UPDATE: I've been digging through Pfizer's vaccine data. It's incredibly encouraging and frankly, I'm stunned that this was all done in one year.
The FDA's advisory panel will review this data publicly on Thursday. You can check it out here: 1/
fda.gov/media/144245/d…
The FDA's advisory panel will review this data publicly on Thursday. You can check it out here: 1/
fda.gov/media/144245/d…
mRNA vaccines are described as new (there aren't any on the market) but they've been studied for decades. Pfizer has overcome the challenges limiting their use, including: 1) instability of free RNA in the body, 2) unintended inflammatory outcomes, & 3) mild immune responses. 2/
It's also reassuring that Moderna had such similar topline results using the same mRNA platform. This doesn't appear to be an aberrant outcome.
If there's one thing I'd like to know more about from Pfizer's data, it's at the bottom of page 43: 3/
If there's one thing I'd like to know more about from Pfizer's data, it's at the bottom of page 43: 3/
"In the vaccine group, one participant with baseline obesity and pre-existing atherosclerosis died 3 days after Dose 1..."
Statistically, we know bad things will happen to people whether they receive a vaccine or not. But it's not hard to imagine how some might interpret this. 4/
Statistically, we know bad things will happen to people whether they receive a vaccine or not. But it's not hard to imagine how some might interpret this. 4/
It will be important to achieve clarity on this, and to address a handful of cases of appendicitis in the vaccine group, to strengthen public messaging. Overall, great results!
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