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API molecules are made by connecting fragments/intermediates. This joining process-synthesis takes place in the presence of ´solvent´. When India is taking a giant leap in manufacturing APIs, it needs thousands of liters of solvent
Listing some commonly used solvents here
Ethanol, Methanol
Toluene, Xylene
Acetone
THF, DMF, DMSO
Dioxane
Acetonitrile
DCM
Ethyl acetate
Diethyl Ether
Cyclohexane
Acetic acid

Find out companies who make them or which solvents are being imported

India needs ´Atmanirbhar´ supply chain for becoming competitive
Surprised to know that India is import dependant on Acetic acid. About 75% is made from methanol. The biological route accounts for only about 10% of world production, for the production of vinegar as many food purity laws require vinegar used in foods to be of biological origin
Recently #Deepaknitrite started making Acetone. As solvents are low margin products, the producer needs to make it on a huge scale like what Deepak did
Few makers i found are

Acetone; #DeepakNitrite
Methanol; #DeepakFertilizer
Ethyl acetate & Acetonitrile; #IOLCP
DCM; #GujaratAlkalies

Please feel free to add
One solvent can be converted to another in a few cases, Possible forward integrations and companies can be

Acetone to IPA; #DeepakNitrite
Methanol to Acetic acid; #DeepakFertilizer

Ethyl acetate which had $3.3 billion Global sells 2019, is made from acetic acid and ethanol
#Alkylamine is making Acetonitrile & Can make DMF

It's a complex technology product as per management
with only 3 players globally, they developed in-house technology.

Found some interesting knowhow and supply chain below
As you might have realized, its complex and fragmented area.

But if India is becoming API hub, it needs a robust, reliable, and cheap local supply chain of solvent.

Those companies tapping this area and making import substitutes will be beneficiaries.
Applications of Acetic acid/anhydride nicely summarized by @punitbansal14

#JubilantLife is a dominant player

Thanks for pointing out @unseenvalue

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Keep Current with Prasad Wakchaure 🇸🇪 🇮🇳

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