Thread by @AnilvanderZee

@mellojonny @DianeOLeary @rmm_0811 @eleanormorgan @ObsMagazine 1) Thank you for sharing. Great perspective from a GP. Really caring is of the utmost importance, but as I explained in my blog. If clinicians lack basic knowledge miscommunication & therefore possible iatrogenic harm might still be just around the corner.

I think that's also

@mellojonny @DianeOLeary @rmm_0811 @eleanormorgan @ObsMagazine 2) why the #ACE subject exploded. Previous studies (Heim et al., 2009) indeed showed a "well established link" between ACE & ME. However just like with the CBT/GET, it was based on broad empirical definition of ME or rather CFS.

The IOM report 2015 and Clark et al., 2007

@mellojonny @DianeOLeary @rmm_0811 @eleanormorgan @ObsMagazine 3) disagree with Heim et al.. Once controlled for these factors Clark et al. found rates from 61% to only 17%. I personally don't think this correlation will be any different with #LongCovid. Therefore the link is indeed old but also imo debunked news.

tandfonline.com/doi/full/10.10…

@mellojonny @DianeOLeary @rmm_0811 @eleanormorgan @ObsMagazine 4) I don't think anyone tries to devalidate the experience of the patient on purpose but because of that lack of knowledge it happens rather often. I'm however really pleased that you are so willing to have an open discussion although you had quite a bit of pushback! That is

@mellojonny @DianeOLeary @rmm_0811 @eleanormorgan @ObsMagazine 5) That's fantastic! Thank you!

I haven't read this preprint but it might be of interest to you!

https://twitter.com/AnilvanderZee/status/1333540904544694277?s=19

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