Schools + comments on some sources (THREAD)

This recent schools article makes some great points, and @apoorva_nyc is one of the top science journos on covid out there, but a few of the sources cited in this one have some issues, especially a few pages from govt websites. 1/22
-UK link is outdated. For late Oct, random sampling estimates all 3 child age-groups more infected than any adult group. 2-11s are 2nd highest!

-The Netherlands govt website badly mischaracterises its study.

-Pediatrics childcare-worker study and NYC article need comment. 2/22
UK schools opened at start of September. No remote school, even for families with medical vulnerability. No temporary home schooling either.

The article’s linked UK govt webpage shows Sept infection ⬆️ for secondary-school and ⬇️ for primary-school and a few other groups. 3/22
EXCEPT these graphs are outdated and later required serious revision.

As @ChrisGiles_ demonstrates, ONS modelling has a track record of underestimating growth for the end of the time period shown, and then later revising. See especially the green late-September dip. 4/22
.@IndependentSage graphed the latest ONS random-sampling results. Spreadsheet says by 16 Oct, the 4 highest-infection age groups were

16-24-yr-olds (2.05%), 2-11-yrs (.79%), 11-16-yrs (.66%), and 50-69-yrs (.63%).

Ie, 2-11’s 25% higher than the highest all-adult bucket! 5/22
Yes, ONS previously underestimated infection for final weeks, but prior underestimates were fairly uniform across age groups.

This large-N random sampling also reveals that UK symptom-based PCR testing has substantially under-reported child infection, relative to adults. 6/22
Why 2-11 > 11-16? Primary students get many colds. Avoiding testing cold-like symptoms and asymptomatic kids means many cases missed.

More 11-16 cases found with PCR. Many secondary schools home-isolated whole yr groups. Also, MASKS: many UK primary schools *forbid* masks. 7/22
Kids dominating infection isn’t just a UK thing. It appears to be a “wide-spread testing in context of circulating kids” thing. Like Isreal’s Health ministry’s recent findings.

TOI says was based on >2 million tests, for a population of <9 million.
timesofisrael.com/health-ministr… 8/22
Next source: Netherlands govt webpage.

This page totally mischaracterises a small sample-size 54-household study of families of covid-infected patients.

In the actual study, 12-17-yr-old household contacts had a *higher* infection rate (34%) than 18-45-yr-olds (28%). 9/22
Total 18+ rate: (10+13/36+31)=34%, same as 12-17.

The only groups with new +ive PCR tests at 2-3 weeks were 1-5- and 6-11-yr-olds, with 1 new case each, totaling to 16% and 18%.

So overall, the 3 child hh contact grps had 57%, 64%, and 121% the infection rate of 18-45s. 10/22
Next source: Pediatrics study on US childcare workers for mostly <6s.

This was a much better source: large sample size, good collection of contextual data...

But they failed to ask workers the most important question: what did you do for income if your center closed? 11/22
Because unlike school teaching, infant childcare cannot be done remotely, and *many* childcare workers don’t have enough savings to go months with no income.

So what did they do instead for money—individual childcare in less regimented settings, food delivery?, what? 12/22
With P<.01, home-based childcare workers had a 59% higher infection risk than non-home-based. This notably was independent of whether officially required to be closed.

Home-based workers would likely have an easier time arranging unofficial childcare work for themselves. 13/22
There were also paradoxical effects.

More masks/hand-washing/social-distancing in public meant a *higher* infection rate (OR 1.16, P=.24).

Granted P=.24, but for P=.001, avoiding friends + extended family, and (especially) avoiding eating out, meant 27% more infection. 14/22
To explain this, authors guessed maybe higher vigilance occurred in higher-covid areas.

OTOH, maybe workers used more masks etc if forced to *work* in exposed settings. Less eating out could also have correlated with more financial vulnerability and greater need to work. 15/22
Valid comparisons require knowing what the control group did.

All this study shows is that whatever childcare workers did *after* they lost their official childcare job, that provided comparable infection exposure to what open childcare centers provided for other workers. 16/22
Next up: the NYC schools article.

Whereas the article reports 378 school cases found by targeted testing, random sampling of 16.3K staff and students found 28 cases.

BUT: what matters is how that compares to *community* levels. nytimes.com/2020/10/19/nyr… 17/22
Random sampling for the school week from 9 Oct (9+13-16, schools closed on 12th) found 28 cases out of 16.3K tests, or .17%.

Avg +ive targeted PCR tests for NYC then was 461/8.4 mil/day, or .038% +’s/pers/week.

To compare, we must rescale the latter % for missed cases. 18/22
In the UK that week, that rescale factor was .79%/.17% = 4.6. For NYC, that gives .038% x 4.6=.17%.

But UK has higher infection and only tests symptomatic. NYC tests anyone who wants, for free. So NYC likely <.17%. Just hard to guess how much less. NYC schools were .17%. 19/22
Back to @apoorva_nyc’s article.

It made some great points, like how in Sweden, upper secondary schools closed in spring, and those remote teachers had median levels of infection. But teachers for lower secondaries (all in-person) were among the most-infected professions. 20/22
On the flip side, Boston recently stopped in-person schooling even for severely-disabled and highly socially vulnerable children.

