Was asked for personal favorite resources for improving methods and statistics skills. I promised to make it a thread, so here it is

1/n
I work in medical research, so that is going to be my focus here too. But I’d like to think the resources are relevant to a wider audience

This list should not be taken as a guide to become a statistician, nor is it a must-read list for all academics (obviously)

2/n
My personal view is that medical research would benefit from involving trained statisticians earlier and more frequently; not from everyone trying to become one

Here are some good arguments by @statsepi:
medium.com/@darren_dahly/…

And some more: medium.com/@darren_dahly/…

3/n
That said, it is certainly not bad to learn more about methods and stats than the basic (med) curriculum provides, especially if you are (or want to become) a (medical) researcher

As @jacalvache pointed out: collaborating with a statistician may always be an option

4/n
The obvious starting point is: here.

Yes, @Twitter has taught me a ton about methods and statistics. Follow the hashtags #epitwitter (@epi_twit) and #statstwitter (@statstwitbot). Even #econtwitter is good when they are not talking about linear probability models

5/n
Another worthwhile resource is @f2harrell’s Data Methods forum. Many interesting discussions going on there, but I seem to find myself back at this particular discussion about statistical myths started by @ADAlthousePhD:

discourse.datamethods.org/t/reference-co…

6/n
Also note this free online #bbrcourse run by @f2harrell (did not attend, but heard good things about it").

hbiostat.org/bbr/schedule.h…

7/n
The @bmj_latest statistics notes series is also an excellent resource for short and accessible articles: bmj.com/specialties/st…

Another gold mine: the “Research methods & reporting” articles
bmj.com/research/resea…

8/n
Talking about reporting: @EQUATORNetwork lists more than 400 relevant reporting guidelines (plz use them!). Many guidelines also come with so-called “Explanation and Elaboration” papers, which are insightful and full with interesting references

equator-network.org

9/n
There are also some excellent courses to follow. Too many to mention here, so just a few links here:
netherlands.cochrane.org/cursussen-en-w…
erasmussummerprogramme.nl/summer-program…
keele.ac.uk/pcsc/newsandev…

10/n
(Shameless plug) you can also enroll in our MSc epidemiology program @UniUtrecht (face to face and/or distance learning):
uu.nl/masters/en/epi…

11/n
Finally, there are some books I should mention

12/n
Statistical rethinking by @rlmcelreath is a good place to start, even if you are not planning on becoming a Bayesian

xcelab.net/rm/statistical…

13/n
If you want to know more about prediction modeling this selection is highly recommended (increasing technicality ->)

global.oup.com/academic/produ…
springer.com/gp/book/978303…
springer.com/gp/book/978144…
web.stanford.edu/~hastie/ElemSt… (free)

14/n
This book (available for free) also deserves recommendation if you are interested in the principles of advanced statistical modeling

link.springer.com/book/10.1007/9…

15/n
For learning more about randomized controlled trials, this is the place to be IMHO:

amazon.com/Statistical-Is…

16/n
This book provides a great introduction to epidemiology. With a discount code available in the linked tweet below



17/n
This is another key epidemiology book that should be mentioned.
amazon.com/Modern-Epidemi…

18/n
I'll probably think of more later, but this is it for now.

19/n

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More from @MaartenvSmeden

14 Oct
HOW DO YOU DEVELOP A NEW PREDICTION MODEL?

This [THREAD] has been long in the making and is arguably overdue

1/138
I'll assume you have some basic knowledge of prediction models and will be relatively short on the technicalities

lets suppose you interested in developing a prediction model for disease X

2/138
There are probably a few dozen prediction models already developed for disease X!

most of them have never and will never be used

so... are you really, really, really sure the world is waiting for a new prediction model for disease X?

/138
Read 4 tweets
16 Sep
the ultimate reviewer #2 bingo card
key citations 👇
unclear analysis aims
stat.berkeley.edu/~aldous/157/Pa…

evidence of absence fallacy
bmj.com/content/311/70…

data dredging
bmj.com/content/311/70…

noisy data fallacy
science.sciencemag.org/content/355/63…
Read 6 tweets
3 Aug
The BMJ just published an editorial about living systematic reviews worth a read, which is new territory for just about everyone bmj.com/content/370/bm…

ICYI, I have a few thoughts to share
We were fortunate to have produced @bmj_latest first living review
bmj.com/content/369/bm…
The aim of our review is (and always was) to give an overview and appraisal of currently available diagnosis and prognosis models related to COVID-19

But this is a fast moving field: from 31 models reviewed in April to 145 models reviewed in our 2nd update published in July
Read 14 tweets
11 Jul
Used to get annoyed by stats consult clients who insisted they needed machine learning for their very large dataset (N of 100s or few 1000s). Now I tell them logistic regression *is* machine learning and everything is great again
And since machine learning is a sub field of AI, logistic regression is also AI. I should have understood this sooner
Logistic regression as statistical model
- prepare data
- estimate model
- evaluate performance
- report

Logistic regression as machine learning
- prepare data
- estimate model
- evaluate performance
- report
Read 4 tweets
19 May
The definitive guide to COVID-19 prognosis modeling success

1) Do not explain where the data come from (country) or when (study dates) they were obtained. Do not specify inclusion or exclusion criteria
2) Do not define a target group. Talk generically about COVID-19 patients, do not define how they were recruited
3) Do not provide a table with patient characteristics. In particular, do not mention use of medication or co-morbidities
Read 18 tweets
13 Apr
Let's talk about the "risk factors" for COVID-19 for a moment

1/n
We talk about risk factors all the time. Not just in the medical scientific literature: you will find risk factors being discussed in the popular media and on social media too

Exhibit A: nytimes.com/reuters/2020/0…

2/n
The term "risk factor" is popular in medical research. It has been used in literature since at least the 1950s

BUT definitions for what a risk factor really is or should be varies. As this article argues quite convincingly bmj.com/content/355/bm…

3/n
Read 15 tweets

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