Kai Kupferschmidt Profile picture
Sep 25, 2020 16 tweets 16 min read Read on X
"So-called lockdowns and the impact on global travel and trade have already taken such a heavy toll”, says @DrTedros at @WHO #covid19 presser. "The global economy is expected to contract by trillions of dollars this year."
@DrTedros @WHO "Many countries have poured money into domestic stimulus packages”, says @DrTedros. "But these investments will not on their own address the root cause of the economic crisis – which is the disease that paralyses health systems, disrupts economies and drives fear and uncertainty“
@DrTedros @WHO Today, @WHO and partners are publishing strategy plan and investment case for scale-up phase of the ACT Accelerator, says @DrTedros.
Aims to deliver
- 2 billion doses of vaccine
- 245 million treatment courses
- 500 million tests
to low/middle income countries by end of 2021
@DrTedros @WHO Current financing gap is $35 billion, says @DrTedros. "To put it in perspective, $35 billion is less than 1% of what G20 governments have already committed to domestic economic stimulus packages… It's roughly equivalent to what the world spends on cigarettes every two weeks"
@DrTedros @WHO Q: World is close to 1 million #covid19 deaths. Is it possible another million will die?
“One million is a terrible number and I think we need to reflect on that before we start considering the second million”, says @DrMikeRyan. "There is a lot that can be done to save lives."
@DrTedros @WHO @DrMikeRyan “Whether another million people die of #COVID19 is not a function of whether or not we have a vaccine”, says Bruce Aylward. "It's a function of whether or not we put the tools and approaches and knowledge that we have today to work to save lives and prevent transmission."
@DrTedros @WHO @DrMikeRyan Q: how to get especially young people to change behaviour?
Older people get this wrong, says @DrMikeRyan. "The vast majority of young people that I know are just as committed to containing this disease and saving lives as anybody else. In fact, more committed."
@DrTedros @WHO @DrMikeRyan “We have to see how we can support youth, like we support any sector in our society, to protect themselves and protect others”, says @DrMikeRyan. "I really hope we don't get into a sort of finger wagging... not a dialogue that is going to work, it certainly never worked with me."
@DrTedros @WHO @DrMikeRyan (Side note: For 9 months now I have been impressed by @DrMikeRyan’s #Covid19 communication. This is not about some kind of technical skill, his words are powerful because they are always informed by his humanity, by a will to understand not judge, to listen not talk.)
@DrTedros @WHO @DrMikeRyan Q about Africa and its success so far.
“We're not out of the woods anywhere and I would say we're not out of the woods in Africa”, says @DrMikeRyan. Lab capacity increased immensely, but "still many areas outside main cities where testing is not as good as it should be."
@DrTedros @WHO @DrMikeRyan "Africa has many lessons to teach the world about how to be resilient, how to be creative”, says @DrMikeRyan. "I have learned, side by side with many of my African colleagues on the front line and I guarantee you, I've learned more than I've ever taught."
@DrTedros @WHO @DrMikeRyan “Thing I've noticed over my career with colleagues who've been trained and worked in Africa, is that they immediately think about the community dimension as the first thing they think about not the last thing they think about”, says @DrMikeRyan.
@DrTedros @WHO @DrMikeRyan Q about resurgence in Europe.
“We are seeing in a number of countries right now, an increasing trend in cases. And part of that is due to the fact that we have better surveillance”, says @mvankerkhove. “But what is worrying to us is an increase in hospitalizations"
@DrTedros @WHO @DrMikeRyan @mvankerkhove Cases increasing fast in parts of Europe, says @DrMikeRyan. “We are seeing hospitals starting to have more occupancy, we're seeing ICUs beginning to have more occupancy, we're starting to see a small uptick in deaths in older people and that will inevitably become more.
@DrTedros @WHO @DrMikeRyan @mvankerkhove Lockdowns are last resort, says @DrMikeRyan. “To think that we're back in last resort territory in September, at the beginning of the autumn. I think that’s a pretty sobering thought. Have we really exhausted all of the tools, so we're back to lockdowns as a solution? "
@DrTedros @WHO @DrMikeRyan @mvankerkhove “We have to move fast”, says @DrMikeRyan. "I think Europe has as a lot of work to do right now to stabilize the situation and bring the transmission under some kind of control"

