Accelerated Evolution of SARS-CoV-2 in an Immunocompromised Host - reading for tomorrow nejm.org/doi/full/10.10…
Being a nerd, the first thing I did was to check if all of the spike mutations in the covid patient with "accelerated evolution" have been detected before in the 200K+ SARS-CoV-2 genomes on @GISAID using the @CovidCg browser covidcg.org
nejm.org/doi/full/10.10…
nejm.org/doi/full/10.10…
The answer is yes, all of the spike mutations shown in their figure except for N440D have been seen before, albeit there are other mutations at N440 (Y or K) that have been detected.
🤟@atchen_ for designing these SNVs to look like jellybeans @CovidCg covidcg.org
🤟@atchen_ for designing these SNVs to look like jellybeans @CovidCg covidcg.org
I'd like to take this opportunity to🏔️🌊☀️re-thank @atchen_ & Kevin Altschuler who designed and developed the COVID-19 Coronavirus Genetics covidcg.org. Without you, this idea of a public resource to track SARS2 mutations by location+date wouldn't have manifested.
I know people don't want to believe this, but COVID will be with us for the next 1-3 years. I've heard an expert predict that 2024 is when we go back to normal.
Until then we have to keep tracking SARS2 and how it evolves in response to patient immunity, vaccines & therapeutics.
Until then we have to keep tracking SARS2 and how it evolves in response to patient immunity, vaccines & therapeutics.
If your friendly neighborhood scientist was like me in June, bemoaning how they can't track emerging SARS2 mutations in real time, by country & date, please share @CovidCg covidcg.org with them.
You can analyze all 172.5K high quality SARS2 genomes from @GISAID
You can analyze all 172.5K high quality SARS2 genomes from @GISAID
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