This series on COVID tries to analyse data objectively and aims to avoid the twin dangers of fear & complacency; prevent a large second wave & a second lockdown.

No 7. Is the NHS in the same position now as it was on March 23rd? And does that mean we need another lockdown?
Over the last few days, much has been said and written about the fact that there are now more patients in hospital with COVID than there were on ‘lockdown day,’ March 23rd, and some are claiming this justifies a second national lockdown to prevent the NHS being overwhelmed. .
While it is true that that there are more patients in hospital with COVID now (3332) than there were on March 23 (3160), the trajectory is very different (as I explained it would be 4 weeks ago - due to social distancing, isolation, masks, etc.)
In March, the no. of COVID patients in hospital was doubling every 3-4 days whereas now it is 14 days.
The no. of cases in the week before lockdown (which predicts future admissions) was about 1.5 million (& doubling every 3 days) whereas last week
we had about 200,000 cases and a doubling time of 10-12 days. Also, looking at daily admissions, they are currently half of what they were on March 23rd (527 vs 1119) – then, they were doubling every 5 days, now it’s every 14 days.
Therefore, while the first lockdown was justified on the basis that admissions were rising so fast that the NHS would have been overwhelmed without one (leading to even higher numbers of both direct and indirect than we suffered), the same does not apply this time.
The NHS overall should be able to cope with the current level of admissions/inpatients, particularly with the additional capacity we now have with the Nightingales and private sector. This judgement is also based on my own experience:
the reason I volunteered to go back to the frontline in March was because admissions were rising so quickly & we had seen what had happened in Italy and feared the same would happen here. Thankfully, although April was like nothing I had seen before, even in the worst flu seasons
it wasn’t as bad as we feared – partly because many of our usual patients stopped coming to hospital – with tragic consequences. (If you are interested in reading my experience of the first wave, the link is below– many of the issues I raised then are equally relevant now.)
This week, locally we have had far fewer COVID admissions than we did at the end of March. However, I do recognise that admissions are much higher in some areas than others (which is why measures should be locally targeted)
and it is also true that the NHS can’t cope with the same level that we reached at the peak in April while keeping all other services running (which we must do this time - particularly with the huge backlog we now have) - there are simply not enough staff or beds.
Therefore, we must keep levels lower this time – both so that we can continue treating all of our patients and so that our patients are not scared of coming to hospital.
This will save the most lives from all causes, not just COVID - which should be our aim.
In conclusion, although this is not a repeat of the first wave & we are not where we were on 'lockdown day', this is because most of us are following the current measures to control the virus and the situation can change quickly if we don't.
And I hope those who are not doing so will realise that by making these smaller sacrifices now, we can avoid the much greater harms of a second lockdown.

References below:
coronavirus.data.gov.uk/healthcare
mrc-bsu.cam.ac.uk/now-casting/
conservativehome.com/platform/2020/…

conservativehome.com/platform/2020/…

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More from @drraghibali

13 Oct
Thanks to @IainDale for inviting me on to @LBC to explain why a national 'circuit-breaker' lockdown is not justified. There is not enough evidence that the benefits of this policy would outweigh its harms - which must be the benchmark - especially in areas where cases are low.
However we must also continue to keep hospital admissions low enough to enable all NHS services to keep running; and also low so that people are not scared of going to hospital, school, shops, restaurants, etc. as happened first time around - but this should be achieved through
measures that minimise overall harm i.e. social distancing, self-isolation, reducing social contacts indoors, masks, etc. - which remains the best way to prevent a second national lockdown.
Read 4 tweets
13 Oct
I welcome the release of the SAGE documents summarising the evidence for the effectiveness & harms of different interventions which I have long called for - it's essential this is shared with other scientists & the public. (Link below) Today's thread will briefly summarise
why the evidence for all these interventions is weak which is why there is uncertainty and disagreement between scientists about which policies are most effective / least harmful but of course we have to make decisions now based on the evidence we have.
For any disease, ideally we try to establish whether an intervention is effective (e.g. in saving lives, or improving the quality of life) in randomised controlled trials where all other factors are controlled for and then randomly assign patients to the intervention or a control
Read 12 tweets
6 Oct
This series on COVID tries to analyse data objectively and aims to avoid the twin dangers of fear and complacency; prevent a large second wave - and a second national lockdown.

No 7. Flu has not killed more people than COVID over the last few months - but staying at home has.
There has been a widespread misunderstanding of the graph below which the ONS releases every Tuesday with many reports and people saying that influenza has been killing many times more people than COVID-19 over the last three months.
This is mainly because of the way deaths are recorded by the ONS (who combine the categories for influenza & pneumonia) and also the difference between ‘dying of’ a disease (an actual underlying cause of death) and ‘dying with’ a disease (did not contribute to the death).
Read 15 tweets
28 Sep
This week, I will be posting a series of threads on the risks of a second wave - and of our response to it. I hope this will help us overcome the twin dangers of fear and complacency, prevent a second wave - and a second lockdown. This is no. 3: How deadly/dangerous is COVID-19?
There has been a lot of disagreement about how deadly Covid-19 is – with many people hugely overestimating the risk and others insisting it is no worse than flu. We now have much better evidence with actual data (as opposed to modeling) to answer this question.
Firstly, you need to look at the infection fatality rate (IFR) which is the percentage of those INFECTED who die (not just those who are diagnosed as positive cases - which is a huge underestimate of the actual number infected -eg in the UK, we have recorded roughly 400,000 cases
Read 10 tweets
26 Sep
On the risks of a second wave - what can we learn from other countries experience?

The evidence is mixed and between-country comparison have lots of limitations so you can come to different conclusions based on which countries you look at. However, generally it is true that
those countries experiencing larger second waves after lifting lockdowns are those that had smaller first waves so more of their population remain susceptible to infection. But it is not true that the second waves are only causing cases and not deaths eg Israel, Romania, Morocco
The converse is also true (so far) in that countries with large first waves are having smaller second waves, and particularly in cities like New York where 20 per cent of the population has developed antibodies, there is no second wave yet. This was surprising as it was expected
Read 9 tweets
25 Sep
I'm still seeing two widespread misunderstandings of this graph and the data.
The first is that cases are now as high as they were during the first wave – leading to unnecessary fear – and the second is that hospitalisations and deaths (and test positivity) are much lower now than when we had a similar number of cases – leading to unjustified complacency.
These case count (and test positivity) comparisons are completely misleading, because far more tests are being carried out now than in the first wave when they were only being done on those in hospital, not in the community.
Read 9 tweets

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