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More from @kakape

Jun 20
One question at the heart of the #h5n1 outbreak in US cows has been: Is there something special about this virus? Or is H5N1 generally able to do this and this particular version was just "in the right place at the right time"?
Quick thread, because it seems we have an answer
Researchers in Germany have done an experiment in a high-security lab infecting cows directly with the strain of #H5N1 circulating in cows in the US (B3.13) and infecting others with an #h5n1 strain from a wild bird in Germany.
(I wrote about the plans here: )science.org/content/articl…
In both cases they infected the udders directly through the teats and in both cases the animals got sick. They "showed clear signs of disease such as a sharp drop in milk production, changes in milk consistency and fever." That suggests there is nothing special about B3.13.
Read 8 tweets
Jun 13
The thing that I find most frustrating about the entire mpox/gain-of-function debate is how the uncertainties that lie at the base of it all just become cemented as certainties that are then carried forward.
(If you know anything about me you know I love me some uncertainty...)
Most importantly: The interim report on the investigation into these experiments released on Tuesday numerous times calls clade II "more transmissible" or even "much more transmissible".
But that is a claim that has very little evidence at all.
In fact you can find plenty of literature that argue the exact opposite, that in fact clade I is more transmissible.
Just, as an example, here is Texas HHS:
"Clade I MPXV, which may be more transmissible and cause more severe infection than Clade II..."
dshs.texas.gov/news-alerts/he…
Read 7 tweets
May 30
Some more details on the latest (3rd) human case of #H5N1 #avianflu linked to the current outbreak in dairy cows:
- second case in Michigan but not linked to the other case (different farm)
- reported cough and eye discomfort with watery discharge
- given oseltamivir, isolating at home
"As with the previous two cases (one in Texas, one in Michigan), the person is a dairy farm worker with exposure to infected cows, making this another instance of probable cow-to-person spread."
"The patient reported upper respiratory tract symptoms including cough without fever, and eye discomfort with watery discharge.  The patient was given antiviral treatment with oseltamivir, is isolating at home, and their symptoms are resolving."
Read 5 tweets
May 16
A thought on communication:
In today’s presser's opening statement @USDA presented work on killing H5N1 in ground beef through cooking. They mentioned no virus being present at 160°F and 145°F. Only later when someone asked, they mentioned that at 120°F there was some virus left.
@USDA I have thought a lot about trust and transparency in the wake of the #covid19 pandemic and to me this seems exactly the kind of communication style that does not build trust.
Yet another lesson not learnt in my book...
@USDA For reference, my thread on this:
Read 4 tweets
May 16
Researchers at @USDA have done a “ground beef cooking study” to test at what temperature #H5N1 in meat is killed. To be clear: Tests have found no H5N1 in beef samples, so this was done “in the interest of scientific inquiry and to further reaffirm consumer confidence”
@USDA So researchers added #H5N1 to ground beef patties then cooked them:
“There was no virus present in the burgers cooked to 145° [Fahrhenheit] internal temperature, or roughly medium, or 160°, which equates with a well done burger, which is the recommended cooking temperature”
@USDA At lower temperatures, some virus survived. "Cooking to I believe it was 120° [Fahrenheit] did show that there was virus still in the cooked hamburger patty, although at much, much reduced levels."
(But remember that these were experimentally infected burgers.)
Read 4 tweets
May 16
#h5n1 presser by @USDA and @HHSGov just ended. Had some some interesting bits (but what I would really love to see is still... serology):
@USDA @HHSGov - USDA researchers have done a “ground beef cooking study” to test at what temperature #H5N1 in meat is killed. To be clear: Tests have found no H5N1 in beef samples, so this was done “in the interest of scientific inquiry and to further reaffirm consumer confidence”
@USDA @HHSGov So the researchers added H5N1 to ground beef patties then cooked them. “There was no virus present in the burgers cooked to 145 degrees internal temperature, or roughly medium, or 160 degrees, which equates with a well done burger, which is the recommended cooking temperature”
Read 9 tweets

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