Thread by @foldingathome

🚨🚨NEW BLOG POST🚨🚨
Starting this week, F@h will have weekly “sprints” (GPU projects 134xx) to prioritize compounds to test for the @covid_moonshot! A progress bar on our homepage tracks the progress made each week. Check out our new blog post for more: foldingathome.org/2020/07/28/int…

@covid_moonshot F@h has worked closely with the @covid_moonshot to identify and develop inhibitors against the SARS-CoV-2 main protease (previously featured on #FAHMeetTheProteins). foldingathome.org/2020/05/28/the…

@covid_moonshot So far, over 800 compounds have been designed, synthesized, and tested, and molecules have already been found that inhibit the protease! These are the launchpads for molecular optimization. All the compounds and data can be viewed at: postera.ai/covid/submissi…

@covid_moonshot With the collaborative power of @covid_moonshot, compounds that inhibit the protease are studied experimentally with powerful X-rays by @DiamondLightSou to determine how they fit into the binding pocket! You can view these structures here: fragalysis.diamond.ac.uk/viewer/react/p…

@covid_moonshot @DiamondLightSou With the exascale power of F@h, we are now running weekly “sprints” to help chemists prioritize which compounds to make and modify! The data from these sprints will help chemists design and optimize their strategies. foldingathome.org/diseases/infec…

@covid_moonshot @DiamondLightSou The first sprint just started! You can check out progress on our weekly sprints using the progress bar on our homepage: foldingathome.org

As always, all F@h data and molecules tested will be posted online, free of patents, for others to view and download! You can keep up with molecules that are being tested at postera.ai/covid

Learn more from our new blog post:: foldingathome.org/2020/07/28/int…