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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
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1 Nov, 4 tweets, 2 min read
Israel begins gradual easing of lockdown measures as Covid-19 cases decline
-from18OCT2020
f24.my/6zCZ.T via @FRANCE24
Other reading on Israel's lockdowns...
theguardian.com/world/2020/sep…
theguardian.com/world/2020/oct…
wsj.com/articles/israe…
"“I never thought a lockdown was a healthy solution. But we reached a level of morbidity in which we had no choice,”"
theguardian.com/world/2020/oct…
"“It’s like trying to stop a huge truck from sliding downhill. We have to see how fast it is going and also its size. It’s easier to stop a small truck than a big truck,”"

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More from @MackayIM

ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
2 Nov
If there's a link provided, it points to an Emergency Use Only instruction document for the CDC's SARS-CoV-2 PCR (July here, may be other versions) in which there's a comment: testing had to use a viral sequence made in the lab because didn't have *quantified* virus isolates Image
This whole misunderstanding (I'm being generous) hinges on the word "quantified". CDC researchers *had* cultured virus (see 👇) in January & March, but they didn't have a preparation of virus in which they knew number of infectious particles present. That's the quantified bit.
When you know how many infectious particles present, you can determine the limit of the sensitivity of the RT-PCR, in those same terms. Which is nice but not essential.
You can also do this using the same viral sequence target, prepared & quantified in the lab as RNA. They did 👇 ImageImage
Read 19 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
29 Oct
1580-1350 BC
An Egyptian stele portrays a priest with a withered leg, suggesting highly infectious polio has existed for thousands of years.
1916 AD
A polio epidemic on New York, USA.
The 1900s saw epidemics of polio worldwide
2020
After extensive global vaccination programs, only a handful of wild cases can be found. Africa is declared free of wild poliovirus transmission.
Regions that include 90% of the world's population are now free of wild polio.
Read 6 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
25 Oct
Victoria records a zero case day!!
This is after reporting a 725 case day in the peak of Wave 2, ~80 days ago.
#donutday
It can be done.
Who else has brought so many community #COVID19 cases to zero?
❓Taiwan? Never got that high
❓Vietnam? As above👆
❓New Zealand? 👆
❓Thailand? 👆
❓Singapore (almost-9 its minimum so far)
❓Switzerland (almost)
❓Israel (almost)
❓China✔
This isn't the end of Victoria's story - of course.
Vigilance will need to remain as restrictions loosen further, but this *can* be done even in an urban setting, if there is willingness to go for it - from both leadership and community.
Read 4 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
24 Oct
A new version with colour & division inspiration from @UQ_News and strict mouse design oversight by @kat_arden (ver3.0).
It reorganises slices into personal & shared responsibilities (think of this in terms of all the slices rather than any single layer being most important) Image
This adds stay home if sick, cough etiquette and air filtration and limit time spent in crowds (thx @cwjohannsen )
Also adds the misinformation mouse (thx to @DamianTheAussie
& @jurreysi), which may become a rat in future versions
Constructive feedback welcome.
Previous thread and more recent prior versions
Read 4 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
18 Oct
To make it clear - @tibmolbiol, the company, did not "heavily cooperate" with me to write a 2002 review of real-time PCR. Katherine Arden and Andreas Nitsche leveraged their skillsets to create that lit review with me. Dr Nitsche was & is a scientist in his own right.
You can see some of Dr Nitsche's impressive research output here
pubmed.ncbi.nlm.nih.gov/?term=andreas+…
The question of whether Dr Nitsche is still affiliated with TiB is strange but it's not one I can answer. I see nothing nefarious with him being, or not being, affiliated. TiB is a huge provider of fee-for-service oligos * kits around the world
Read 7 tweets
ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 Profile picture
18 Oct
-sigh. Sometimes only part of what you say, and the intent of your convo with a journalist, comes through. This was that.

"‘Could be 10 cases, could be 100’: Alarming sign virus still in Qld
One of the state’s top virologists has warned Queenslanders"

...in a local paper.
I'm disappointed the worst scenario came out here instead of the other aspects - notably the uncertainty attached to sewage testing results - which we'd discussed. I got the impression this would not be an alarmist piece. My gut feeling was wrong.
So Queeanalders, to set the record straight, I also said that wastewater positive results could be from a boat, that it's publicly unclear how long sewage sits at a station before being treated. Also,
Read 6 tweets

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