingly contrary to many, I consider trade entries based both on..
2/18
...fundamentals (see two recent successful trades in MMAG and SPEC, with rationales for trades founded on earnings metrics), and on stories and associated sentiment (BSFA being most recent example).
I don't subscribe to only utilizing one or the other; the same way as I...
@AnEarlofWisdom Hi Earl, I can't see any of the posts, as I'm blocked by those accounts (or I've blocked!), but I've been told there's a lot of scaremongering about various things:
1) Delay in trial; 2) Dox not activating much in TME; 3) Low cash balance, and thus possible placing coming.
1/8
@AnEarlofWisdom On the contrary, except for Cohorts 1 and 2 taking longer than expected (due to patient withdrawals - nothing whatsoever to do with #AVA6000 itself), #AVCT's progress in 2022 could not be stronger.
The DE to 200mg/m2 was the ultimate target, so that nullifies point 2) ⬆️.
2/8
@AnEarlofWisdom Licensing deals for targeted oncology drugs - even those at pre-clinical stage, like 3996 - have been monstrous in recent times (e.g. $100m cash upfront for an antibody-drug conjugate, just last month ⬇️).
...substrate to FAP is so high that the concentration ratio of active doxorubicin in the tumour : healthy tissue, will negate the requirement for increase in dose size. [My view!]
Enough dox is already becoming active in the tumour micro-environment, at the current...
3/8
$SGEN specializes in antibody-drug conjugates ('ADC') - a relatively novel form of targeted cancer treatment.
@avacta's targeted cancer treatment platform, preCISION, has the real potential of generating pro-chemotherapies that are MORE targeted than ADCs, and thus...
2/6
...also potentially capable of delivering a more potent drug payload.
#AVCT will be announcing the results of the first preCISION prodrug P1 trial (AVA6000) in the next few months.
Success will mean the platform could be used to modify many other existing chemotherapies.
3/6