That’s utterly ridiculous.

Surely they can find enough high-quality PPE and ventilated space to teach this tiny group.
boston.com/news/education… 21/22
This isn’t some all-or-nothing tug-of-war with winners and losers.

This is a world of communities with different infection levels, different cultures, different resources, and different individual needs.

Getting the balance right is hard.

It will take the best we can do. 22/22

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Sarah Rasmussen

Sarah Rasmussen Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @SarahDRasmussen

19 Oct
@apsmunro @interpolated I have no problem with the article itself. It’s with the summary written for it, which you amplified without explaining any corrective context, not even the fact that those positive results were from random sampling, whereas the ordinary assumption would be targeted testing.
@apsmunro @interpolated In the meantime, you cheer on 0-follower 21-tweet trolls who attack me when I try to have a nuanced discussion where I simply ask questions about the level of evidence we should demand before advocating for a certain policy—a question relevant to your own advocacy. Image
@apsmunro @interpolated But in case it’s more helpful if I explain what I mean when I speak of recent cherry picking of headlines, articles and/or evidence standards... 0/n
Read 21 tweets
9 Oct
Schools and personally-acceptable risk (THREAD)

This thread is an attempt to address questions certain UK parents and school staff have raised to me.

I’m not an epidemiologist, but as a mathematician I’m weighing in on certain general notions of probability and risk. 1/12
No one knows how bad this 2nd wave will get. It depends on what hard and soft measures are implemented and when, and how they are supported.

But I think it is ethically and scientifically unjustified to trivialise the concerns of parents and school staff about school risk. 2/12
Yes, there’s now good evidence that the covid mortality rate for healthy under-19-year-olds is likely no worse than flu *for*that*demographic.*

But that is only one type of risk. 3/12
Read 13 tweets
3 Oct
@SmutClyde @michaelroston @ThePlanetaryGuy Unfortunately, neither my World Scientific institutional access through U Cambridge nor that through IAS Princeton includes IJGMMP—I guess limited demand.

But there’s a retracted Mac J Med Sci pub by the same authors (et al) w/ “topoisomerase-like waves.”
researchgate.net/profile/Uwe_Wo…
@SmutClyde @michaelroston @ThePlanetaryGuy The retracted article’s argument seems to go:

1) topoisomerase unwinds DNA,
2) um, waves can be kind of wound up looking (?),
3) ergo, waves could unwind DNA like topoisomerase.

Thing is, that doesn’t make sense topologically.
(And I’m a topologist for my day job.)
@SmutClyde @michaelroston @ThePlanetaryGuy Topoisomerase doesn’t unwind DNA like a ball of yarn; it untangles by *crossing*changes*—temporarily snipping DNA for it to pass through itself, thereby changing the embedded topology of the DNA as a tangle/knot.

Simply “pushing DNA around” with a wave would NOT change topology.
Read 9 tweets
27 Sep
@ingridjohanna66 @threadreaderapp Thanks!

Initially stumbled on all this by accident.

I’m new to Twitter. Have mostly tried the academic route on this. The letter of corr + systematic review I sent to LC&AH on this were rejected, and now my univ’s Research Gov Office is working with UKRIO to organise an audit.
@ingridjohanna66 @threadreaderapp I originally worked alone on this, since didn’t want to disrupt med researchers at a time like this.

I know journals are doing the best they can with an avalanche of submitted articles that could influence policy that saves/jeopardises lives.

Difficult to know how hard to push.
@ingridjohanna66 @threadreaderapp (To clarify, what I sent was rejected by the LC&AH editor without ever being sent to peer review.)
Read 4 tweets
25 Sep
School closures + bad science (THREAD)

Remember that 6 Apr Lancet C&AH systematic review on school closures--with that media-amplified "2-4%" statistic--by a UCL team led by RCPCH president + SAGE member Russell Viner?

It has some serious problems. 1/
thelancet.com/journals/lanch…
Why does this still matter?

1. Viner's Review continues to be cited. A lot.

2. School closure was a first-aid response. Transitioning to long-term solutions calls for reexamining the science.

3. Serious enough cases of bad science raise concerns about the source. 2/
My first alarm bell?

The Review Summary's claim that "school closures alone would prevent only 2-4% of deaths" is a badly mis-contextualised statistic from

--wait for it--

the very Imperial College study [31] that prompted UK govt to close schools. 3/
imperial.ac.uk/media/imperial…
Read 23 tweets
27 Aug
THREAD. 1/
Pure mathematician here. Great questions.

It's literally my job description to create mathematics that has no known real-world use.

It's true that algebra had applications even millennia ago. But that is *not* what motivated Pythagoras.
2/ Pure mathematicians develop math according to what’s beautiful or surprising, or connective between diff areas of math.

It's partly done as an act of human achievement and creation, and partly done knowing that real-world uses might be found yrs, decades, or centuries later.
3/ Classical math education was less about learning rote skills and more about learning to think creatively, logically, and critically.

For example with Euclid's geometry, "Sure these lines look parallel, but what assumptions are we making here? How do we know for sure?"
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!