Welcome to this #IEPA12 keynote talk by Ricardo Araya @ArayaBaltra_R from @GMentalHealth who promises to tell us all about preventing emotional disorders from a global perspective
Araya starts by talking about the different types of prevention:
-primary prevention (most important) aims to prevent disease before it occurs
-secondary prevention aims to reduce impact of disease that’s already occurred
-tertiary prevention (not covered in this talk)
#IEPA12
What causes depression? Are these causes modifiable? (risk factors)
When do we need to remove or counteract risk factors? (when known)
#IEPA12
We know very little about risk factors for emotional disorders, says Araya

Modifiable risk factors are most interesting (adverse circumstances & traumatic life events, psychological mechanisms)

Unmodifiable risk factors (gender, genetics)

#IEPA12
Even if we know risk factors that can be modified, it’s still difficult to know at what point during life cycles we intervene, e.g. during the first 1,000 days of life
#IEPA12
Different types of preventative interventions
-universal intervention (for the whole population, e.g. in schools)
-selective and indicative (targeted) interventions for high risk groups or those with subclinical symptoms
#IEPA12
Araya developed a school intervention for 14-15 y/o children to improve mental health on low income in Chile. Schools didn’t want a targeted intervention that singled-out specific kids, so a universal intervention was developed. It didn’t work. #IEPA12
doi.org/10.1001/jamape…
So they tried an indicated intervention instead for kids with high depressive symptoms, but again this did not work (Gaete BMC Psychiatry 2017) #IEPA12
Heckman (early investment work) inspired Araya and his team to focus on younger children in their trials #IEPA12
Early life and development of executive function #IEPA12

We need to intervene early if we are going to really help young people at risk of mental illness, says Araya
Smithers 2018 Nature Human Behaviour review on early cognitive skills gave hope that there is some evidence that non-cognitive skills might be associated with improved outcomes (but research is very poor quality) #IEPA12
nature.com/articles/s4156…
This inspired Araya to develop a digital game for pre-school children (JAPI) - a new tool to stimulate cognitive (working memory and control inhibition) and non-cognitive (emotional recognition and social problem solving) skills #IEPA12
Araya's team piloted the JAPI app across 10 sessions, each 20-mins long that took place in the classroom #IEPA12
At 14 y/o kids may already have a high load of emotional symptoms that mean it's too late for prevention, says Araya
-We must develop tools to counteract potential risk factors before symptoms ensue
-Digital tech may be a good solution
#IEPA12
You tweeps might like to hear from Ricardo Araya @ArayaBaltra_R himself, so here he is speaking to me at the #MHNR2019 conference last year.

He talks about depression and global mental health in this short interview soundcloud.com/national-elf-s… #IEPA12

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More from @Mental_Elf

17 Nov
And now it’s time for our final #IEPA12 keynote from Rodrigo A Bressan @RodrigoAffonse1 who is going to talk about Widening the clinical and geographical frontiers of neurodevelopmental studies - the Brazilian High Risk Cohort Study Image
We’ve heard this statistic a few times during #IEPA12
75% of mental disorders start before age 18. Bressan adds that 50% of mental disorders start before age 14.
So “we need to understand the biology very early on, not after onset”. ImageImage
When we start identifying people with symptoms we don’t have good predictors of trajectories, says Bressan
#IEPA12
Read 29 tweets
17 Nov
Our next speaker is Louise Arseneault @L_Arseneault from King’s College London who will be talking about Early intervention for developing positive social relationships: can we prevent bullying victimization and loneliness? #IEPA12 Image
The absence of social relationships, or problematic ones may lead to mental health problems, says Arseneault. At the same time, positive social relationships can protect our health and wellbeing. They are important malleable factors that can be target by interventions. #IEPA12
Transition periods in the human life course (starting school, relationships, jobs and retirement) are potentially tricky times, says Arseneault #IEPA12 Image
Read 35 tweets
17 Nov
Our next #IEPA12 plenary talk comes from Juliana Onwumere @Families_MH from King’s College London who will be sharing some “Tales from the frontline: Understanding the impact of psychosis on families” Image
Onwumere begins by talking about the cognitive model of caregiving in psychosis, which she published with Elizabeth Kuipers and Paul Bebbington in @TheBJPsych back in 2010 doi.org/10.1192/bjp.bp… #IEPA12
We know that people with lived experience of psychosis can have significantly reduced social networks and informal carers can play an important role in these networks #IEPA12
Read 37 tweets
17 Nov
Our first speaker in this #IEPA12 session is Cristiane Duarte (not on Twitter) from @CU_ChildPsych @ColumbiaPsych who will be talking to us about: Intergenerational Psychiatry: A New Look at a Powerful Perspective #IEPA12 Image
Cristiane Duarte is an expert in the development of mental disorders in children, adolescents and young adults #IEPA12
Intergenerational Psychiatry
Duarte is going to talk about:
-definition, animal & human evidence
-role of adversities & perinatal period
-expanding our hypotheses (e.g. mechanisms of transmission)
-the Center for Intergenerational Psychiatry
#IEPA12
Read 27 tweets
17 Nov
Our final speaker in this #IEPA12 session of talk is Eric Chen (not on Twitter) from the University of Hong Kong who will be speaking to us about “Youth mental health in troubled times” Image
Eric Chen has been leading one of the first early psychosis intervention programmes in Asia: the EASY programme (Early Assessment Service for Young People with Early Psychosis) #IEPA12 www3.ha.org.hk/easy/eng/servi…
Most mental health conditions (75%) start before the age of 25, says Chen #IEPA12 Image
Read 20 tweets
17 Nov
Our next talk at #IEPA12 is by @pimcuijpers from @VUamsterdam who will be focussing on preventing the onset of depressive disorders: the opportunities and challenges pimcuijpers.com/blog/
“I’m always happy to talk about research on preventing the onset of depression", as there are lots of opportunities for helping people, says Cuijpers #IEPA12
Preventing depression: a global priority

This 2012 viewpoint by Cuijpers in @JAMA made the case for depression prevention and highlighted that the global biomedical community were ready for this idea (preventing depression) #IEPA12

doi.org/10.1001/jama.2…
Read 13 tweets

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