Gentle note to writers: opioid use *constricts* the pupil. Withdrawal causes dilation.
If you are a writer and want a nice layperson introduction to effects of opioid intoxication and withdrawal, trainspotting does a great job.
This is a very nitpicky point but “opiates” cover opioids derived from the poppy plant whereas opioids covers all of them including the man-made ones like methadone.
I think opiates is a nicer, more elegant word so for fiction writing I might use it anyway and before 1943 there were only opiates anyway. (I think...vague recollection Germany developed methadone when they lost access to opium poppy supplies in WWII but could be wrong)
There’s sort of a romance of opioid use in literature and film, especially historical...pretty people lazing around smoking pipes or ladies and their laudanum...the blown pupil fits that better than the constricted one which is why it’s *always* wrong I think.
If your opioid-addicted person has a blown pupil he is not a happy camper *at all* and will also be restless, sweaty, nose running, GI issues, pain, and muscle cramps so I always find the blown pupil drugged up character jarring.
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...honestly I would discount any patients super sick in the hospital reports as “new onset psychosis” it’s probably delirium. But the outpatient cases sound like delusional disorders. Unlike schizophrenia which tends to hit late teens, 20s for men and 20s-30s for women...
...or there’s a second peak for women at menopause, delusional disorder tends to strike middle age people. Not surprised there could be an infectious (inflammatory) precipitant.
Now that we have a few vaccines that seem to work do y’all want to hear my really grim theoretical predictions for the pandemic if the worst things happened?
I hadn’t widely shared them because they are awfully negative. Fortunately I think we will most likely be spared at this point. But their possibility made the #flubro crowd especially irritating to me.
we know sars-cov-2 infects many other species (rodents, cats, dogs), though not necessarily to them and back to humans. However they definitely go to minks and back to humans. This means it’s really really tough to get rid of completely. Also more opportunity for mutation.
Trying to imagine the pandemic course if we had a competent federal government. That 6 week testing delay cost us a lot of lives. Earlier surveillance and testing would have meant spring lockdowns started a bit earlier, eliminating the northeast huge peak in April.
Nothing would have prevented the southern states from opening up without care => the summer peak, but lower levels of virus in the country from the spring might have mitigated it a little.
By September a government that had it together probably could have blanketed the country with rapid tests. Frequent testing + social distancing measures mitigated and prevented outbreaks in colleges in Massachusetts and the NBA and entertainment and news industries.
Y’all there is one Malaysian factory that produces most of the world’s medical grade nitrile gloves and they had >20k workers sick with COVID and several large medical centers are going to run out of gloves by the weekend.
The US reserve stockpile of nitrile gloves is almost extinguished.
Restaurant grade could be a substitute for many indications but the raw materials are the same and the backlog is extensive.
There was a fair case for considering the #flubro argument at the beginning. But with the example of Sweden and with large scale vaccination of the front lines and vulnerable mere months away, all #flubroism is exposed for eugenics. May your foul philosophies be shunned.