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Folding@home Profile picture
Folding@home
@foldingathome
We are a group of academic labs around the world that perform biomedical research using the computing power of volunteers | Join us at: https://t.co/5sH7Ox3Xih
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Dec 17, 2020 • 9 tweets • 5 min read
🚨#COVID19 PAPER ALERT🚨
F@h simulations of the #coronavirus Nsp16 protein (1) reveal the structural mechanism of its activation, which ultimately enables the virus to escape our immune system, & (2) detect a ‘cryptic’ pocket to block Nsp16’s action.
biorxiv.org/content/10.110… For successful infection, #coronaviruses use a protein called Nsp16 that modifies the viral genome so that the virus avoids an immune response. Nsp16 works by binding 2 substrates: RNA (green) and SAM (pink). Viruses and humans contain similar (homologous) proteins.
Jul 29, 2020 • 8 tweets • 6 min read
🚨🚨NEW BLOG POST🚨🚨
Starting this week, F@h will have weekly “sprints” (GPU projects 134xx) to prioritize compounds to test for the @covid_moonshot! A progress bar on our homepage tracks the progress made each week. Check out our new blog post for more: foldingathome.org/2020/07/28/int… @covid_moonshot F@h has worked closely with the @covid_moonshot to identify and develop inhibitors against the SARS-CoV-2 main protease (previously featured on #FAHMeetTheProteins). foldingathome.org/2020/05/28/the…
Jun 30, 2020 • 14 tweets • 19 min read
🚨#COVID19 PAPER ALERT🚨
With your help, F@h became the first #exascale computer, collected 100,000X more data than a normal paper, learned how the #Demogorgon evades our immune system, and discovered drug targets called ‘cryptic’ pockets (#FAHPockets)!
biorxiv.org/content/10.110… With over a million people downloading F@h, we reached #exascale computing speed within weeks. This made us >5X faster than the IBM Summit supercomputer, the fastest traditional supercomputer in the world!
Mar 27, 2020 • 11 tweets • 2 min read
Let’s talk about how simulating proteins with Folding@home fits into drug discovery and development.

[Thread] 1/11 First: what’s the difference between a vaccine and a drug? 2/11
Mar 24, 2020 • 10 tweets • 3 min read
Thank you to everyone who asked us questions during last week’s AMA! reddit.com/r/pcmasterrace…

Here are some quick highlights: First, we want to say a huge thank you to foldingforum.org for providing a ton of support. If you’re new to our community and have a technical question, this is a great spot to look!
Mar 16, 2020 • 8 tweets • 3 min read
Thank you to everyone who has been donating their resources! Here are some answers to your frequently asked questions.

How can I donate my time for #COVID19? Download and install the client from foldingathome.org; Under topic, select ‘ANY’ (1/8)

How is Folding@home being used for #COVID19?(2/8)