Here's the brand new FDA analysis of Moderna's vaccine prepared for Thursday's meeting:
fda.gov/media/144434/d…
fda.gov/media/144434/d…
Moderna doesn't report quite so high Vaccine Efficacy for over 65s: 86.4%.
"The VE in this analysis when stratified by age
group was 95.6% (95% CI: 90.6%, 97.9%) for participants 18 to <65 years of age and 86.4%
(95% CI: 61.4%, 95.5%) for participants ≥65 years of age."
"The VE in this analysis when stratified by age
group was 95.6% (95% CI: 90.6%, 97.9%) for participants 18 to <65 years of age and 86.4%
(95% CI: 61.4%, 95.5%) for participants ≥65 years of age."
"Throughout the safety follow-up period to date, there
were three reports of facial paralysis (Bell’s palsy) in the vaccine group and one in the placebo
group"
I think Pfizer had 4 Bell's Palsy in vaccine and 0 in placebo, so that's 7 cases for 35k inoculated with either.
were three reports of facial paralysis (Bell’s palsy) in the vaccine group and one in the placebo
group"
I think Pfizer had 4 Bell's Palsy in vaccine and 0 in placebo, so that's 7 cases for 35k inoculated with either.
If I'm doing the math right, there was 1 case of Bell's palsy for every 5,000 vaccinated across both Pfizer and Moderna mRNA trials, vs. 1 out of 35k in placebo arms. Could be something or could be a fluke.
But don't take my word for it.
But don't take my word for it.
From the FDA's analysis of Moderna's vaccine:
"The frequency of serious adverse events was low (1.0% in the mRNA-1273 arm and 1.0% in the placebo arm), without meaningful imbalances between study arms."
That sounds good.
"The frequency of serious adverse events was low (1.0% in the mRNA-1273 arm and 1.0% in the placebo arm), without meaningful imbalances between study arms."
That sounds good.
Moderna's final analysis of Vaccine Efficacy:
11 Covid cases in Vaccine Arm
185 cases in Placebo Arm
94.1% Efficacy
Only 86.4% in 65+: 4 cases vs. 29 cases.
If you lump Moderna results with Pfizer (both are mRNA), you get about 90% VE in elders.
fda.gov/media/144434/d…
11 Covid cases in Vaccine Arm
185 cases in Placebo Arm
94.1% Efficacy
Only 86.4% in 65+: 4 cases vs. 29 cases.
If you lump Moderna results with Pfizer (both are mRNA), you get about 90% VE in elders.
fda.gov/media/144434/d…
In Moderna vaccine trial, 30 severe cases of covid (9 hospitalized, 1 died) were seen.
All 30 severe cases were in the Placebo group. Zero in Vaccine group.
Sounds good.
fda.gov/media/144434/d…
All 30 severe cases were in the Placebo group. Zero in Vaccine group.
Sounds good.
fda.gov/media/144434/d…
The Moderna vaccine starts to work about 14 days after the first dose:
Pfizer vaccine:
8 cases in vaccine group, 162 cases in placebo group
Moderna vaccine:
11 cases in vaccine group, 185 in placebo group
Total:
19 cases in vaccine group, 347 in placebo group
This stuff works.
8 cases in vaccine group, 162 cases in placebo group
Moderna vaccine:
11 cases in vaccine group, 185 in placebo group
Total:
19 cases in vaccine group, 347 in placebo group
This stuff works.
Somebody should go through the Moderna
fda.gov/media/144434/d…
and Pfizer vaccine FDA analyses
fda.gov/media/144245/d…
and add together the results to double the sample sizes, such as for adverse events.
Also, where do the two mRNA vaccines differ much?
fda.gov/media/144434/d…
and Pfizer vaccine FDA analyses
fda.gov/media/144245/d…
and add together the results to double the sample sizes, such as for adverse events.
Also, where do the two mRNA vaccines differ much?
The Moderna vaccine trial was was held up for a month due to the Warp Speed requirement they recruit more nonwhite volunteers. (Whites volunteer faster on average). This kept them from announcing success before the election.
Now it turns out vaccine works the same for all races
Now it turns out vaccine works the same for all races
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